A hands-on guide to assist in the planning and execution of synthetic reactions in the laboratory Despite the maturity of organic chemistry, it can still be very challenging to identify optimal methods for synthetic transformations that perform as well in real-world manufacturing processes as they do in the laboratory. This detailed and accessible guide attempts to address this vexing issue and deliver proven methodologies practicing synthetic chemists will find valuable for identifying reaction conditions that work reliably over the broadest possible range of substrates. Practical Synthetic Organic Chemistry: Provides a practical guide to strategically planning and executing chemical syntheses for the bench chemist in industry Discusses information that is not common knowledge beyond the boundaries of process chemistry groups, such as the synthetic routes of selected contemporary pharmaceutical drugs and practical solvents, as well as green chemistry concepts Highlights key reactions, including substitutions, additions, eliminations, rearrangements, oxidations, and reductions Addresses basic principles, mechanisms, advantages and disadvantages of the methodology, and techniques for achieving laboratory success Incorporating such an extraordinary wealth of information on organic chemistry and its related fields into one complete volume distinguishes Practical Synthetic Organic Chemistry as an incomparable desktop reference for professionals and an invaluable study aid for students.

Diese Publikation ist ein Praktikerbuch für Organiker. Der Schwerpunkt liegt auf den Reaktionen, die am verlässlichsten und nützlichsten sind. Die Autoren der einzelnen Kapitel stellen Chemiker die Informationen zur Verfügung, die für die strategische Planung einer Synthese und Wiederholung der Verfahren im Labor notwendig sind. - Fasst alle wesentlichen Entwicklungen und Konzepte in einer Publikation zusammen und deckt die meisten der wichtigen Reaktionen in der organischen Chemie ab, u. a. Substitutions-, Additions-, Eliminierungsreaktionen, Umlagerung, Oxidation, Reduktion. - Behandelt die wichtigsten Reaktionen ausführlicher und zeigt die grundlegenden Prinzipien, Vor- und Nachteile der Methoden, Mechanismen und Techniken, um Reaktionen im Labor erfolgreich durchzuführen. - Mit neuen Inhalten zu den jüngsten Fortschritten in den Bereichen CH-Aktivierung, Photoredox-Katalyse und Elektrochemie, kontinuierliche chemische Prozesse und Anwendung der Biokatalyse in der Synthese. - Bietet überarbeitete Kapitel mit neuen und zusätzlichen chemischen Beispielen aus der Praxis.

The field of photocatalysis has developed rapidly over the last decade and it is time to clarify its impact on organic synthesis. This volume is an opportunity to provide the defining and current reference work for this field. A primary objective is to collect together the most useful, practical, and reliable methods for photocatalysis and to introduce them to a larger audience. The fundamental concepts of photophysics are introduduced and laboratory set-ups are described, enabling newcomers to the field to instantly apply these new tools in synthesis. Rather than aiming for comprehensive coverage, solutions for challenging transformations in synthesis applying visible light and suitable dyes are presented. A team of pioneers and leaders in the field has been assembled, who discuss both the practical and conceptual aspects of this rapidly growing field. Scope, limitations, and mechanism of the reactions are covered and key experimental procedures are included.