This comprehensive guide sheds new light on the benefits of FDG PET/CT in diagnosing inflammatory diseases. Although FDG PET/CT offers an invaluable tool for diagnosing inflammatory diseases, the clinical evidence on its application remains limited. To remedy this gap, each chapter of this book includes detailed descriptions of how FDG PET/CT can be used in connection with a specific inflammatory disease. Further, the authors discusses the precise clinical presentation, including key images and their interpretation, techniques and diagnosis. As such, it allows readers to see for themselves how valuable FDG PET/CT is for the diagnosis of cardiac sarcoidosis and aortitis syndrome, as well as rheumatic diseases and neuroimflammation, and the detection of the disease focus of inflammation or fever of unknown origin. Given its scope, this excellent collection is a valuable resource for radiologists and physicians who are involved in nuclear medicine, as well as cardiologists, cardiovascular surgeons, and rheumatologists.

This issue of PET Clinics focuses on FDG-PET/CT Imaging in Infectious and Inflammatory Disorders, and is edited by Drs. Soren Hess and Lars Gormsen. Articles will include: Patient preparation and patient related challenges in infectious/inflammatory disease; Systemic infections (Fever/bacteremia of unknown origin, immunocompromised patients); Infections in bone and prosthetic joints; The infected heart; Inflammatory bowel disease; Pulmonary inflammatory diseases (sarcoidosis including cardiac and COPD); Infection and inflammation imaging: Beyond FDG; Polymyalgia rheumatica; Low grade inflammation; Large vessel vasculitis; Tuberculosis; and more!

This pocket book provides clinicians with the necessary information to understand the role of FDG PET/CT in infection and inflammation. It will help both in making appropriate imaging requests with adequate clinical information and in interpreting the report. The coverage encompasses a wide range of topics, including the role of PET/CT in pyrexia of unknown origin, vasculitis, autoimmune diseases, prosthetic joint infections, osteomyelitis and diabetic foot, immunodeficiency disease, and vascular graft surgery. The book will be a very useful guide to a great test that can provide significant assistance in patient management. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, in which leading professionals succinctly explain the importance of nuclear medicine in the diagnosis and management of oncological and non-oncological conditions.

This book covers all aspects of PET-CT including newer applications involving infection and inflammation and basic information on PET-CT new tracers. It explains the approach, protocols and miscellaneous applications about various infections and inflammation that helps in its early and better diagnosis in multiorgan and multisystem involvements in routine clinical practice. Chapters provide systematic approach to the diagnosis of various infections such as bacterial, viral, tuberculosis, inflammatory pathologies and overlap in coexisting tumors and superadded/associated infections. This book offers assistance to medical practitioners in understanding various advantages of PET-CT in single scan as compared to different modalities for diagnosis as well as oncologists dealing with concurrent malignant and non-malignant conditions, students, and interns.

PET/CT holds great promise for the management of many types of infection and inflammation. This issue discusses many of these uses, starting with arthroplasty-associated infection. FDG PET/CT also has utility in inflammatory bowel disease. This issue also discusses the utilization of FDG PET and PET/CT in the evaluation of diabetic foot, and in monitoring therapeutic effect in patients without malignancy. PET/CT is reviewed regarding its use in patients with sarcoidosis or IgG4 disease. Also covered is the application of FDG PET/CT in detecting the source of fever of unknown origin. Artherosclerosis and vasculitis can be assessed by PET/CT and FDG PET/CT can also be used in the management of severe infection in patients with malignancies. Finally, the issue discusses the use of PET and PET/CT in the evaluation of osteomyelitis.

Thoroughly and systematically presents the state-of-the-art in the diagnostic uses of radiologic imaging and nuclear medicine in the diagnosis and management of infectious and inflammatory diseases Although our understanding of microorganisms has advanced significantly and antimicrobial therapy has become increasingly available, infection remains a major cause of patient morbidity and mortality. Imaging of infection and inflammation provides a classic example of radiology and nuclear medicine’s strengths as well as weaknesses in the discovery and diagnosis of disease. Fortunately, the weaknesses are subsiding as new studies and techniques point to better planning and precision in the use of single and combined imaging modalities. Diagnostic Imaging of Infections and Inflammatory Diseases: A Multidisciplinary Approach deals with the very latest developments in the use of radiologic techniques and modalities in the management of patients with a host of infectious and inflammatory diseases. Tremendously timely and useful, this innovative, multidisciplinary book covers a wide range of topics in three parts: PART 1: Infections and Host Response Epidemiology of Infections in the New Century Bacterial Osteomyelitis: the Clinician Point of View PART 2: Radiological Imaging Radiological Imaging of Osteomyelitis Radiological Imaging of Spine Infection Radiological Imaging of Soft Tissue Infections Radiological Imaging of Abdominal Infections and Inflammatory Disease Radiological Imaging of Vascular Graft Infection Radiological Imaging of TB and HIV PART 3: Nuclear Medicine Imaging Nuclear Medicine Imaging of Infections: Techniques, Acquisition Protocols, and Interpretation Criteria Nuclear Medicine Imaging of Osteomyelitis: WBC, Monoclonal Antibody, or Bacterial Imaging? Nuclear Medicine Imaging of Spondylodiscitis: The Emerging Role of PET Nuclear Medicine Imaging of Soft Tissue Infections Nuclear Medicine Imaging of Infections and Inflammatory Diseases of the Abdomen Nuclear Medicine Imaging of Vascular Graft Infections: The Added Role of Hybrid Imaging Nuclear Medicine Imaging of TB and HIV Nuclear Medicine Imaging of Fever of Unknown Origin Nuclear Medicine Imaging of Inflammatory Diseases Along with carefully developed clinical cases describing the management of patients with inflammation and infection, Diagnostic Imaging of Infections and Inflammatory Diseases is an ideal guide for radiologists and nuclear medicine physicians as well as clinical specialists from many other fields.

This book is a clinically oriented, up-to-date, and in-depth review of the various applications of FDG-PET/CT and PET/MR in cardiovascular diseases with emphasis on the current available evidence. Positron emission tomography (PET) imaging with fluorodeoxyglucose (FDG) has seen increased applications in cardiovascular diseases over the last decades. Its utility is already established in a wide range of conditions, including myocardial viability imaging, assessment of inflammatory diseases such as sarcoidosis and vasculitis, as well as imaging of infectious processes, such as infective endocarditis and cardiac implantable electronic device infection. In addition, there are several emerging indications such as the imaging of left ventricular assisting device infection and native valve endocarditis as well as new applications under investigation. The first section of the book reviews the technical basis of cardiovascular PET/CT and PET/MR imaging as well as cardiac metabolism. The following chapters each present specific pathologies, presenting epidemiology, pathophysiology, and diagnostic strategies, along with high quality clinical cases to support the discussion. The final chapter is a review of 15 interesting and clinically relevant cases. This is an ideal guide for nuclear medicine physicians, cardiologists, radiologists, residents, post-graduate fellows, and technologists.

This issue of PET Clinics is Part II of a two-part issue, and focuses on PET-CT-MRI Applications of Musculoskeletal Disorders. It is edited by Drs. Abass Alavi (the Consulting Editor of PET Clinics), Ali Salavati, Ali Gholamrezanezhad and Ali Guermazi. Articles will include:Applications of PET-CT-MR in the management of benign musculoskeletal disorders; Diagnostic management of primary and secondary spinal neoplastic disease: The role of PET-CT-MRI; Skeletal Metastasis Evaluation: Value and impact of PET/CT on Diagnosis, Management and Prognosis; Hybrid imaging (PET CT/PET MRI) of bone metastases; Diffusion-weighted MR Imaging in Evaluating Bone Metastases; Imaging of Osteoarthritis by Conventional Radiography, MRI, PET-CT and PET-MRI; Evolving Role of MRI and PET in Assessing Osteoporosis; Evolving Role of Novel PET-CT-MRI based quantitative technique for Assessing Muscle Disorders; Pediatric musculoskeletal applications of PET-CT-MRI; In vivo molecular imaging of inflammation and infection; Future perspective of the application of PET-CT-MRI in musculoskeletal disorders; and more!

This book offers a systematic coverage of diagnostic imaging in infectious and inflammatory diseases in musculoskeletal system. The first part is devoted to a general review of infectious diseases in musculoskeletal system, as well as pathogenic classification, imaging techniques, pathogenic and imaging characteristics. In the following parts, imaging interpretation of typical infectious and inflammatory diseases affecting bone, joint, and soft tissue is described. Each disease is clearly illustrated using cases combined with high-resolution CT, MRI and PET. The book provides a valuable reference source for radiologists and doctors working in the area of infectious and inflammatory diseases.

This issue of PET Clinics focuses on Recent Advances in Imaging with PET, CT, and MR Techniques and is edited by Drs. Habib Zaidi, Abass Alavi and Drew A. Torigian. Articles will include: Total-body PET imaging: Developments in instrumentation; Prospects for total-body PET imaging using plastic scintillators; Total-body imaging: Potential clinical applications; New challenges for PET image reconstruction for total-body imaging; Advances in preclinical PET instrumentation; Applications of hybrid PET/MRI in CNS disorders; Applications of hybrid PET-MRI in MSK disorders; Assessment of total body atherosclerosis burden by PET-CT; Recent advances on CT and MR imaging in radiology; Potential impact of Total Body PET imaging in measuring global disease burden in systemic inflammatory disorders; Applications of PET-MRI in CV disorders; and more!