Extremophiles are organisms that are able to live in extreme conditions due to their unique physiological and genetic adaptations. Extremophiles are harnessed for their extremozymes that have wide applications in biotechnology, pharmaceutics, and industry. Recent developments in genomics and proteomics have helped unravel the mechanism of survival, physiological adaptation, and genomics structure of extremophiles. Physiology, Genomics, and Biotechnological Applications of Extremophiles covers innovative developments in understanding the physiology and biochemistry of extremophiles using the -omics perspective, focuses on the advancement in mechanisms of the extremophiles that makes them able to survive under extreme conditions, and discusses the applications of extremophiles in astrobiology. Covering topics such as genomics and the history and identification of extremophiles, it is ideal for students, professors, researchers, academicians, microbiologists, agricultural scientists, and biotechnologists.

This book covers the latest development in the biotechnological application of extremophiles. Along with this the impact of climate change and environmental pollution on loss of diversity of extremophiles is also discussed. This is crucial as the loss of this diversity is related with the loss of many bioactive compounds and bacteria of ecological importance.

Microbial Essentialism: An Industrial Prospective refers to properties specifically possessed by microbes such as secretion of metabolites which make them unique and can be employed by industries. These microorganisms can be commercially exploited for beneficial purposes such as the production of whole microbial cells or their products for direct use or as starting raw material in the manufacture of other commercial products which can contribute to large-scale and profit-oriented businesses. Microbial Essentialism: An Industrial Prospective reviews the newest techniques, approaches, and options in the use of microorganisms for the manufacture of industrially important products such as pharmaceuticals, industrial enzymes, chemicals, proteins, foods and beverages, and fuels. It covers fundamental principles of established and innovative industrial microbiology and biotechnology processes and products. It also discusses industrial microorganisms and the technology required for large-scale cultivation and isolation of fermentation products. Covers key aspects of microbial physiology, exploring the versatility of microorganisms and their diverse metabolic activities and products Provides methods and various traditional and novel applications of microorganisms to industrial processes Contributed by a multidisciplinary group of experts who offer not only a thorough evaluation of the primary literature, but also invaluable first-hand experience in industrial microbiology and biotechnology

In the evolving environment of bioinformatics, genomics, and computational biology, academic scholars are facing a challenging challenge – keeping informed about the latest research trends and findings. With unprecedented advancements in sequencing technologies, computational algorithms, and machine learning, these fields have become indispensable tools for drug discovery, disease research, genome sequencing, and more. As scholars strive to decode the language of DNA, predict protein structures, and navigate the complexities of biological data analysis, the need for a comprehensive and up-to-date resource becomes paramount. The Research Anthology on Bioinformatics, Genomics, and Computational Biology is a collection of a carefully curated selection of chapters that serves as the solution to the pressing challenge of keeping pace with the dynamic advancements in these critical disciplines. This anthology is designed to address the informational gap by providing scholars with a consolidated and authoritative source that sheds light on critical issues, innovative theories, and transformative developments in the field. It acts as a single reference point, offering insights into conceptual, methodological, technical, and managerial issues while also providing a glimpse into emerging trends and future opportunities.

Biotechnology of Microbial Enzymes: Production, Biocatalysis, and Industrial Applications, Second Edition provides a complete survey of the latest innovations on microbial enzymes, highlighting biotechnological advances in their production and purification along with information on successful applications as biocatalysts in several chemical and industrial processes under mild and green conditions. The application of recombinant DNA technology within industrial fermentation and the production of enzymes over the last three decades have produced a host of useful chemical and biochemical substances. The power of these technologies results in novel transformations, better enzymes, a wide variety of applications, and the unprecedented development of biocatalysts through the ongoing integration of molecular biology methodology, all of which is covered insightfully and in-depth within the book. This fully revised, second edition is updated to address the latest research developments and applications in the field, from microbial enzymes recently applied in drug discovery to penicillin biosynthetic enzymes and penicillin acylase, xylose reductase, and microbial enzymes used in antitubercular drug design. Across the chapters, the use of microbial enzymes in sustainable development and production processes is fully considered, with recent successes and ongoing challenges highlighted. - Explores advances in microbial enzymes from basic science through application in multiple industry sectors - Includes up-to-date discussions of metabolic pathway engineering, metagenomic screening, microbial genomes, extremophiles, rational design, directed evolution, and more - Provides a holistic approach to the research of microbial enzymes and their use in sustainable processes and innovation - Features all new chapters discussing microbial enzyme classes of growing interest, as well as enzymes recently applied in drug discovery and other applications

Physiological and Biotechnological Aspects of Extremophiles highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms of these fascinating organisms use to survive.The vast majority of extremophiles are microbes which include archaea, bacteria and some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation.Aimed at research scientists, students, microbiologists, and biotechnologists, this book is an essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology, bioprospecting, biomining, biofuels, and extremozymes of these organisms. - Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules from basic to applied research - Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles - Gives detailed and comprehensive insight about use of genetic engineering as well as genome editing for industrial applications

Biofuels and Sustainability: Life-cycle Assessments, System Biology, Policies, and Emerging Technologies presents the current progress and challenges related to the sustainability of biofuels. Addressing a wide range of issues, the book examines the methods and technologies, policies for sustainable biofuels, impacts of advanced fuels, recent advances, and future research prospects. Reflecting new developments, emphasis is given to new biological/biochemical approaches that offer the most efficient, cost-effective, and sustainable strategies for biofuel production. Divided into five parts, the first provides an overview of biofuels, the need for alternate fuels, carbon footprints, life cycle assessments, environmental aspects, various generations of biofuels, biofuel production from lignocellulosic material, and artificial intelligence in biofuel production. Part 2 examines the various methods and technologies for biofuels production, with case studies from the USA, UK, and Brazil. Part 3 explores the policies for sustainable biofuels, including current standards, with applications from the USA, European Union, Asia, and Africa. Part 4 analyses the impacts of advanced fuels in the decarbonization of transport, climate change mitigation, sustainable agriculture, and water resources, with perspectives from developed and developing countries. Finally, Part 5 critically reviews the recent advances and future research prospects related to termites, insects, metabolic engineering, microorganisms, and bioreactors. - Provides carbon footprints and lifecycle assessments of biofuel and bioproduct production from 2nd and 3rd generation feedstocks and compliance with the international standards - Highlights the emerging applications of systems biology in biofuel and bioenergy production, including biomimetics and protein engineering - Analyzes the sustainable production of biofuels at various stages, such as feedstock production, biomass pre-treatment and novel bioprospection - Explains the technological challenges of biofuel production, designing novel bioreactors, and value-added processing of biofuel residues - Discusses and analyses biofuel and bioenergy policies from various countries and various regions of the world

Improving and Tailoring Enzymes for Food Quality and Functionality, Second Edition covers the most relevant information demanded in the production, engineering, and application of enzymes. The title is very detailed and is in the important cross-field of academia and industry. This totally revised new edition covers a broad range of topics related to enzymes and their use in food, presenting both the fundamental theory and practical application, updated with interesting novel information on biosensors, waste, valorization, up-cycling and engineering perspectives, besides an increased focus on sustainability. - Thoroughly updated revision covering a broad range of topics related to enzymes and their use in the food industry - Presents both the fundamental theory and recent examples from the literature, including the fundamentals of protein folding and enzyme catalysis, the preparation of enzymes from natural and recombinant sources, immobilizing enzymes, and a range of specific food applications - Covers new research directions in enzymes, thus helping those trying to solve a technical issue or develop a new product

This contributed volume deals with the various aspects of freshwater microbiology including diverse habitats, associated microorganisms, their ecological interactions, and industrial applications. Freshwater ecosystems are dynamic natural resources, providing sources of potable water, food, animal habitats, and recreation. Perspectives of microbial dynamics in freshwater bodies, covered in this title, provide a comprehensive and systematic analysis of microbial ecology in these ecosystems. These microbes are at the hub of biogeochemical cycles (carbon, nitrogen, phosphorus, potassium, and other elements). Moreover, they are an integral part of the aquatic food web and control the quality of freshwater bodies. Chapters in this title also discuss the issue of pollution in freshwater bodies and put forward available strategies for eco-friendly solutions. The book is a perfect documentation of primary and secondary data-based information on the latest research findings, case studies, experiences, and innovations in the field of freshwater microbiology. The book is of great use to students, researchers, and professionals studying aquatic sciences.