This selection of articles from the Encyclopedia of the Eye is the first single-volume overview presenting articles on the function, biology, physiology, and pathology of the structures of the ocular periphery, as well as the related disorders and their treatment. The peripheral structures are implicated in a number of important diseases, including optic neuritis, thyroid eye disease, and strabismus. The volume offers a basic science background of these topics rather than a strictly clinical focus. - The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of the ocular periphery - Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers - The best researchers in the field provide their conclusions in the context of the latest experimental results

A comprehensive understanding of diseases of the peripheral retina is essential to the general ophthalmologist as well as to the vitreoretinal surgeon. Expertise in in direct ophthalmoscopy, scleral depression, and contact lens biomicroscopy serves as a basis for observing the peripheral retina. These observations are then re corded on fundus drawing paper and the Tolentino vitreo-retinal chart. This or derly sequence of skills allows the ophthalmic surgeon to objectively diagnose and evaluate specific peripheral retinal disorders and plan for their therapeutic management. The Clinical Atlas of Peripheral Retinal Disorders is a compilation of fundus paint ings by David A. Tilden based on our observations of a large number of patients over the past 15 years. The atlas is organized along functional and anatomical lines. After a brief introduction to the clinical anatomy of the peripheral retina, the appearance of the fundus as a function of skin color and aging is presented. Many of the diseases of the peripheral retina can be divided into trophic (nutritional), tractional, and a combination of trophic plus tractional etiologies. This classifica tion system, although somewhat simplistic, appears adequate for our present level of understanding of the pathogenetic mechanisms of these disorders. Un doubtedly, once the molecular biology of these conditions is elucidated through future research, the classification will be revised. In addition, there are other con ditions that affect the peripheral retina that do not fit the proposed classification system and are covered under separate headings, i. e.

Dominant exudative vitreoretinopathy (DEVR) is an eye disease which has only recently received wider attention. In 1969 Criswick and Schepens used the designation "familial exudative vitreoretinopathy" to describe a syndrome they observed in six patients belonging to two families. The condition was characterized by several symptoms involving the vitreous and retina, e. g. "posterior vitreous detachment, organized vitreous membranes, heterotopia of the macula, retinal neovascularizations, subretinal and intraretinal exudates, and localized retinal detachment". The clinical features impressed the authors as strongly reminiscent of retrolental fibroplasia, but none of the patients had a record of premature birth or postnatal oxygen administration. In 1971 Cow and Oliver described the same syndrome in several members of one family. They considered their findings to be compatible with auto somal dominant transmission. Canny and Oliver (I976) were the first to de monstrate the fluorescein-angiographic changes of DEVR in four members of the abovementioned family. The most striking finding was "abrupt cessation of the capillary network in a scaloped edge near the equator". Fluorescein was seen to leak from the retinal vessels localized in this marginal zone, and in some eyes from massive fibrovascular lesions as well. Similar fluorescein angiographic changes have been described in recent years in other reports on families with DEVR (Nijhuis et aI., 1979; Slusher and Hutton, 1979; Dudgeon, 1979; Ober et a1., 1980; Laqua, 1980). In 1979 I commenced a clinical study of this still little-known condition at the Nijmegen University Institute of Ophthalmology (The Netherlands)

Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities. - Covers both hereditary and cryptogenic neurologic disorders - Includes advances in the basic science of PNS from molecular genetics, biochemistry, immunology, morphology and physiology - Detailed coverage of neuropathy in connective tissue disorders, infectious disorders, metabolic disorders and malignancy

Peripheral neuropathies represent a challenging subject for most physicians. This is an up-to-date, comprehensive, and readable book on peripheral neuropathies that includes concise information on the clinical, electrophysiological, pathological, pathogenic, and treatment aspects of the most important disorders. New molecular and serologic diagnostic tests are discussed. Sections are devoted to nerve and skin biopsy techniques and findings, quantitative sensory and autonomic reflex tests. Case examples are used liberally throughout the text. The editors: Mendell, Kissel, and Cornblath are experienced clinicians that bring complementary knowledge to each of the subjects. Additional authors have been handpicked for specific topics which add to the value of the edition.

Peripheral Nervous System Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Peripheral Nervous System Diseases in a concise format. The editors have built Peripheral Nervous System Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Peripheral Nervous System Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Peripheral Nervous System Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Cardiologists today must have adequate basic training in vascular medicine in order to care for patients with peripheral vascular diseases. However, the topic of peripheral vascular disease has been inadequately addressed in most training programs, and particularly in the literature directed toward cardiologists. This text, the first of its kind, is intended to broaden their knowledge base and clinical skills in the recognition and management of the common peripheral vascular disorders occuring in cardiovascular practice. Peripheral Vascular Disease for Cardiologists will provide a practical, clinical framework rather than using the usual textbook format, hence fitting effectively within training programs in cardiology and internal medicine.