This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

Polycystic ovary syndrome (PCOS) is one of the most common reproductive health problems of women. Despite this, its effective treatment remains a significant challenge to the medical profession. This second edition (published 2007) of a highly successful and well-reviewed book is a thorough update on the syndrome, its aetiology, pathology, impact on infertility, and effective medical management. Every chapter has been extensively referenced and completely revised and updated. New chapters cover: hyperinsulinemic insulin resistance; new treatments including in-vitro maturation; paediatric origins, including the Barker Hypothesis; adrenocortal dysfunction; polycystic ovary syndrome in non-western societies; surgical treatment of obesity associated with polycystic ovaries, and treatment with vitamins and minerals. The book is a reference text for all clinicians with an interest in reproductive endocrinology, including gynaecologists, IVF specialists and obstetricians.

Polycystic ovary syndrome (PCOS) is a classic female infertility condition affecting an estimated 6-10% of all women, many of whom are unaware of the problem. A disease that affects women from adolescence to menopause, PCOS is the single most common endrocrinologic abnormality affecting women. This book is an edited collection of writings that comprehensively covers the disease, from diagnosis and epidemiology of PCOS to clinical evaluation.

Clearly presented and thoroughly up to date, this important text provides an overview of current knowledge of the polycystic ovary syndrome (PCOS) - its etiology, pathology, and the implications for effective medical management. In contrast with existing titles, this book focuses on the difficulty in making an accurate diagnosis and the conseq

Providing a holistic, global approach to all aspects of PCOS, Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan offers authoritative guidance on the diagnosis, treatment, and management of this challenging syndrome. It presents a coherent, evidence-based approach to diagnosis, as well as recommendations for clinical practice grounded in recent advances in basic sciences. Unique in the field, this practical resource provides decision-making tools for endocrinologists, fertility specialists, gynecologists, and internists who diagnose and treat patients with this complex chronic condition. Covers all aspects of PCOS and management across the lifespan, including short- and long-term metabolic, endocrine, and psychological challenges. Offers an integrative approach to the understanding of pathophysiology and management of PCOS in adult women and adolescent girls with a focus on genetics, microRNAs, and risk factors. Includes clinical, hormonal and metabolic features as well as diagnostic criteria and PCOS phenotypes. Presents treatment and management options for common symptoms, hirsutism, menstrual irregularity, and conception planning, including a chapter on subfertility and the male PCOS equivalent. Includes coverage of standard comorbidities, as well as a section on global approaches to patients with PCOS that addresses unique concerns, practices, and stigmas associated with how different cultures approach the disorder. Addresses the use of complementary/alternative medicine, lifestyle modification, and behavioral therapy in managing PCOS. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Women's healthcare regarding polycystic ovarian syndrome remains challenging. Patients often go from one specialist to another trying to fully understand and management the disorder. Women often go years before a diagnosis, seeing three or more doctors before a confirmed diagnosis. Polycystic Ovarian Syndrome: Challenging Issues in the Modern Era of Individualized Medicine brings together multiple medical disciplines to improve the care of women with PCOS. Such a multidisciplinary clinical and scientific approach integrates obstetrics and gynecology, pediatric and medical endocrinology, internal medicine, genetics, psychology and laboratory medicine into relevant translational clinical and scientific discussions that update both the scientific understanding of PCOS and the diagnosis and management of all aspects of the syndrome. The impact of PCO on the onset of puberty is subdivided in sub sections to get a better understanding of this condition and the management at different stages in a woman's life. - Represents an unparalleled compilation of chapters from experts in the field relevant to contemporary polycystic ovarian syndrome - Covers aspects such as obesity, metabolic changes, and emotional changes associated with PCOS - Highlights contemporary management and the current understanding of this unique syndrome with a comprehensive and fresh approach

Now in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications of PCOS and by raising awareness of potential “ripple effects”, aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS (including but not limited to reproductive endocrinologists, gynecologists, family physicians, dermatologists, mental health professionals), for the aspiring women's health providers of tomorrow, and for the researchers who are striving to unravel the mysteries of the complex entity that PCOS is.

Our knowledge about infertility has expanded and improved significantly in recent years and Polycystic Ovary Syndrome (PCOS) is now recognised as a major cause. PCOS is a term which covers a variety of symptoms, and in this new volume the editors have compiled a wide ranging collection of studies dealing with diverse aspects of PCOS, including genetics, pathophysiology, cardiovascular effects, treatment required and long term consequences. Previous books on PCOS have been expensive high level, research oriented works. This new volume is different. All the chapters have been written with the student in mind. Obstetrics and gynaecology students need to know about PCOS and this book is an accessible comprehensive overview to the subject. It features contributors from around the world including Australia, Belgium, Chile, Egypt, Hong Kong, Hungary, India, Iran, Israel, Italy, Lebanon, Mexico, Netherlands, Nigeria, Saudi Arabia, Singapore, Thailand, Turkey, UK and USA.

Establishing an integrative approach to the understanding and management of PCOS Polycystic ovary syndrome (PCOS) is the most frequent disorder affecting women of reproductive age. Recent years have shown substantial advances in our understanding of the complex genetic, biochemical, metabolic, cardiovascular, and reproductive issues associated with PCOS. This book presents a comprehensive overview of recent clinical developments in identifying the phenotypic expression of women with PCOS resulting in a completely new recognition of its phenotypic variability. Metabolic and cardiovascular consequences of the syndrome are discussed in detail. Advances made in dealing with secondary forms of PCOS-like syndromes are presented as well as specific therapies of clinical manifestations and their outcomes. Additionally, a number of hot topics are included presenting genetic developments, endothelial causes leading to unfavorable outcomes, and novelties in therapeutic approaches dealing with metabolic and reproductive consequences. Covering phenotypic characteristics, diagnostic criteria, central pathophysiological mechanisms, metabolic, cardiovascular and reproductive aspects, and modern therapeutic approaches, this book is a useful tool for general practitioners, gynecologists, pediatricians, internists, endocrinologists, as well as cardiologists.

This Is An Important Condition In Gynecologic Practice. The Book Will Take Up Clinical Presentation, Diagnosis And Treatment Of The Disorder. The Book Is Contributory In Nature. This Book Will Be Useful For Postgraduate Students And Practicing Gynecologists