Probability, Statistics and Modelling in Public Health consists of refereed contributions by expert biostatisticians that discuss various probabilistic and statistical models used in public health. Many of them are based on the work of Marvin Zelen of the Harvard School of Public Health. Topics discussed include models based on Markov and semi-Markov processes, multi-state models, models and methods in lifetime data analysis, accelerated failure models, design and analysis of clinical trials, Bayesian methods, pharmaceutical and environmental statistics, degradation models, epidemiological methods, screening programs, early detection of diseases, and measurement and analysis of quality of life.

Disease Modelling and Public Health, Part A, Volume 36 addresses new challenges in existing and emerging diseases with a variety of comprehensive chapters that cover Infectious Disease Modeling, Bayesian Disease Mapping for Public Health, Real time estimation of the case fatality ratio and risk factor of death, Alternative Sampling Designs for Time-To-Event Data with Applications to Biomarker Discovery in Alzheimer's Disease, Dynamic risk prediction for cardiovascular disease: An illustration using the ARIC Study, Theoretical advances in type 2 diabetes, Finite Mixture Models in Biostatistics, and Models of Individual and Collective Behavior for Public Health Epidemiology. As a two part volume, the series covers an extensive range of techniques in the field. It present a vital resource for statisticians who need to access a number of different methods for assessing epidemic spread in population, or in formulating public health policy. - Presents a comprehensive, two-part volume written by leading subject experts - Provides a unique breadth and depth of content coverage - Addresses the most cutting-edge developments in the field - Includes chapters on Ebola and the Zika virus; topics which have grown in prominence and scholarly output

This book deals with the mathematical aspects of survival analysis and reliability as well as other topics, reflecting recent developments in the following areas: applications in epidemiology; probabilistic and statistical models and methods in reliability; models and methods in survival analysis, longevity, aging, and degradation; accelerated life models; quality of life; new statistical challenges in genomics. The work will be useful to a broad interdisciplinary readership of researchers and practitioners in applied probability and statistics, industrial statistics, biomedicine, biostatistics, and engineering.

Methods for estimating sparse and large covariance matrices Covariance and correlation matrices play fundamental roles in every aspect of the analysis of multivariate data collected from a variety of fields including business and economics, health care, engineering, and environmental and physical sciences. High-Dimensional Covariance Estimation provides accessible and comprehensive coverage of the classical and modern approaches for estimating covariance matrices as well as their applications to the rapidly developing areas lying at the intersection of statistics and machine learning. Recently, the classical sample covariance methodologies have been modified and improved upon to meet the needs of statisticians and researchers dealing with large correlated datasets. High-Dimensional Covariance Estimation focuses on the methodologies based on shrinkage, thresholding, and penalized likelihood with applications to Gaussian graphical models, prediction, and mean-variance portfolio management. The book relies heavily on regression-based ideas and interpretations to connect and unify many existing methods and algorithms for the task. High-Dimensional Covariance Estimation features chapters on: Data, Sparsity, and Regularization Regularizing the Eigenstructure Banding, Tapering, and Thresholding Covariance Matrices Sparse Gaussian Graphical Models Multivariate Regression The book is an ideal resource for researchers in statistics, mathematics, business and economics, computer sciences, and engineering, as well as a useful text or supplement for graduate-level courses in multivariate analysis, covariance estimation, statistical learning, and high-dimensional data analysis.

A new edition of the definitive guide to logistic regression modeling for health science and other applications This thoroughly expanded Third Edition provides an easily accessible introduction to the logistic regression (LR) model and highlights the power of this model by examining the relationship between a dichotomous outcome and a set of covariables. Applied Logistic Regression, Third Edition emphasizes applications in the health sciences and handpicks topics that best suit the use of modern statistical software. The book provides readers with state-of-the-art techniques for building, interpreting, and assessing the performance of LR models. New and updated features include: A chapter on the analysis of correlated outcome data A wealth of additional material for topics ranging from Bayesian methods to assessing model fit Rich data sets from real-world studies that demonstrate each method under discussion Detailed examples and interpretation of the presented results as well as exercises throughout Applied Logistic Regression, Third Edition is a must-have guide for professionals and researchers who need to model nominal or ordinal scaled outcome variables in public health, medicine, and the social sciences as well as a wide range of other fields and disciplines.

A timely and applied approach to the newly discovered methods and applications of U-statistics Built on years of collaborative research and academic experience, Modern Applied U-Statistics successfully presents a thorough introduction to the theory of U-statistics using in-depth examples and applications that address contemporary areas of study including biomedical and psychosocial research. Utilizing a "learn by example" approach, this book provides an accessible, yet in-depth, treatment of U-statistics, as well as addresses key concepts in asymptotic theory by integrating translational and cross-disciplinary research. The authors begin with an introduction of the essential and theoretical foundations of U-statistics such as the notion of convergence in probability and distribution, basic convergence results, stochastic Os, inference theory, generalized estimating equations, as well as the definition and asymptotic properties of U-statistics. With an emphasis on nonparametric applications when and where applicable, the authors then build upon this established foundation in order to equip readers with the knowledge needed to understand the modern-day extensions of U-statistics that are explored in subsequent chapters. Additional topical coverage includes: Longitudinal data modeling with missing data Parametric and distribution-free mixed-effect and structural equation models A new multi-response based regression framework for non-parametric statistics such as the product moment correlation, Kendall's tau, and Mann-Whitney-Wilcoxon rank tests A new class of U-statistic-based estimating equations (UBEE) for dependent responses Motivating examples, in-depth illustrations of statistical and model-building concepts, and an extensive discussion of longitudinal study designs strengthen the real-world utility and comprehension of this book. An accompanying Web site features SAS? and S-Plus? program codes, software applications, and additional study data. Modern Applied U-Statistics accommodates second- and third-year students of biostatistics at the graduate level and also serves as an excellent self-study for practitioners in the fields of bioinformatics and psychosocial research.

Explains the role of statistics in improving the quality of collecting and analyzing information for a wide variety of applications. The book examines the function of statisticians in quality improvement. It discusses statistical process control, quality statistical tables, and quality and warranty; quality standards in medicine and public health; Taguchi robust designs and survival models; and more.

Health services are often fragmented along organizational lines with limited communication among the public health–related programs or organizations, such as mental health, social services, and public health services. This can result in disjointed decision making without necessary data and knowledge, organizational fragmentation, and disparate knowledge development across the full array of public health needs. When new questions or challenges arise that require collaboration, individual public health practitioners (e.g., surveillance specialists and epidemiologists) often do not have the time and energy to spend on them. Smart Use of State Public Health Data for Health Disparity Assessment promotes data integration to aid crosscutting program collaboration. It explains how to maximize the use of various datasets from state health departments for assessing health disparity and for disease prevention. The authors offer practical advice on state public health data use, their strengths and weaknesses, data management insight, and lessons learned. They propose a bottom-up approach for building an integrated public health data warehouse that includes localized public health data. The book is divided into three sections: Section I has seven chapters devoted to knowledge and skill preparations for recognizing disparity issues and integrating and analyzing local public health data. Section II provides a systematic surveillance effort by linking census tract poverty to other health disparity dimensions. Section III provides in-depth studies related to Sections I and II. All data used in the book have been geocoded to the census tract level, making it possible to go more local, even down to the neighborhood level.

A modern and accessible guide to the analysis of introductory time series data Featuring an organized and self-contained guide, Time Series Analysis provides a broad introduction to the most fundamental methodologies and techniques of time series analysis. The book focuses on the treatment of univariate time series by illustrating a number of well-known models such as ARMA and ARIMA. Providing contemporary coverage, the book features several useful and newlydeveloped techniques such as weak and strong dependence, Bayesian methods, non-Gaussian data, local stationarity, missing values and outliers, and threshold models. Time Series Analysis includes practical applications of time series methods throughout, as well as: Real-world examples and exercise sets that allow readers to practice the presented methods and techniques Numerous detailed analyses of computational aspects related to the implementation of methodologies including algorithm efficiency, arithmetic complexity, and process time End-of-chapter proposed problems and bibliographical notes to deepen readers’ knowledge of the presented material Appendices that contain details on fundamental concepts and select solutions of the problems implemented throughout A companion website with additional data fi les and computer codes Time Series Analysis is an excellent textbook for undergraduate and beginning graduate-level courses in time series as well as a supplement for students in advanced statistics, mathematics, economics, finance, engineering, and physics. The book is also a useful reference for researchers and practitioners in time series analysis, econometrics, and finance. Wilfredo Palma, PhD, is Professor of Statistics in the Department of Statistics at Pontificia Universidad Católica de Chile. He has published several refereed articles and has received over a dozen academic honors and awards. His research interests include time series analysis, prediction theory, state space systems, linear models, and econometrics. He is the author of Long-Memory Time Series: Theory and Methods, also published by Wiley.