The Guest Editors have compiled a comprehensive issue that includes both disorders of endocrinology as well as diabetes. Authors have addressed the following clinical topics: disorders of menstruation, thyroid function; gender dysphoria; hypoglycemia in the nondiabetic child; preventing DKA; short- and long-term outcomes in diabetes, and whole genome sequencing in endocrinology. These topics represent the current knowedge in the field, and pediatricians will have the most updated clinical information as they evaluate and treat children with diabetes or endocrinology disorders.

This issue of Endocrinology and Metabolism Clinics, edited by Dr. Robert Rapaport, is devoted to Pediatric Endocrinology. Articles in this issue include: Thyroid Cancer in Pediatrics; Gender and Sex Assignment; CAH Prenatal Diagnosis; Diabetes; Polycystic Ovarian Disease; Newborn Screening for X-linked ALD; Growth in Patients w/ Skeletal Dysplasia; Thyroid Imaging in Infants; Bariatric Surgery in Youth; Pituitary Imaging in Pediatrics; and Cardiac and Metabolic Features of GH Deficiency.

This issue of Endocrinology and Metabolism Clinics will cover Pediatric Endocrinology. Curated by Dr. Andrea Kelly, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Endocrine Sequelae in Childhood Cancer Survivors, Bone Health in Childhood Chronic Disease, Advances in Bone Health Assessment, Inhaled Glucocorticoids and Endocrine Outcomes, Atypical DM (mitochondrial, transplant, CFRD, monogenic), Pediatric Thyroid Cancer (outcomes, genetics, therapeutics), New Technologies in Type 1 diabetes (bionic pancreas, insulin, mobile health), Precocious and Delayed Puberty—Genetic Underpinnings and treatments (various GNRH formulations, implant), Pediatric Type 2 diabetes, Adolescent health outcomes in relation to phthalates.

In collaboration with Consulting Editor Dr. Bonita Stanton, the Guest Editors of this issue of Pediatric Clinics of North America have comprehensively review the current and future opportunities for implementing telehealth into pediatric practice. Expert authors have written review articles that provide information based on current knowledge of implementation of technologies but also ask questions about how to implement and what potential challenges there will be. Articles are specifically devoted to: Overview of Telehealth for Pediatricians; Role of Doctor—Patient Relationship in Telehealth; Design Purpose and Design Thinking for Telehealth; How to Implement Telehealth in Pediatrics; Issues Related to Adoption of Health Apps and Telemedicine Programs; Workforce Trends and Business Model for Telehealth; Moral, Political and Economic and Social Dilemmas of Telehealth; Automated Digital Health with Big Data, Predictive Analytics and AI; Tele-rounds and Cased-Based Training; Role of Text-messaging and Messaging apps in telehealth; High-Quality Telehealth Training Programs; Technical and Regulatory Issues of Telehealth Medicine; and Global Health Perspective on Telehealth. Pediatricians will come away with the information they need to employ telemedicine in their clinical practice

In this issue of Pediatric Clinics of North America, guest editors Drs. Gitanjali Srivastava and Eliana M. Perrin bring their considerable expertise to the topic of Obesity. Top experts discuss the latest research, early interventions, and treatments for obesity in pediatric patients, with the goal of helping clinicians intervene to prevent comorbidities, disease, and chronic health conditions into adulthood. Topics include bariatric surgery, pharmacotherapy, screening, and mental health and stigma, and more, providing state-of-the-art data and clinical information needed to improve outcomes in these patients. - Contains 15 relevant, practice-oriented topics including obesity as a health equity issue; the built environment in obesity; overview of pediatric obesity treatment and the new CPG guidelines; the toxic food environment and nutrition; the genetics of obesity; and more. - Provides in-depth clinical reviews on obesity, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Sethu K. Reddy, is devoted to Diabetes. Articles in this issue include: Approach to Multicultural Issues in Diabetes; Clinical Utility of Genetic Testing in T2DM; Utility of CGM - Type 1 and Type 2 Diabetes Mellitus; Islet Cell Transplantation; Use of Telemedicine; Nonalcoholic Steatohepatitis; Microbiome: Role in Type 1 and Type 2 Diabetes Mellitus; Population Management and Diabetes; Pre-diabetes; Metformin: What do we know?; Insulin: Making Sense of Current Options; Nutrition in Diabetes; Bariatric Surgery: Pathophysiology and Outcomes; Future Therapies in Diabetes; Lipodystrophic Syndromes; and In-patient Diabetes Management in the 21st Century.

In this issue of Endocrinology and Metabolism Clinics of North America, guest editor Dr. Osagie Ebekozien brings his considerable expertise to the topic of Type 1 Diabetes. Top experts in the field provide a timely update on type 1 diabetes care in children and adults, and provide recommendations for treatment and improving access to care. Contains 14 relevant, practice-oriented topics including type 1 diabetes population health improvement; access to care for type 1 diabetes; emerging technologies and therapeutics; social determinants of health (SDOH) in type 1 diabetes; COVID-19 and type 1 diabetes; and more. Provides in-depth clinical reviews on type 1 diabetes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Pediatric Clinics of North America, guest editors Drs. Roger W. Apple and Ethel G. Clemente bring their considerable expertise to the topic of Role of Psychologists in Pediatric Subspecialties. Top experts in the field highlight the interdisciplinary nature of primary care of children where psychology is a factor, placing emphasis the clinical topics, disease states, or medical specialties where mental health has a significant impact on the outcome and successful treatment of clinical issues in children. This issue offers a unique focus on collaboration between the psychologist and pediatrician to optimize outcomes. - Contains 16 practice-oriented topics including helping physicians collaborate with psychologists; psychologists' experiences in pediatric hematology-oncology; the role of psychologists in child abuse pediatrics; the critical role of psychologists in pediatric gastroenterology; the role of psychologists in pediatric sports medicine practice; and more. - Provides in-depth clinical reviews on the role of psychologists in pediatric subspecialties, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue concentrates on the current evidence and the collected experience of pediatric oncologists who care for cancer patients. The individual articles will provide the general pediatrician with a comprehensive primer on diagnosing and managing various types of cancers in the child with cancer. A cancer diagnosis is no longer a death sentence, so management and monitoring is very important and covered in every article.

Pediatricians in the Unites States and around the World continue to face a myriad of global health threats affecting child and adolescent health including: 1) infectious diseases of poverty [e.g. human immunodeficiency virus (HIV), tuberculosis, malaria, and neglected tropical diseases] in low-and middle-income countries (LMIC), especially in sub Saharan Africa; 2) emerging and reemerging infectious diseases (such as Ebola); 3) rise of non-communicable diseases (e.g. common mental disorders); 4) unintentional injuries; and 5) environmental health hazards (e.g. climate change). Despite the promising news about rapid declines in maternal and child mortality in the era of Millennium Development Goals (MDGs), which originated from the United Nation (UN) Millennium Declaration in 2000, only 20% and 7% of LMIC are currently on track to attain the maternal and child mortality targets. For example, 44% of deaths in children younger than 5 years occur in neonates. Besides discovery of life-saving interventions (e.g. development of new and improved vaccines) for maternal and child health, we also need to do a better job at bridging the knowledge-implementation gap and increase the effectiveness of proven interventions. For example, despite the availability of effective vaccines to prevent pneumococcal pneumonia, rotavirus gastroenteritis, and human papilloma virus-related diseases (e.g. cervical cancer), use of these vaccines remain suboptimal in LMIC. We need to recognize that global health is also local public health. For example, improving access, equity and quality of care for orphans and vulnerable children, immigrant and newly arrived refugee children in the U.S. remains a challenge. Timely access to psychiatric care for children and adolescents with mental illness is a major concern. The explosion of new age technology (such as the internet) also poses a considerable risk to children and adolescents. Pediatricians also need to be aware of diverse socio-cultural determinants of health and ethical issues in global health service and delivery.This issue of Pediatric Clinics of North America aims to address the above crucial global health challenges affecting children and adolescents. As practicing pediatricians, we have the unique opportunity to influence local and global public health. In the post-MDG era (beyond 2015), collaborative partnerships between various disciplines and across research, education and service is vital to reduce health inequities in children worldwide.