In an accessible style, this book provides a thorough examination of key concepts. Solubility, stability, rheology, surface & interfacial phenomena, micromeritics, & complexation are some of the basic qualities of drug substances discussed, and understanding them can help formulate medicinal substances into effective dosage forms. Further, the document incorporates the relevant ICH stability testing criteria and offers ideas for applicable practicals. The presentation is intended to inspire independent research because of its accessible language and emphasis on clarity over brevity

Buy E-Book of Physical Pharmaceutics-II (English Edition) Book For B.Pharm 4th Semester of U.P. State Universities

Physical Pharmacy is one of the important subjects for pharmacy students. The book on Physical Pharmaceutics is written with an idea to provide the coverage of subject in the manner of five chapters and the first chapter covers the different topic related to solubility of drug such as: solubility expression, salvation, raoult’s law and solubility of liquid with other forms of matters and gives a basic understanding of the physical properties of drug or pharmaceuticals. On the other the second chapter is dedicated to the states of matters and the properties of matter such as latent heat, eutectic mixture, liquid complexes and different types of solid states The third chapter is dedicated to the Micromeritics covering the topic of particle size distribution, particle shape and specific surface and derived properties of powder. Similarly, the fourth chapter describes the complexation and protein biding in details and fifth chapter specially talks about the pH buffers and isotonic solutions making this book a one stop solution for the readers of pharmaceuticals, it also contains other important topics of physical pharmaceuticals. This book is written in such a manner that a beginner or an expert in this field will easily understand the topic described in it and will reach to it learning goal

Buy E-Book of Physical Pharmaceutics-I (English Edition) Book For B. Pharm 3rd Semester of U.P. State Universities

We are very pleased to put forth the first edition of 'Laboratory Manual of Physical Pharmaceutics II'. This manual is prepared as per PCI Education Regulations, 2014 for Degree Course in Pharmacy. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, minimum theoretical background, resources used, procedure, precautions, observations, result, conclusion, references and related questions. A sincere attempt has been made through this manual to provide practical knowledge to the students related to various experiments in Physical Pharmaceutics II. The manual mainly includes the experiments through which the students will learn how the basic properties of drug like solubility, dissolution, can limit the bioavailability of drug and in turn the efficacy of the drug. The solubility enhancement techniques like reduction of particle size, use of solubilizing agents or prodrugs etc. are also discussed. The students will also learn about the importance of drug stability and how the parameters like temperature, pH, humidity and light can affect the drug stability. Physical pharmaceutics is very important subject which helps the researchers to design and formulate various dosage forms including its manufacturing aspects. The students will be proficient in handling various equipment used in physical pharmaceutics laboratory. The students will also be able to determine pKa, partition coefficient, surface tension, critical micelle concentration, HLB value, stability constant, buffer capacity, etc. in the laboratory. We have taken extra efforts to make the experiments simpler, easy to understand and perform. The graphs have also been provided wherever necessary. Each experiment is divided into sections like aim, practical significance, relevant course outcomes, practical skills, relevant affective domain related outcomes, practical outcomes, minimum theoretical background, requirements, related questions, and references. The manual has been designed with more emphasis on the practical skill improvement of the students so that the students can perform the practical with ease and comfort. We are very much thankful to the designer, publisher, printers and all the stakeholders for putting their efforts for successfully bringing this manual out for the students. Hope this manual will help the students to learn the concept, principles and perform the experiments. We wish them all the best!!!

Consistently revised and updated for more than 60 years to reflect the most current research and practice, Martin’s Physical Pharmacy and Pharmaceutical Sciences, 8th Edition, is the original and most comprehensive text available on the physical, chemical, and biological principles that underlie pharmacology and the pharmaceutical sciences. An ideal resource for PharmD and pharmacy students worldwide, teachers, researchers, or industrial pharmaceutical scientists, this 8th Edition has been thoroughly revised, enhanced, and reorganized to provide readers with a clear, consistent learning experience that puts essential principles and concepts in a practical, approachable context. Updated content reflects the latest developments and perspectives across the full spectrum of physical pharmacy and a new full-color design makes it easier than ever to discover, distinguish, and understand information—providing users the most robust support available for applying the elements of biology, physics, and chemistry in work or study.

Biochemistry, Biophysics, and Molecular Chemistry: Applied Research and Interactions provides the background needed in biophysics and molecular chemistry and offers a great deal of advanced biophysical knowledge. It emphasizes the growing interrelatedness of molecular chemistry and biochemistry, and acquaints one with experimental methods of both disciplines. This book addresses some of the enormous advances in biochemistry, particularly in the areas of structural biology and bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry. Topics include scientific integrity and ethics in the field; clinical translational research in cancer, diabetes, and cardiovascular disease; emerging drugs to treat neurodegenerative diseases; swine, avian, and human flu; the use of big data in artificial knowledge in the field; bioinformatic insights on molecular chemistry; and much more.