Handbook of Reagents for Organic Synthesis Reagents, Auxiliaries and Catalysts for C-C Bond Formation Robert M. Coates and Scott E. Denmark The University of Illinois, Urbana, USA Recognising the critical need for bringing a handy reference work that deals with the most popular reagents in synthesis to the laboratory of practising organic chemists, the Editors, of the acclaimed Encyclopedia of Reagents for Organic Synthesis (EROS) have selected the most important and useful reagents employed in contemporary organic synthesis. The Handbook of Reagents for Organic Synthesis; Reagents Auxiliaries and Catalysts for C-C Bond Formation, provides practical and concise information on a diverse group of reagents. To familiarise the user with the spectrum of reagents contained within this volume, the editors have subdivided more than 200 entries into 22 classes based on their chemical structures and function. The articles, arranged alphabetically, contain all of the information found in EROS as well as expanded reagents listings. In addition, new listings of recently published review articles and monographs are included, as well as relevant Organic Syntheses procedures that deal with either the preparations or reactions of the featured reagents. This comprehensive and well referenced handbook will prove of great value to all practitioners in the field of organic chemistry.

Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used. Comprehensive information on 226 reagents Covers 64 reagents which were not included in EROS All information in one easy to use volume – at an affordable price All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros

Fiesers' Reagents for Organic Synthesis provides an up-to-date, A-to-Z listing of reagents cited in synthetic literature. • Covers, in volume 28, chemical literature and methodologies from July 2011 - December 2012 • Features entries with concise descriptions, illustrations of chemical reactions, selected examples of applications • Includes author indexes and subject indexes • Offers practical information on making/buying reagent, its usefulness, where to find complete details

Fiesers' Reagents for Organic Synthesis provides an up-to-date, A-to-Z listing of reagents cited in synthetic literature. • Covers, in volume 29, chemical literature and methodologies from 2013-mid 2014 • Features entries with concise descriptions, illustrations of chemical reactions, selected examples of applications • Includes author indexes and subject indexes • Offers practical information on reagents’ usefulness, where to find complete details

From reviews of previous volumes: "Essential for chemistry collections at the university and research levels." -New York Public Library "Highly recommended...lots of succinct, practical information on recent developments...in a format that is easy to use. The reagents are taken up in alphabetical order (common usage names, not CAS indexing code names), sometimes several to a page, sometimes several pages to a reagent. One can expect to find how to make the reagent (in loose terms), or where it can be bought, what is is good for, and where to seek complete details. As with previous volumes, one can profit from just browsing, even if one does not feel a need to look up any particular subject. It is thus a secondary function of the book to help one keep abreast of the field, and it would be a rare chemist who would not learn something new and useful from a casual perusal of the pages." -Journal of the American Chemical Society

The highly successful Fieser & Fieser series has provided several generations of professional chemists and students with an up-to-date survey of the reagent literature. Reagents are listed in alphabetical order by common name, and the brief entry tells how to make it or buy it, what it is good for, and where to find complete details. Volume 26 covers chemical literature from the middle of 2008 to the end of 2009.

The highly successful Fieser & Fieser series has provided several generations of professional chemists and students with an up-to-date survey of the reagent literature. Reagents are listed in alphabetical order by common name, and the brief entry tells how to make it or buy it, what it is good for, and where to find complete details. Volume 25 covers chemical literature from the beginning of 2007 to the end of June 2008.

This volume presents recent progress on 3d base metal catalyzed C-C cross coupling reactions. The contributions provide detailed discussions on the use of cheap metal catalysts such as Cr, Mn, Fe, Co, Ni, Cu, and Zn to construct Csp2-Csp2, Csp2-Csp3 and Csp3-Csp3 bonds with a variety of substrates. These non-noble metal catalyst have many advantages such as being inexpensive, having low toxicity and are environmentally benign. Therefore the use of cheap metal catalysts in organic synthesis has gained much attention in efforts to develop more sustainable synthetic green chemistry. Each chapter is written by international experts in the field and is a great resource for students, researchers and chemists working in industry to gain an overview on the latest developments.

The highly successful Fieser & Fieser series has provided several generations of professional chemists and students with an timely survey of the reagent literature. Providing an up-to-date, A-to-Z listing of reagents cited in synthetic literature, Fiesers' Reagents for Organic Synthesis, Volume 27 encompasses chemical literature from the end of 2009 to the end of 2011. Listed by common name, each entry feature a concise description, illustrations of chemical reactions, selected examples of applications, how to make it or buy it, what it is good for, and where to find complete details.

TheprototypicalcatalyticreductiveC-Cbondformations,theFischer-Tropsch reaction [1] and alkene hydroformylation [2], were discovered in 1922 and 1938, respectively [3,4]. These processes, which involve reductive coupling to carbon monoxide, have long been applied to the industrial manufacture of commodity chemicals [5]. Notably, alkene hydroformylation, also known as the oxo-synthesis, has emerged as the largest volume application of homo- neous metal catalysis, accounting for the production of over 7 million metric tons of aldehyde annually. Despite the impact of these prototypical reductive C-C bond formations, this ?eld of research lay fallow for several decades. Eventually, the increased availability of mild terminal reductants, in part- ular silanes, led to a renaissance in the area of catalytic reductive C-C bond formation.Forexample,the'rstcatalyticreductiveC-Ccouplingsbeyond- droformylation, which involve the hydrosilylative dimerization of conjugated dienes [6-12], appeared in 1969 - approximately 16 years after the ?rst - ported metal-catalyzed alkene hydrosilylation [13]. Following these seminal studies, the ?eld of catalytic reductive C-C bond formation underwent exp- sivegrowth,culminatingintheemergenceofanevergrowingbodyofresearch encompassing a powerful set of transformations. To our knowledge, no thematic volumes devoted solely to metal-catalyzed reductive C-C bond formationhave been assembled. For the ?rst time, in this issue of Topics in Current Chemistry,wepresent acompilation ofmonographs from several leaders in this burgeoning area of research. This collection of reviews serves to capture the diversity of catalytic reductive C-C couplings presently available and, in turn, the remarkable range of reactivity embodied by such transformations. There is no indication that this ?eld has reached its zenithanditisthehopeofthepresentauthorthatthisvolumewillfuelfurther progress.