Up to 70% of oral cancers are preceded by premalignant oral lesions, such as persistent red or white patches in the mouth. Survival rates for oral cancer can be improved through early detection. It is therefore essential that oral health professionals such as dentists, dental hygienists, dental therapists, and oral health therapists understand the importance of conducting a thorough oral screening examination for malignant and potentially malignant lesions as part of their routine clinical assessments, even in younger populations considered at lower risk for oral cancer. Key features of the book include: laser treatment techniques ,human genome sequencing, early detection and multidisciplinary approach ,management strategies and mechanisms of proliferation and energy metabolism in oral cancer.

Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics: Volume Two: Diagnostic and Therapeutic Applications discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancers. It focuses on novel diagnostic techniques based on molecular biomarkers and their impact on treatment, covering different cancer types such as tumors in the nervous system, head and neck, oral and GI tractor, lung, breast, gastric system, leukemia and urogenital tract cancers. For each type, the book discusses the best diagnostic techniques and therapeutic approaches, thus helping readers easily identify the best solution for each case. This is a valuable resource for cancer researchers, oncologists, graduate students and other members of the biomedical field who are interested in the potential of biomarkers in cancer research. - Provides up-to-date information on current molecular biomarkers research for cancer - Presents new diagnostic techniques using biomarkers that can leverage quicker results that can be essential for patient's survivorship - Discusses several novel therapeutics applied to specific cancer types, such as head and neck, oral, GI tract, breast, lung and hepatocellular carcinomas

Head and neck cancer (HNC) is a heterogeneous group of cancers that, if combined, represent one of the most common cancer types. Patients with HNC suffer significant morbidity and mortality due to the importance of the structures involved. Over two-thirds of these patients are diagnosed at a late stage, leading to a poor prognosis. Therefore, advancements in early detection and treatment of HNC are crucial. Volume I begins with a general overview, including the industry landscape, of HNC detection, diagnosis, and treatment. Next, it covers the applications of innovative technologies such as microfluidics, nanotechnology, and deep learning to early detect as well as study HNC. For example, studying the cellular features at a single-cell level became possible with the advancement of technologies such as mass cytometry or specifically, Cytometry by Time Of Flight Mass Spectrometry (CyTOF), which has revolutionized the way we can study complex human diseases such as HNC. Finally, the last few chapters are dedicated to describing the standard of care of HNC. The first volume of Early Detection and Treatment of Head & Neck Cancers is highly pertinent to the next generation of interdisciplinary clinicians, scientists, residents, and students who are particularly interested in HNC and in the translation of early detection methods, technologies, and research to clinical practice.

This book identifies key treatment challenges and unique care considerations in patients with head and neck cancers, providing a comprehensive guide to patient management that illustrates the critical importance of a multidisciplinary approach in achieving optimal oncological, functional, and survival outcomes. It covers all relevant specialties, including dental and oral medicine, medical oncology, radiation oncology, surgical oncology, and reconstructive surgery. It highlights the vital role played by ancillary head and neck cancer services, such as speech and swallowing therapy, occupational and physical therapy, and nutritional therapy in offering essential physical and psychological support from the time of diagnosis onward. The closing chapters address post-treatment issues, including those relating to survivorship, surveillance, and end-of-life care. Multidisciplinary care is perhaps even more important for patients with head and neck cancers than for other cancer patients, and in addressing all its aspects this book is invaluable for a wide range of practitioners.

Cancer is the leading cause of mortality in most, if not all, countries around the globe. It is worth noting that the World Health Organisation (WHO) in 2019 estimated that cancer is the primary or secondary leading cause of death in 112 of 183 countries for individuals less than 70 years old, which is alarming. In addition, cancer affects socioeconomic development as well. The diagnostics of cancer are often carried out by medical experts through medical imaging; nevertheless, it is not without misdiagnosis owing to a myriad of reasons. With the advancement of technology and computing power, the use of state-of-the-art computational methods for the accurate diagnosis of cancer is no longer far-fetched. In this brief, the diagnosis of four types of common cancers, i.e., breast, lung, oral and skin, are evaluated with different state-of-the-art feature-based transfer learning models. It is expected that the findings in this book are insightful to various stakeholders in the diagnosis of cancer. ​

Each volume in the Early Detection and Treatment of Cancer Series is packed with practical, authoritative information designed to cover the full range of diagnostic procedures, including pathologic, radiologic, bronchoscopic, and surgical aspects. You’ll be able to determine the safest, shortest, least invasive way to reach an accurate diagnosis; stage the disease; and choose the best initial treatment for early stages. Based on current evidence in the literature, authors provide clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed to diagnose and stage each type of cancer. Practical, authoritative, and highly-illustrated, this volume in the brand new Early Detection and Treatment of Cancer series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for head and neck cancers. Apply expert advice on the best “next-step plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging. Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered. Better manage your patients with procedural video clips and more on the included CD-ROM. The small size and convenient format make this an ideal purchase for diagnostic reference. Outlines the steps after diagnosis to guide you through formulating a treatment or patient care plan. Emphasizes important points—such as the use of endoscopy in staging, chemoprevention, and promising gene therapies—with “key points boxes at the beginning of each chapter and pedagogic features throughout. Summarizes the process of accurately diagnosing and staging cancer in a logical, almost algorithmic, approach for easy reference. Discusses the treatment of early-stage disease so you have clear options for care. Complements the procedures outlined in the text with full-color photographs and line drawings to reinforce your understanding of the material. Features a CD-ROM showing video clips of diagnostic procedures, as well as all of the images, tables, and drawings from the text to help you better manage your patients.

This issue of Dental Clinics of North America focuses on Oral Cancer, and is edited by Drs. Eric Stoopler and Tom Sollecito. Articles will include: Evaluation and management of oral premalignant lesions; Oral cancer: genetics and the role of personalized medicine; Evaluation and staging of oral cancer; Adjunctive diagnostic techniques for oral cancer; Surgical management of oral cancer; Chemotherapy for oral cancer; Radiation therapy for oral cancer; Human papilloma virus (HPV) and oral cancer; Dental treatment planning for patients with oral cancer; Dental management of patients who have undergone oral cancer therapy; Impact of oral cancer on quality of life; and more!

Oral cancer is a common disease with a high incidence of morbidity and mortality. Despite technological advancements in diagnosis and treatment, the five-year survival rate is low. Researchers worldwide are attempting to identify new and novel methods for early diagnosis and better treatment of oral cancer to improve survival rate and quality of life post recovery. This book examines current concepts in oral cancer and emphasizes future perspectives for diagnosis and treatment of disease for better clinical outcomes and patient care.

This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.

In this book, clinicians and basic scientists from USA, India, and other countries discuss the rationales and clinical experiences with targeted approaches to treat, prevent, or manage cancer. Cancer is a hyperproliferative disorder that is regulated by multiple genes and multiple cell signaling pathways. Genomics, proteomics, and metabolomics have revealed that dysregulation of dozens of genes and their products occur in any given cell type that ultimately leads to cancer. These discoveries are providing unprecedented opportunities to tackle cancer by multi-faceted approaches that target these underpinnings. This book emphasizes a multi-targeted approach to treating cancer, the focus of the 5th International Conference on Translational Cancer Research that was held in Vigyan Bhawan, Delhi (India) from Feb 6-9, 2014.