Over the last quarter century or so, specialization within obstetrics and gynecology, and pediatrics has resulted in the development of the disciplines of maternal-fetal medicine and neonatology, respectively. A primary focus of maternal-fetal medicine has been to understand the mechanism(s) of premature delivery and develop treatment modalities for improving the length of gestation. A primary focus of neonatology has been to under stand the causes of respiratory distress in the neonate. Success has resulted, not only in the lengthening of gestation, but an improved understanding of the causes and treatment of neonatal respiratory disease. With increasing success has come the necessity to under stand the metabolic principles of the parturient, the fetal/placenta unit, and the neonate. These principles are clearly very important from multiple aspects. Increased understand ing of metabolism of the pregnant woman would explain the aberrations occurring in normal and abnormal pregnancy and improve nutritional support for the parturient. A prime example of altered metabolism is the parturient with diabetes. Understanding metabolism ofthe fetal/placenta unit is necessary to increase the probability that the fetus will be born appropriate for size irrespective of the gestational age. The various compo nents of neonatal metabolism are important, not only for understanding the changes in physiology and biochemistry occurring in the developing neonate, but the principles by which nutritional support should be provided.

Neonatal nutrition has a pivotal role in normal child development and is of even greater importance in the sick or premature neonate. This 2006 edition includes a comprehensive account of the basic science, metabolism and nutritional requirements of the neonate, and a greatly expanded number of chapters dealing in depth with clinical issues ranging from IUGR, intravenous feeding, nutritional therapies for inborn errors of metabolism, and care of the neonatal surgical patient. Evolving from these scientific and clinical aspects, the volume highlights the important long-term effects of fetal and neonatal growth on health in later life. In addition, there are very practical chapters on methods and techniques for assessing nutritional status, body composition, and evaluating metabolic function.

Innovations in technology and new therapies have changed the face of medicine in the last few decades. These include advances in fetal diagnosis (preimplantation genetics, chorionic villous sampling and amniocentesis), drugs that have been developed to treat unique conditions in neonates such as respiratory distress syndrome (surfactant) and pulmonary hypertension (inhaled nitric oxide), as well as technological advances and interventions resulting in diagnostic (ultrasounds and MRI) and therapeutic interventions (intrauterine transfusion to ECMO). Research in fertility treatments has resulted in test tube babies and cloned animals, and that has also fostered technological advances in diagnostic and therapeutic interventions.The primary purpose of Innovations in Neonatal-Perinatal Medicine is to highlight these innovations in technology and therapy that have not only changed the way doctors deliver care to fetus and neonate but also reduced neonatal mortality thereby saving millions of lives in the process. These issues are addressed by the authors who are experts in their respective fields. The book will be valuable not only to healthcare providers but also to educators and policy makers.

Offering the comprehensive, authoritative information needed for effective diagnosis, treatment, and management of sick and premature infants, Fetal and Neonatal Physiology, 6th Edition, is an invaluable resource for board review, clinical rounds, scientific research, and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into definitive guidance for today’s busy practitioner, focusing on the basic science needed for exam preparation and key information required for full-time practice. It stands alone as the most complete text available in this complex and fast-changing field, yet is easy to use for everyday application. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Contains new chapters on Pathophysiology of Genetic Neonatal Disease, Genetic Variants and Neonatal Disease, and Developmental Biology of Lung Stem Cells, as well as significantly revised chapters on Cellular Mechanisms of Neonatal Brain Injury, Neuroprotective Therapeutic Hypothermia, Enteric Nervous System Development and Gastrointestinal Motility, and Physiology of Twin-Twin Transfusion. Features 1,000 full-color diagrams, graphs and anatomic illustrations, 170+ chapters, and more than 350 global contributors. Includes chapters devoted to clinical correlation that help explain the implications of fetal and neonatal physiology, as well as clinical applications boxes throughout. Provides summary boxes at the end of each chapter and extensive cross-referencing between chapters for quick reference and review. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more.

Provide the best care possible with expert insight and clinically relevant coverage of the physiologic changes that occur throughout all major periods of the perinatal experience — prenatal, intrapartum, postpartum, and neonatal. Maternal, Fetal & Neonatal Physiology: A Clinical Perspective, 4th Edition gives you a solid foundation for assessment and therapeutic interventions, featuring an emphasis on the evolving interrelationships between mother, fetus, and neonate and adaptations of preterm and term infants to the extrauterine environment. - Solid coverage of the physiologic bases for assessment and therapeutic interventions make this an ideal resource for advanced practice. - Synthesis of the latest research studies and evidence-based practice provides vital data on normal physiologic changes during the antepartum, intrapartum and postpartum periods; anatomic and functional development of the fetus; and developmental physiology of preterm and term neonates. - Pharmacology tables offer quick access to key pharmacology information and drug effects with clinical examples. - Coverage of pathophysiology and interventions for the pregnant woman, fetus, and newborn for selected abnormal events provides a solid understanding of physiologic adaptations and developmental physiology relating to major body systems and metabolic processes. - Comprehensive tables, diagrams, and illustrations highlight important concepts and summarize key information - Thoroughly updated content offers the very latest evidence-based information, contemporary research, and clinical developments related to maternal, fetal, and neonatal physiology. - New coverage on the late pre-term infant provides the most current practice guidelines to promote quality care. - Expanded discussions of reproductive processes reflect cutting-edge research and the clinical implications of physiologic and genetic effects brought to bear from both the female and the male. - Extensive and reliable web sources allow for further study or checking for updated information. - New NICHD standard definitions on fetal monitoring enable you to identify fetal heart rate patterns using standardized nomenclature.

Provide the best care possible with expert insight and clinically relevant coverage of the physiologic changes that occur throughout all major periods of the perinatal experience - prenatal, intrapartum, postpartum, and neonatal. Maternal, Fetal & Neonatal Physiology: A Clinical Perspective, 4th Edition gives you a solid foundation for assessment and therapeutic interventions, featuring an emphasis on the evolving interrelationships between mother, fetus, and neonate and adaptations of preterm and term infants to the extrauterine environment. Solid coverage of the physiologic bases for assessment and therapeutic interventions make this an ideal resource for advanced practice. Synthesis of the latest research studies and evidence-based practice provides vital data on normal physiologic changes during the antepartum, intrapartum and postpartum periods; anatomic and functional development of the fetus; and developmental physiology of preterm and term neonates. Pharmacology tables offer quick access to key pharmacology information and drug effects with clinical examples. Coverage of pathophysiology and interventions for the pregnant woman, fetus, and newborn for selected abnormal events provides a solid understanding of physiologic adaptations and developmental physiology relating to major body systems and metabolic processes.Comprehensive tables, diagrams, and illustrations highlight important concepts and summarize key information Thoroughly updated content offers the very latest evidence-based information, contemporary research, and clinical developments related to maternal, fetal, and neonatal physiology. New coverage on the late pre-term infant provides the most current practice guidelines to promote quality care. Expanded discussions of reproductive processes reflect cutting-edge research and the clinical implications of physiologic and genetic effects brought to bear from both the female and the male. Extensive and reliable web sources allow for further study or checking for updated information. New NICHD standard definitions on fetal monitoring enable you to identify fetal heart rate patterns using standardized nomenclature.

Babies of women with diabetes are nearly five times more likely to be stillborn and almost three times more likely to die in the first three months. The incidence of gestational diabetes mellitus in the U.S. is high—between 3 and 7 percent—and rising. The condition is often complicated by other risk factors such as obesity and heart disease. The Textbook of Diabetes and Pregnancy presents a comprehensive review of the science, clinical management, and medical implications of gestational diabetes mellitus, a condition with serious consequences that is on the increase in all developed societies. This new edition supports the latest initiatives and strategies of the International Federation of Gynecology and Obstetrics (FIGO) and adds chapters on noncommunicable diseases, obesity, bariatric surgery, and epidemiology outside Western cultures. Written by a cadre of experts, the book provides a comprehensive, authoritative, and international view of gestational diabetes mellitus and will be invaluable to maternal-fetal medicine specialists, diabetologists, neonatologists, and a growing number of gynecologists and general physicians concerned with the management of noncommunicable diseases in pregnancy.

Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors. 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place. In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.

Pregnancy complicated by preexisting diabetes can be managed through expert protocols and patient partnerships. Based on the new American Diabetes Association recommendations, this revised edition widely expands on the fourth edition. Topics include: pre-pregnancy counseling, contraception, psychological impact, morning sickness, nutritional management, insulin, diagnostic testing and surveillance, gestational diabetes, neonatal care of infants, and postpartum follow-up.

The leading resource for collaborative critical care for newborns, Merenstein & Gardner’s Handbook of Neonatal Intensive Care, 7th Edition provides a multidisciplinary approach and a real-world perspective. It focuses on evidenced-based practice, with clinical directions in color for easy retrieval and review. Special features help you prioritize the steps in initial care, and provide a guide to sharing information with parents. With each chapter written jointly by both physicians and nurses, this book is comprehensive enough to suit the needs of the entire team in your neonatal intensive care unit. Unique! A multidisciplinary perspective is provided by an editorial team of two physicians and two nurses, and each chapter is written and reviewed by a physician and nurse team, so information mirrors the real-world experience in a neonatal intensive care unit. Unique! Clinical content is in color, so you can quickly scan through chapters for information that directly affects patient care. Unique! Parent Teaching boxes highlight the relevant information to be shared with a patient’s caregivers. Critical Findings boxes outline symptoms and diagnostic findings that require immediate attention, helping you prioritize assessment data and steps in initial care. Coverage in clinical chapters includes pathophysiology and etiology, prevention, data collection, treatment, complications, outcomes, prognosis, and parent education. Expanded Neonatal Surgery chapter covers all of the most common procedures in neonatal surgery. Follow-up of the Neonatal Intensive Care Unit Infant chapter is expanded to include coverage of outcomes management and discharge planning. Streamlined references are updated to include only the most current or classic sources.