Guest editor Terence K. Trow has assembled an expert team of authors on the topic of Pulmonary Arterial Hypertension. Articles include: Epidemiology of Pulmonary Arterial Hypertension, Pathology of Pulmonary Hypertension, Genetics of Pulmonary Arterial Hypertension, Diagnosis of Pulmonary Arterial Hypertension, Pulmonary Hypertension Owing to Left Heart Disease, Pulmonary Hypertension due to Lung Disease and/or Hypoxia, Pulmonary Arterial Hypertension Associated with Congenital Heart Disease, World Health Organization Group 5 Pulmonary Hypertension, and more!

This issue of Clinics in Chest Medicine, guest-edited by Dr. Aaron B Waxman and Dr. Inderjit Singh, is focused on Pulmonary Hypertension. Topics discussed in this issue include but are not limited to: Integrative omics to characterize and classify pulmonary vascular disease, Contemporary Pharmacotherapeutic Approach in Pulmonary Arterial Hypertension, Personalized Medicine: The Future Management of Pulmonary Hypertension Requires A New Taxonomy, Sex differences in Pulmonary Hypertension and Pulmonary Hypertension in Pregnancy

This issue of Clinics in Chest Medicine, guest-edited by Dr. Margaret Pisani, is focused on Gender and Respiratory Disease. Topics discussed in this issue include but are not limited to: What are sex and gender and how can we study their impact in respiratory disease?, Sex differences in respiratory physiology, Impact of gender on social determinants of health, Gender differences in obstructive sleep apnea, Impact of gender on sleep disorders across the lifespan, Differences between men and women with COPD, Women and Lung Cancer, Pulmonary considerations in pregnant women and Asthma in women-gender specific considerations.

This issue of Clinics in Chest Medicine, edited by Drs. Peter Marshall and Wassim Fares, focuses on Pulmonary Embolism, with topics including: Clinical Probability Tools for DVT, PE, & Bleeding; Prevention of DVTs and Pulmonary Emboli: General Measures and High-Risk Populations; Diagnosis of DVTs and PEs: New Imaging Tools and Modalities; Perfusion Defects Misdiagnosed as Pulmonary Emboli; The Vicious Cycle of Hypercoagulability and Pulmonary Hypertension; VTE in Special Populations; Preganncy and Thrombo-embolic Disease; Challenges and Changes to the Management of PE in the Emergency Department; The Value of Bedside Echocardiogram in the Setting of Acute & Chronic Pulmonary Embolism; Management of Low-Risk PE; Update on the 'Novel' and Direct Oral Anticoagulants; Risk Stratification: Definitive/Aggressive Treatment of Hemodynamically Stable but Intermediate Risk Patients; Pulmonary Embolism Response Team (PERT); Surgical and Other Interventions for DVTs; IVC Filters; Catheter-Based Therapies of Pulmonary Emboli; Surgical-Based Therapies for PEs; and Chronic Thrombo-embolic Pulmonary Hypertension (CTEPH).

In this issue of Clinics in Chest Medicine, guest editors Drs. Luis Angel and Stephanie M. Levine bring their considerable expertise to the topic of Lung Transplantation. Top experts in the field cover key topics such as difficult decisions to transplant patients who are older, frail, underweight and obese; organ donation and variability in conversion to lung transplantation; conventional and novel approaches to immunosuppression; acute rejection and chronic allograft dysfunction; and more. - Contains 14 relevant, practice-oriented topics including COVID-19 and lung transplantation; the lung transplant candidate: indications, timing and selection criteria; bilateral lung transplantation vs. single lung transplant: complications, quality of life, and survival; critical care management of the lung transplant recipient; and more. - Provides in-depth clinical reviews on lung transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Chest Medicine, guest editors Drs. Erick Forno and Gregory Sawicki bring their considerable expertise to the topic of Pediatric Respiratory Disease. Top experts discuss COVID-19 in pediatric populations; environmental exposures and pediatric respiratory disease; genetics and genomics in childhood respiratory diseases; microbiome and metabolome: their role in pediatric respiratory disease; and more. Contains 21 relevant, practice-oriented topics including sickle cell disease and the lung; pediatric lung transplantation; health equity and advocacy in pediatric pulmonology; pediatric pulmonology in low-middle income countries; childhood interstitial lung diseases; primary cilliary dyskinesia; and more. Provides in-depth clinical reviews on pediatric respiratory disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Clinics in Chest Medicine, edited by Dr. Denis O'Donnell and Dr. Alberto Neder, focuses on Clinical Respiratory Physiology. Articles include: The Pathophysiology of Obstructive Sleep Apnea; The Physiology of Mechanical Ventilation; Exercise Pathophysiology in Congestive Heart Failure; Control of Breathing; Breathing at Extremes; Exercise Pathophysiology in Interstitial Lung Disease; Importance of Physiology in Clinical Decision-Making in the ICU; Pulmonary Hypertension and Exercise; Physiologic Effects of Oxygen Supplementation During Exercise in COPD; Benefits and Pitfalls of DLCO measurements in Clinical Practice; Cardio-pulmonary Interactions in COPD-CHF; Exercise Physiology in COPD; Dyspnea of Unknown Origin: The Role of Exercise Testing; Assessment of Ventilatory Limitation During Exercise; Respiratory Muscle Assessment in Clinical Practice; Exertional Periodic Breathing in Heart Failure; and Strategies to Increase Physical Activity in Chronic Respiratory Diseases

The guest editors for this issue, Talmadge King, Harold Collard, celebrated pulmonary specialists from UCSF, and Luca Richeldi, renowned visiting professor to UCSF from University of Modena, Italy, bring together a state-of-the-art issue on the important topic of Interstitial Lung Diseases (ILD). This comprehensive issue reviews the approach to diagnosis of ILD, radiology if ILD, pathology of ILD. Idiopathic pulmonary fibrosis is discussed, including phenotypes and comorbidities, acute exacerbation and accelerated decline, management, and pathobiology of novel approaches to therapy. Connective Tissue ILD, Chronic Hypersensitivity Pneumonitis, familial ILD and smoking-related ILD, and non-specific interstitial pneumonia are reviewed. In the final article, lung transplantation is discussed.

Drs. Robert Kotloff and Francis McCormack have assembled an expert team of authors on the topic of Rare and Orphan Lung Diseases. Articles include: Lymphangioleiomyomatosis, Pulmonary Lymphangiomatosis, Langerhans Cell Histiocytosis and other Histiocytic Diseases of the Lung, Pulmonary Alveolar Proteinosis, Pulmonary Alveolar Microlithiasis, Primary Ciliary Dyskinesia, Birt-Hogg-Dube Syndrome, Hermansky-Pudlak Syndrome, Hereditary Hemorrhagic Telangiectasia, Non-CF Bronchiectasis, Eosinophilic Lung Diseases, Benign Metastasizing Leiomyomata, and more!

This issue of Clinics in Chest Medicine is Guest Edited by Kristina Crothers, MD from the University of Washington and will focus on HIV and Respiratory Disease. Article topics include Abnormalities in Host Defense, Antiretroviral Therapy and Lung Immunology, HIV associated Pneumonia, HIV associated Tuberculosis, HIV associated lung malignancies, and HIV associated COPD.