A guide that assists diagnosis and therapeutic of neurological and psychiatric disorders. It includes an introductory chapter that covers basic neuroscience and pharmacology as they pertain to the treatment of central nervous system disorders.

A comprehensive, systematic, and advanced review of the scientific, preclinical, and clinical aspects of several major mental illnesses. The illnesses covered range from neurological disorders including Alzheimer's disease, Huntington's disease, and Parkinson's disease, to psychiatric disorders including schizophrenia, autism spectrum disorders, Tourette's syndrome and tic disorders, obsessive-compulsive disorder, unipolar depression, bipolar disorder, and attention deficit hyperactivity disorder. For each disorder, the authors uniformly discuss its incidence and prevalence, etiology, molecular targets and mechanisms of action, brain structures and pathways, animal models, signs and symptoms, genetics, treatments, and related medical terminology.

Covers symptoms and signs of disordered nervous function, their analysis in terms of anatomy and physiology, and their clinical implications. Also included are accounts of occurrences of the syndromes and descriptions of main categories and types of disease that express themselves by each syndrome.

Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book also offers a perspective on future studies on the treatment of neurological disorders. The beneficial effects of curcumin have been observed both in cultured cells and in animal models, thus paving the way for ongoing present and future human clinical trials. Curcumin produces antioxidant and anti-inflammatory effects not only by blocking oxidative stress and neuroinflammation in neurotraumatic and neurodegenerative diseases, but also by restoring cellular homeostasis and rebalancing redox equilibrium. Identifies molecular mechanisms of curcumin effects in neurological diseases Includes effects on neurotraumatic, neurodegenerative and psychiatric diseases Covers the antioxidant, anti-inflammatory and immunomodulatory effects of curcumin Examines curcumin’s potential in developing new therapeutic drugs

New from Oxford Textbooks in Psychiatry, the Oxford Textbook of Neuropsychiatry bridges the gap between general psychiatric textbooks and reference texts in neuropsychiatry. Divided into four sections, it covers core knowledge and skills for practice in all psychiatric disciplines, with key information for training in neuropsychiatry.

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

The gold-standard text that has defined neurology – updated for today’s practice in full color The definitive text on the full-spectrum of neurology for decades, Adams and Victor's provides the treatment and management strategies needed to confidently handle both common and rare neurologic conditions. Written in a clear, consistent tone, this classic resource will meet the needs of the seasoned professional or the aspiring clinician. Written from the perspective of the general neurologist, Adams and Victor's has been hailed as the most detailed, thorough, and authoritative text available on the subject. Adams and Victor's Principles of Neurology, Tenth Edition describes the various categories of neurologic disease and the main diseases that constitute each. Each subject is introduced by a detailed discussion of the symptoms and signs of disordered nervous function, their anatomic and physiologic bases, and their clinical implications. Adams and Victor's Principles of Neurology is logically divided into six parts: The Clinical Method of Neurology Cardinal Manifestations of Neurologic Disease Growth and Development of the Nervous System in the Neurology of Aging Major Categories of Neurologic Disease Diseases of the Spinal Cord, Peripheral Nerve, and Muscle Psychiatric Disorders The Tenth Edition is highlighted by the welcome addition of full-color photographs, expanded coverage of important subspecialties, and an increased number of tables and figures. Edition after edition, Adams and Victor's has stayed true to its original mission: to provide a well-written, readable text emphasizing a disciplined presentation of clinical data and lucid descriptions of underlying disease processes.

An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to deve

The definitive guide to the full spectrum of neurology "This is one of the best neurology textbooks available, providing the distilled insights and knowledge of some of today's truly outstanding neurologic clinicians....Like its predecessors, the current edition features writing that is clear and concise, yet conversational—it almost feels as if the reader is on rounds hearing the insights of a truly superb clinician....offers a great deal to the serious student of neurology and is well worth the investment. This outstanding text will continue to be a key resource for neurologists and neurosurgeons, as well as resident trainees in those disciplines. Many practicing internists, emergency physicians, and pediatricians will also find it to be an excellent resource."--JAMA A Doody's Core Title ESSENTIAL PURCHASE for 2011! 4 STAR DOODY'S REVIEW! "This book should be an essential element in the library of both young and seasoned clinicians....This has always been a successfully balanced textbook, combining a personal approach to the study of neurology and neurologic diseases. This edition, now 1572 pages, expands on the prior editions admirably. It achieves the difficult task of refreshing and updating a classic."--Doody's Review Service "one of the iconic texts in clinical medicine. The fact that it is now in its ninth edition attests to its durability and credibility as a comprehensive source for the pathophysiology, evaluation, and treatment of disorders of the nervous system. First published in 1975, it has withstood the enormous changes in neurological sciences during the subsequent decades and has remained a staple on the reference shelves of practitioners from a variety of backgrounds and training levels....A unique attribute for a volume of this size is that each chapter is written by the same authors, thus achieving a uniformity of voice....As a gold standard text, the ninth edition of Adams and Victor’s Principles of Neurology would serve as valuable complement to any medical library."--World Neurosurgery Journal Adams and Victor's Principles of Neurology provides all the information you will need to confidently handle any neurologic problem, from disorders of motility, and derangements of intellect, behavior, and language, to the degenerative and neuromuscular diseases. Having this gold standard text on your reference shelf is like being able to consult with skilled clinicians on a daily basis. More than a compilation of facts, Adams and Victor's delivers expert insights not found in any other resource that help you understand every aspect of neurological disease. Written in a conversational style, the text offers practical, yet in-depth, coverage of both common and rare illnesses. Adams and Victor's Principles of Neurology also includes timely, complete, and accessible treatment and clinical management strategies. FEATURES Balanced presentation of evidence-based research coupled with the perspectives and experience of world-renowned expert neurologists Logical six-part organization reviews the clinical method, cardinal presentations, diseases of the central nervous system, diseases of the peripheral nervous system, and psychiatric disorders A-to-Z coverage of cardinal manifestations, including disorders of the special senses; epilepsy and disorders of consciousness; disorders of energy, mood, autonomic, and endocrine functions; and neuromuscular, spinal cord, and psychiatric disease Focus on symptoms, etiology, diagnosis, and treatment offers complete, practical guidance in clinical practice Special section on growth, development, and aging related to neurologic disease presents the latest, cutting-edge research in this integral area