This book covers the huge advances made in clinical diagnosisenabling earlier detection, while addressing the recent progressmade in treatment of hepatocellular carcinoma (HCC) to enablesuccessful therapy. It draws on the expertise of an internationally recognizedauthor famed for his understanding, knowledge and efforts indefining terms and diagnosis in this area. The text reviews the full range of pathological information ofHCC based on the study of surgical cases and biopsy materials,along with images, to help compare findings that may be encounteredby pathologists. It also makes special reference to developments inearly stage HCC detection and premalignant lesions which canincrease effective treatment.

This atlas is designed to be a user-friendly bench-side reference for pathology trainees and general pathologists in handling and interpreting specimens of hepatocellular carcinoma. It provides over 550 high-quality gross and microscopic photos focusing on hepatocellular carcinoma and its mimickers, and demonstrating a full range of various histological variants of hepatocellular carcinoma. Introductory text in each chapter summarises salient clinical associations, pathological features, and molecular alterations of different variants of hepatocellular carcinoma. Differentiation between hepatocellular carcinoma and its mimickers is illustrated through various case studies. The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high./divThe authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high./divThe authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high./div

Pathology of Liver Diseases is a rapid reference consultation tool that uses both book and online material to present a whole range of liver disorders. The book emphasizes not only the pathology seen in biopsy and surgical material, but also the most pertinent clinical and laboratory findings including epidemiology, etiologic and pathophysiologic concepts, and the differential diagnoses. Key references appear at the end of each chapter. The book is also accompanied by a companion website: www.wiley.com/go/kanel/liverpathology It contains the following online material: A complete Reference List. A Library that contains over 860 images of the various liver diseases, which adds to over 540 images that are in the book itself Additional Tables that address in detail the grading and staging of various liver diseases such as viral hepatitis and fatty liver diseases. 140 Case Examples, which include over 420 images that demonstrate the various ways many of these disease entities clinically present. A PowerPoint presentation entitled "Liver Transplantation – Surgical Procedure", which includes photographs from the operating table of the step-by-step process in liver transplantation. Pathology of Liver Diseases provides gastroenterologists and pathologists with a multi-media, well-illustrated, and concise guide to the pathology and clinical diagnoses of liver disorders.

This book focuses on the pathological diagnosis of primary hepatic and bile duct tumors, and introduces the “Three Types and Six Sub-types” classification of hepatobiliary tumors. With more than 600 figures, including photographs and microscopy images, it highlights morphology, immunology and molecular pathology and their correlations with hepatic surgery and hepatic oncology. The book reviews the pathobiological characteristics of hepatic tumors and reveals the latest developments in this field. It is a valuable reference resource for hepatologists, pathologists and researchers.

Highly illustrated and conveniently templated for quick reference, Atlas of Liver Pathology, 4th Edition, is a useful Atlas and text for every practicing pathologist or trainee who assesses liver biopsy specimens. From cover to cover, it contains all the information needed to identify histologic features and correlate them with clinical findings, offering a clearer understanding of the clinical implications of the disease as it relates to treatment. More than 1,200 high-quality, full-color images and illustrations provide you with a complete visual guide to the vast majority of liver diseases and assist in the diagnoses of biopsy and resected liver specimens. - Provides clear, templated information for each disease: Major Morphologic Features; Special Stains; Differential Diagnoses; Clinical and Biologic Behavior; and Treatment and Prognosis. - Incorporates relevant data from ancillary techniques (immunohistochemistry, cytology, cytogenetics and molecular genetics), giving you the necessary tools required to master the latest breakthroughs in diagnostic technology. - Incorporates the latest diagnostic biomarkers and their utility in differential diagnoses, newly described variants, and new histologic entities. - Contains two new chapters on liver biopsy interpretation and autoimmune hepatitis. - Features concise, bulleted text and abundant tables that cover common as well as rare diseases, differential diagnoses, and more.

This text provides a practical guide for the diagnostic surgical pathologist in evaluating tumors involving the liver. It comprehensively covers the histological findings and key clinical and molecular correlates of liver tumors. The focus is on material that is most relevant to the actual practice of liver pathology including those aspects that are directly relevant to the diagnosis, subtyping and prognostication of hepatic adenomas specimens, including biopsy specimens and surgical resections. The book will teach pathologists how to avoid common diagnostic pitfalls. Each chapter uses or discusses the nomenclature and classification system of liver tumors as per the current WHO classification of liver tumors. Each chapter fully incorporates the most up to date diagnostic methodologies, including immunohistochemistry and molecular methods. Referencing is succinct and references were carefully chosen for their key role as the primary sources of information on a given disease. The text is richly illustrated with beautiful color images that highlight not just the “average” histological findings for a given entity, but also fully illustrate all of the key histological variability. Gross images are also included to highlight important diagnostic features. Tables are used judiciously to present summary information that allows a quick review on how similar entities compare and contrast. In addition, the clinical significance of various diseases will be discussed in a focused fashion that highlights how pathology information is being used to make key clinical management decisions. Each chapter is written by experts in hepatopathology, all from the Mayo Clinic Departments of Pathology. Surgical Pathology of Liver Tumors will be of great utility to surgical pathologists and surgical pathologists in training as well as clinicians involved in the care of patients with liver tumors, particularly hepatologists and oncologists.

This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC. Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.

A volume in the popular Pattern Recognition Series, Practical Hepatic Pathology: A Diagnostic Approach features completely updated and reorganized content, resulting in a truly practical guide to understanding liver pathology. Dr. Romil Saxena presents interpretation of liver biopsies according to a pattern-based approach that begins with recognition of the predominant histological pattern of injury, followed by identification of secondary features and appropriate work-up that lead you away from pitfalls to the best diagnosis. Unique "visual index" at the beginning of the book references the exact chapter and specific page needed for in-depth diagnostic guidance. Superb, high-quality, full-color images illustrate pathognomonic features and common variations. Features comprehensive information on major adult and childhood liver diseases, hepatic neoplasms and pre-neoplastic nodules, including clinical features, laboratory tests, imaging findings and differential diagnosis. Coverage of the clinical aspects of liver transplantation allows you to understand the pathology and practice of this procedure. Virtual Microscope provides your own personal set of over 300 liver slides accessible anywhere, any time on your favorite digital device. Navigate around and zoom in and out to savor these exceptionally high quality whole slide images covering everything from the normal liver to rare challenging cases. New section on Evolving Concepts keeps you abreast of new paradigms in liver diseases such as reversal of fibrosis, heterogeneity of cirrhosis, and biphenotypic primary liver cell carcinoma. Reorganized Table of Contents is even more intuitive.

Needle biopsy of the liver is now an accepted procedure in most large hospitals, and surgeons and laparoscopists are more likely to biopsy the liver under direct vision than in the past. Consequently, increasing demands are being made on pathologists for rapid diagnosis. This full colour atlas provides a practical guide to the histopathological diagnosis of liver disorders, with particular emphasis on clinicopathological correlation and the need for the pathologist to be in full possession of all the available clinical information. Although containing over 350 colour illustrations, the book is more than just an atlas and each section includes a brief description of the main clinical and pathological features of the subject under discussion. For this second edition, many chapters have been rewritten - e.g. on viral hepatitis - and many new illustrations added. The book is intended for the practising and trainee pathologist and the clinician who performs liver biopsies, but will also be of value to postgraduates, residents and students in other branches of medicine.

This unique book provides detailed insight into a wealth of expert experience in liver pathology, with an in-depth review of the expertÌs analysis and diagnostic process supported by high-quality color photomicrographs and discussion of the diagnostic principles involved in evaluating these lesions. The diagnostic problems and cases selected show the wide range of specimens seen in liver pathology and address the difficult issues in diagnosis encountered in these lesions. Chapters and cases are authored by many of the leading experts and educators in liver pathology today. Liver Pathology will be essential reading for every pathologist who evaluates liver pathology specimens. In addition it will be a valuable resource for pathology residents and fellows. All Consultant Pathology Titles Provide: Actual consultation cases and expert analysis Expert analysis provides a detailed discussion of the reasoning behind the diagnosis of each case Comprehensive coverage of challenging diagnoses The cases are richly illustrated with high-quality photomicrographs