A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.

The field of rheumatology has undergone numerous exciting advances in recent years, especially the development of biological drugs with novel targets, made possible by rapid advances in the basic science of musculoskeletal diseases together with improved imaging techniques. This thoroughly revised fourth edition of the Oxford Textbook of Rheumatology reflects the changing face of the specialty and the many recent advances in the science, treatment, and understanding of rheumatic diseases. The focus of this comprehensive reference work is the presentation and management of rheumatic conditions at all ages. Where relevant, treatment approaches are evidence-based and cross-referenced to national and international guidelines. Each clinical chapter provides up-to-date treatment advice illustrated with clinical vignettes as appropriate, and the authors consistently emphasize the overlap of rheumatology with other disciplines. With full colour illustrations throughout and a complementary online version, the Oxford Textbook of Rheumatology, Fourth Edition is an essential reference for all trainees and specialists in the field.

This brand new textbook of rheumatoid arthritis (RA) is an important addition to the Oxford Textbooks in Rheumatology series, and provides a comprehensive overview of both the scientific and clinical aspects of the disease. Divided into eight sections - from the history, diagnosis, and epidemiology of the disease, through the pathogenesis, clinical presentation, and assessment to treatments and management strategies, both drug- and non-drug based - each chapter is written by leading clinicians and scientists in the field to deliver a contemporary view of RA. During the past two decades there have been revolutionary changes in the understanding and management of rheumatoid arthritis, in particular the development of biological treatments. This has had wide-ranging effects on almost all aspects of treatment, from effectiveness and intensity to the nature and the cost. Providing a comprehensive account of the modern ideas about the disease, the Oxford Textbook of Rheumatoid Arthritis is a key new addition to the literature, with each chapter providing a detailed background, key recent advances, and areas of doubt and future developments. Featuring over 170 photographs, radiological images, and clinical charts to aid both diagnosis and illustrate the rationale behind key scientific studies, this new title will prove an indispensable resource for specialist rheumatologists, trainees in rheumatology, and other members of the multi-disciplinary team.

Extensively revised and fully updated, this new edition of the Oxford Handbook of Rheumatology provides everything you need to understand the wide range of rheumatic conditions. Including the latest guidelines and the most up-to-date information, this is the indispensible guide for students, trainees, consultant rheumatologists, and everyone dealing with patients with musculoskeletal disease. Rheumatic conditions are common in both general and hospital practice; a primary feature of many multi-system illnesses, and in the context of injury, age-related change, and psychological distress. This handbook provides practical advice, guidance, and key clinical facts to help you provide the best care for your patients. Practically structured, the handbook focuses first on presenting symptoms, and then considers key diseases, emergencies, and rare diseases in more detail, finishing with a comprehensive account of assessment, guidelines, and treatment options including the latest advances in biological therapy. It provides practical guidelines on the management and diagnosis of patients with acute and chronic musculoskeletal disease. Colour plates and line drawings are present throughout along with tables of key information. Taking a clinical, evidence-based approach, written by experts, and presented in a clear, practical, bullet-point style for rapid reference, this handbook will be your constant companion and a joy to use.

The Oxford Textbook of Medicine provides all that any doctor needs to know to practice top-level internal medicine. It gives compreensive coverage of the epidemiology, aetiology, and mechanism of disease, as well as clear, unambiguous coverage of the diagnosis, practical management and prevention of the entire spectrum of medical disorders. There are major introductory sections on the scientific basis of disease; and in the system-based clinical sections genetic predisposition, pathophysiology, pathogenesis, molecular mechanisms, and cell biology are covered in depth for all significant medical syndromes. Clinical descriptions of diseases are clearly and memorably written, based on the experience and insight of the authors--many of whom are among the world's most distinguished medical scientists. Chapters are not only "evidence based" but also on clinical experience and a thorough survey of all the relevant literature. Throughout, the approach of OTM is humane and ethical and, at the same time, factual, reliable, honest(especially where knowledge is limited) and rigorously scientific. This is not just a textbook of "First World" medicine. It provides practical guidance for doctors working in a variety of medical setting the value of a logical clinical approach rather than immediate resort to expensive imaging and laboratory tests. Moore of the contributing authors than ever before are from outside Europe, including strong representation of North American medicine. The new editorial team has ensured that the OTM continues to reflect rapid changes in medical practice: there are new sections on intensive care, alcohol and drug abuse, clinical pharmacology and therapeutics, world health, clinical trials and evidence-based medicine, adolescent medicine, sports medicine, and emergency medicine; more than half the contributors are new for this edition; and most of the text has been heavily revised. The striking new page and cover design reflect the significant changes made in this new edition. The Textbook is illustrated by over 2000 two-color diagrams and many color Plates. The index is the most detailed and user-friendly of any major medical textbook: in an emergency, the reader can access information quickly- whether on the ward, in office or at home. Like its predecessors, OTM4 will be the trusted and ultimate reference in libraries, hospitals, doctors' consulting rooms, solicitors' offices, press offices, and primary care practices worldwide.

The Oxford Textbook of Paediatric Pain brings together clinicians, educators, trainees and researchers to provide an authoritative resource on all aspects of pain in infants, children and youth.

Axial Spondyloarthritis is a timely addition to the Oxford Textbooks in Rheumatology series, providing a comprehensive reference to this rapidly evolving field. The conceptual framework of the disease has now evolved beyond ankylosing spondylitis to encompass a broader concept of axial inflammation. Earlier recognition has opened the door to earlier intervention, and the understanding of the biologic basis of axial SpA has seen significant advances in recent years. The first textbook to cover axial spondyloarthritis in this level of detail from a global perspective, this volume offers a practical and complete resource compiled by a multidisciplinary and multinational team of experts. Beginning with a historical perspective on the disease, the textbook provides a comprehensive background in the epidemiology, diagnosis, and classification of axial spondyloarthritis. Immune mechanisms and genetics are covered, along with imaging and a detailed section on the range of treatments options currently available. A section on extra-articular manifestations provides a comprehensive knowledge base for the clinician treating patients with spondyloarthritis, and chapters on the economics of the disease, physical functioning, and patient registries complete the broad coverage of the topic. Practical, easy to use, yet detailed with respect to pathophysiology, diagnostics, and management, this textbook provides a comprehensive reference for rheumatologists, general practitioners, internists, and paediatricians managing patients with axial spondyloarthritis.

The oxford textbook of paediatric pain brings together clinicians, educators, trainees and researchers to provide an authoritative resource on all aspects of pain in infants, children and youth.

This updated and revised textbook provides comprehensive coverage of common polygenic and rare monogenic disorders, emphasising advances in bone cell biology and human skeletal disease. Accessible and well-illustrated, this concise account of metabolic bone disease is designed for postgraduates and clinicians.

Filled with practical advice from experienced nurses and up-to-date clinical information, this new edition of the Oxford Handbook of Musculoskeletal Nursing is the invaluable guide for all nurses and allied health professionals working with patients who have rheumatological and musculoskeletal conditions. Written to ensure that a nurse in any care environment will have the core information they require at their fingertips, this Handbook is split into three sections: musculoskeletal conditions and their management; clinical issues; and nursing care issues including treatment, nursing management, and tools. Management approaches have been fully updated since the first edition, and the changing healthcare environment and available treatments have been considered, alongside the move towards patient self-management and self-care. This Handbook also addresses the increasing demand for guidance in relation to musculoskeletal conditions, as the growing elderly and chronic disease populations needs for healthcare continue. Featuring brand new chapters on the patient's perspective, nurse-led clinics, and public health awareness, the Oxford Handbook of Musculoskeletal Nursing second edition is a practical and comprehensive guide to help the reader reach the best possible results for their patients.