No leading university department of mathematics or statistics, or library, can afford to be without this unique text. Leading authorities give a unique insight into a wide range of currently topical problems, from the mathematics of road networks to the genomics of cancer.

Mathematical Theory of Probability and Statistics focuses on the contributions and influence of Richard von Mises on the processes, methodologies, and approaches involved in the mathematical theory of probability and statistics. The publication first elaborates on fundamentals, general label space, and basic properties of distributions. Discussions focus on Gaussian distribution, Poisson distribution, mean value variance and other moments, non-countable label space, basic assumptions, operations, and distribution function. The text then ponders on examples of combined operations and summation of chance variables characteristic function. The book takes a look at the asymptotic distribution of the sum of chance variables and probability inference. Topics include inference from a finite number of observations, law of large numbers, asymptotic distributions, limit distribution of the sum of independent discrete random variables, probability of the sum of rare events, and probability density. The text also focuses on the introduction to the theory of statistical functions and multivariate statistics. The publication is a dependable source of information for researchers interested in the mathematical theory of probability and statistics

Social life of bacteria is in the focus of recent research. Bacteria are simple enough to be accessible by science, but still complex enough to show cooperation, division of labor, bet-hedging, cross-talk and synchronized activities, and a rich variety of social traits. A central question of evolutionary theory is the explanation why this social life did develop, and why these systems are evolutionary stable. This book introduces the reader into the theory of evolution, covering classical models and as well as recent developments. The theory developed is used to represent the up-to-date understanding of social bacteria.This book will be useful for students and lecturers interested in mathematical evolutionary theory, as well as for researchers as a reference.

A definitive account of the origins of modern mathematical population genetics, first published in 2000.

Proceedings of a Conference held in Heidelberg, September 10 - 14, 1984

Experiencing the New Genetics will lead scholars and general readers alike to question how far genetic inheritance affects our selves and our future.

This book, suitable for numerate biologists and for applied statisticians, provides the foundations of likelihood, Bayesian and MCMC methods in the context of genetic analysis of quantitative traits. Although a number of excellent texts in these areas have become available in recent years, the basic ideas and tools are typically described in a technically demanding style and contain much more detail than necessary. Here, an effort has been made to relate biological to statistical parameters throughout, and the book includes extensive examples that illustrate the developing argument.

The scope of this book is the field of evolutionary genetics. The book contains new methods for simulating evolution at the genomic level. It sets out applications using up to date Monte Carlo simulation methods applied in classical population genetics, and sets out new fields of quantifying mutation and selection at the Mendelian level. A serious limitation of Wright-Fisher process, the assumption that population size is constant, motivated the introduction of self regulating branching processes in this book. While providing a short review of the principles of probability and its application and using computer intensive methods whilst applying these principles, this book explains how it is possible to derive new formulas expressed in terms of matrix algebra providing new insights into the classical Wright-Fisher processes of evolutionary genetics. Also covered are the development of new methods for studying genetics and evolution, simulating nucleotide substitutions of a DNA molecule and on self regulating branching processes. Components of natural selection are studied in terms of reproductive success of each genotype whilst also studying the differential ability of genotypes to compete for resources and sexual selection. The concept of the gene is also reviewed in this book, and it provides a current definition of a gene based on very recent experiments with micro-array technologies. A development of stochastic models for simulating the evolution of model genomes concludes the studies in this book. Deserving of a place on the book shelves of workers in biomathematics, applied probability, stochastic processes and statistics, as well as in bioinformatics and phylogenetics, it will also be relevant to those interested in computer simulation, and evolutionary biologists interested in quantitative methods.