Biomedical Innovations to Combat COVID-19 provides an updated overview on the development of vaccines, antiviral drugs and nanomaterials, and diagnostic methods for the fight against COVID-19. Perspectives on such technologies are identified, discussed, and enriched with figures for easy understanding and applicability. Furthermore, it contains basic aspects of virology, immunology, and antiviral drugs that are needed to fully appreciate these innovations. This book is split into four sections: introduction, presenting basic virologic and epidemiological aspects of COVID-19; vaccines against COVID-19, discussing their different types and applications used to develop them; diagnostic approaches for SARS-CoV-2, encompassing advanced sensing and microfluidic-based biosensors; and drug development and delivery, where antivirals based on nanomaterials or drugs are presented. It is a valuable source for virologists, biotechnologists, and members of biomedical field interested in learning more about how novel technologies can be applied to fasten the eradication of the COVID-19 and similar pandemics. - Presents updated literature coverage summarizing the most relevant information on COVID-19 - Written by experts from diverse scientific domains in order to provide readers with a thorough view on the subject - Encompasses tables, figures and information trees especially developed for the book in order to condense and highlight key points for quick reference

Smart Nanomaterials to Combat the Spread of Viral Infections comprises nanotechnology-based approaches with detailed preventive and treatment methodology for enabling their application in antiviral systems. This book discusses the role of metal nanoparticles in the treatment of and prevention of viral infections and nanotechnology advancements in antiviral coatings to combat affected surfaces. It also covers the use of nanomaterials for the efficient intracellular delivery of antiviral agents to disinfect and treat viral infections. This is a timely coverage of how nanotechnologies and materials as well as the utilization of artificial intelligence and Internet of things–based smart nano-systems are used to control and manage viral infections during the COVID-19 pandemic. Advances in smart research and future antimicrobial applications round out the book. This book provides a comprehensive overview of smart nanomaterials and advanced nano-system applications to researchers and academics in virology, microbiology, chemistry, material science, nanotechnology, and biotechnology as well as those in industries interested in their virucidal properties to prevent viral infections. - Encompasses the novel synthesis of nanostructures and cost-effective nanosystems from functional hybrid materials with special emphasis on their effective virucidal properties being biocompatible and economic - Examines mechanisms of advanced nanomaterials as effective virucidal agents in disinfectants, coatings, treatment, and preventive approaches - Discusses possible advancements and upcoming smart research in antimicrobial applications - Offers timely coverage of SARS-CoV-2 pandemic management strategies

Viral Infections and Antiviral Therapies provides comprehensive coverage of viral infections and their transmission. Coverage includes antiviral agents, therapeutics, their mechanisms and treatment strategies. The book is organized into four sections, including an introduction to antiviral therapies, viral infections and their transmission, antiviral agents and therapeutics, and a market overview and future developments. The chapters in each section of the book discuss various key topics that are contributed to by an international group of leading experts. - Covers emerging and sexually transmitted viruses, including mode of transmission and pathophysiology of viral infections - Describes antiviral agents and therapeutics for viruses such as rotaviruses, enteroviruses and coronaviruses - Discusses strategies for the delivery of antiviral agents and vaccinations

In the past two decades, several pandemics have ravaged the globe, giving us several lessons on infectious disease epidemiology, the importance of initial detection and characterization of outbreak viruses, the importance of viral epidemic prevention steps, and the importance of modern vaccines. Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment summarizes the improvements in the 21st century to overcome / prevent / treat global pandemic with future prospective. Divided into 9 chapters, the book begins with an in-depth introduction to the lessons learned from the first pandemic of the 21st century. It describes the history, present and future in terms of detection, prevention and treatment. Followed by chapters on the outbreak, treatment strategies and clinical management of several infectious diseases like MERS, SARD and COVID 19, Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment, presents chapters on immunotherapies and vaccine technologies to combat pandemic outbreak and challenges. The book finishes with a chapter on the current knowledge and technology to control pandemic outbreaks. All are presented in a practical short format, making this volume a valuable resource for very broad academic audience. Provides insight to the lessons learned from past pandemics Gives recommendations, future direction in terms of detection, prevention and treatment of pandemics Guides readers through the status and recent developments of vaccines to overcome or prevent pandemics Shows how to enhance the host innate immunity in infectious diseases Includes a chapter on immunotherapies to combat pandemic outbreaks

Unpacks the mysteries of COVID-19's origins to impart important lessons for future outbreaks. Unpacking the mysteries of COVID-19's origins to impart important lessons for future outbreaks. In this timely book, leading public health expert Laura H. Kahn uses the comprehensive One Health approach to investigate the COVID-19 pandemic. The concept of "One Health" recognizes the interconnected links among the health of humans, animals, plants, and the environment. By comparing the history, science, and clinical presentations of three different coronaviruses—SARS-CoV-1, MERS, and SARS-CoV-2 (COVID-19)—Kahn uncovers insights with important repercussions for how to prepare for and avoid future pandemics. The One Health approach is a useful framework for examining the outbreak of COVID-19. Understanding the origins of this zoonotic disease requires examining the environmental and molecular biological factors that allowed the virus to spread to humans. Kahn investigates the many ways in which the wild animal trade, wet markets, and the camel industry contributed to the spread of earlier coronaviruses such as SARS-CoV-1 and MERS. The book also explores the biosafety, biosecurity, and bioethics implications of gain-of-function research on pandemic potential pathogens. This important book is a must-read to understand the history, science, and geopolitics of the COVID-19 pandemic.

This open access book provides a comprehensive analysis of the socioeconomic determinants of Covid-19. From the end of 2019 until presently, the world has been ravaged by the Covid-19 pandemic. Although the cause of this is (obviously) a virus, the extent to which this virus spread, and therefore the number of infections and deaths, was largely determined by socio-economic factors. From this, it follows that the course of the pandemic varies greatly from one country to another. This observation applies both to countries’ resilience to such a pandemic (which is mainly rooted in the period preceding the outbreak of the virus) and to the way in which countries have reacted to the virus (including the political choices on how to respond). Meanwhile, research has made it clear that the nature of this response (e.g., elimination policy, mitigation policy, and proceeding herd immunity) was, on the one hand, strongly determined by political and ideological factors and, on the other hand, was highly influential in the factors of success or failure in combating the pandemic. The book focuses on the situation in a number of Western regions (notably the USA, the UK, and the EU and its Member States). The author addresses the reasons why in many Western countries both pandemic prevention and response policies to Covid-19 have failed. The book concludes with recommendations concerning the rearrangement of the socio-economic order that could increase the resilience of (Western) societies against such pandemics.

Since the start of the COVID-19 pandemic there have been remarkable research and innovation efforts to fight the SARS-COV-2 virus and the related disease. This patent landscape report provides early observations on the patenting activity which took place in the field of COVID-19 vaccines and therapeutics, and compares results with clinical trial data for related candidate vaccines and drugs.