This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this area. Precision Medicine in Stroke provides a practical approach to each chapter, reinforcing clinical applications and presenting clinical cases. This book is intended for all clinicians that interact with stroke patients (neurologists, internal medicine doctors, general practitioners, neurosurgeons), students and basic researchers.

Authored by the world's foremost stroke experts, this classic text brings you fully up to date with current research findings and management approaches for cerebrovascular disease. Stroke: Pathophysiology, Diagnosis, and Management, 7th Edition, covers every aspect of this fast-moving field, and is an ideal resource for stroke specialists, general neurologists, and other medical professionals with an interest in stroke. You'll find expert clinical guidance, comprehensive pathophysiology coverage, data from recent trials, advances in diagnostic tests, full-color CT images, pathology slides, and much more, for a complete picture of today's stroke medicine. - Helps you recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. - Keeps you abreast of the overwhelming volume of studies and guidelines in this dynamic field, providing clear summaries and practical evaluations of all relevant data. - Contains updates throughout, including the latest clinical trials (thrombectomy, DAWN, DEFUSE), genetics research, prevention research, new therapies, and the new guidelines from the ASA. - Includes new slides for lectures, covering basic science, case studies, and interventional treatment overviews. - Features a Key Points summary at the beginning of each chapter so you can quickly find important information. - Provides abundant full-color CT images and pathology slides that help you make efficient and accurate diagnoses.

This book offers detailed guidance on the diagnostic use of cerebral angiography based on precise description of the angiographic appearances of normal anatomy and pathological conditions. In this third edition, every chapter has been thoroughly revised and enlarged to reflect new knowledge and experiences, and more attention is paid to the correlations between anatomopathological findings and clinical manifestations. Beyond explaining the diagnostic value of cerebral angiography, a key aim is to equip readers with the precise knowledge of the anatomy of cerebral vessels required for optimal application of endovascular therapy of pathologies involving the arteries and veins of the brain. As in preceding editions, the book is divided into two parts. The first part describes the normal anatomy, with attention to morphological aspects, embryological development, function, and vascular territories. The intraorbital and extracranial vascularization is also fully considered. The knowledge provided will serve as a sound basis for the correct interpretation of pathological processes and their clinical significance, as covered in depth in the second part of the book.

Increasing evidence suggests that particularly in high-risk patients, endovascular solutions offer substantial advantages compared to vascular surgical procedures. Nevertheless, growing numbers of procedures are associated with an increased incidence of complications. Knowledge of specific complications in different vessel areas will support the interventionist in preventing such adverse events and if necessary, provide considerable reassurance if such complications need to be resolved. In Complications in Peripheral Vascular Interventions, typical and atypical complications are described for all peripheral vessel areas, and methods for how to handle these events are outlined. The book is divided in two parts. Part 1 reviews general aspects on complications in peripheral interventions, and Part II covers the specific vessel areas. Each chapter on the specific vessel area includes Introduction to the frequency and kind of complications in this vessel area Factors identifying high-risk patients for these complications Complications of specific interventional steps and tools Endovascular techniques to resolve these complications Methods to avoid complications Summary Checklist for emergency equipment Offering practical tips for the interventionist in the cath lab, high-volume interventionists share their experiences by reviewing complicated cases and outlining different strategies used in real-life scenarios.

Offered in print, online, and downloadable formats, this updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors - Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong - head the sixth edition of this classic text, which is authored by the world's foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use. Combat stroke with the most comprehensive and updated multimedia resource on the pathophysiology, diagnosis, and management of stroke from leaders in the field