This book eases the task of converting research work into a manuscript, and covers the recent developments in publishing that often stump budding researchers. Few researchers in the biomedical sciences are trained in the essential skills of reporting their results, and they seek help in writing a paper that will be acceptable for publication in the ‘right’ journal, and in presenting their results ‘effectively’ at a meeting. As well as covering the basic aspects of preparing manuscripts for publication, the book discusses best practices and issues relating to the publication of biomedical research, including topics such as peer-review, authorship, plagiarism, conflicts of interest, publication misconduct, electronic publishing and open-access journals. With more than two decades of experience in conducting workshops on writing scientific papers, the editors have brought together the expertise of 29 authors from seven countries to produce this one-stop guide to publishing research in biomedical sciences. This book is intended for young researchers who are beginning their careers and wish to hone their skills and understand the rigors of research writing and publishing.

Research in the Biomedical Sciences: Transparent and Reproducible documents the widespread concerns related to reproducibility in biomedical research and provides a best practices guide to effective and transparent hypothesis generation, experimental design, reagent standardization (including validation and authentication), statistical analysis, and data reporting. The book addresses issues in the perceived value of the existing peer review process and calls for the need for improved transparency in data reporting. It reflects new guidelines for publication that include manuscript checklists, replication/reproducibility initiatives, and the potential consequences for the biomedical research community and societal health and well-being if training, mentoring, and funding of new generations of researchers and incentives for publications are not improved. This book offers real world examples, insights, and solutions to provide a thought-provoking and timely resource for all those learning about, or engaged in, performing and supervising research across the biomedical sciences. - Provides a "big picture perspective on the scope of reproducibility issues and covers initiatives that have potential as effective solutions - Offers real-world research context for transparent, reproducible experimental design, execution and reporting of biomedical research with the potential to address aspects of the translational gap in drug discovery - Highlights the importance of reproducibility and the necessary changes in biomedical and pharmaceutical research training and incentives to ensure sustainability

The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated into the text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.

In an information and knowledge society, access to information and knowledge is a basic human right, making equitable and fair access to information and knowledge paramount. Open Access (OA) plays a huge role in addressing inequities as well as broad-based and inclusive scientific progress. On the surface, the number of publications discussing OA issues from various angles are on the rise. However, what is missing is a comprehensive assessment of the extent of OA implementation and a discussion of how to proceed in integrating OA issues from various perspectives. The Handbook of Research on the Global View of Open Access and Scholarly Communications articulates OA concepts and issues while demystifying the state-of-the-art knowledge domain in the areas of OA and scholarly communications from diverse perspectives as well as implications for the information and knowledge society. Covering topics such as ethics, copyright challenges, and open access initiatives, this book is a dynamic resource for publishers, librarians, higher education administrators, policymakers, students and educators of higher education, researchers, and academicians.

We live in an unprecedented era of flourishing of scientific publishing. However, many professionals in the biomedical sciences find writing articles to be a daunting task. The book is meant to serve as a practical writing guide that covers the writing process from the project's inception until online distribution of the published article.The book covers the framework for constructing a scientific study into a coherent narrative that can later be easily translated into a written manuscript. The content of each article section in accordance with the IMRAD format is covered and many details for the construction of additional submission materials are provided. Characteristics of papers reporting on specific types of research are presented as well as article types other than the general full research article. The book is full of resources for additional reading and learning.There are many writing guides on the market. Most of them are general, cover a wide range of scientific writing, and are mainly aimed at students. This book is best suited for young professionals who are a few years out of school. They no longer enjoy the benefit of close mentoring by a thesis adviser or equivalent, but still lack the experience to lead writing projects on their own. Through her experience of teaching young professionals and editing their work, Dr Diskin has learned their unique set of needs and the book has been written in an attempt to address them. Dr Diskin addresses the reader in the second person, with an ever-supportive tone. Importantly, the practicalities of writing articles in today's interconnected environment are discussed throughout the book. Topics such as coordinating the writing in a multinational team, use of different types of software in the writing process and resources available online to support the writer are addressed in detail.Related Link(s)

"The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge and find examples that will help them in their own work." -Maria Freire, Foundation for the National Institutes of Health Handbook of Biomarkers and Precision Medicine provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government, academia, teaching hospitals, biotechnology and pharmaceutical companies share best practices, examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists, students and decision makers engaged in Biomarker and Precision Medicine-centric drug development. Features: Detailed insights into biomarker discovery, validation and diagnostic development with implementation strategies Lessons-learned from successful Precision Medicine case studies A variety of exciting and emerging biomarker technologies The next frontiers and future challenges of biomarkers in Precision Medicine Claudio Carini, Mark Fidock and Alain van Gool are internationally recognized as scientific leaders in Biomarkers and Precision Medicine. They have worked for decades in academia and pharmaceutical industry in EU, USA and Asia. Currently, Dr. Carini is Honorary Faculty at Kings’s College School of Medicine, London, UK. Dr. Fidock is Vice President of Precision Medicine Laboratories at AstraZeneca, Cambridge, UK. Prof.dr. van Gool is Head Translational Metabolic Laboratory at Radboud university medical school, Nijmegen, NL.