This book highlights recent advances in the pathogenicity, mycotoxin-producing ability, and industrial application of members belonging to the genus Aspergillus. It is divided into two sections and six chapters that address different aspects and the importance of Aspergilli in relation to Aspergillus–human interactions, immunopathogenesis of invasive aspergillosis, the role of aflatoxin in Aspergillus flavus resilience to stress, mycovirus-containing A. flavus and carcinogenesis beyond mycotoxin production, and industrial application of Aspergillus species in conjunction to nanoparticle synthesis. This book brings readers several cutting-edge aspects of Aspergillus research with useful information for mycologists, microbiologists, toxicologists, plant pathologists, and pharmacologists, who may be interested in understanding the impact, significance, and recent advances within the genus Aspergillus that have not been critically noticed elsewhere.

Aflatoxins are a group of polyketide mycotoxins that are produced mainly by members of the genus Aspergillus. Production of these toxic secondary metabolites is closely related to fungal development (Keller et al., 2005; Jamali et al., 2012). Contamination of food, feed and agricultural commodities by aflatoxins poses enormous economic and serious health concerns because these chemicals are highly carcinogenic and can directly influence the structure of DNA. The resulting genetic defects can lead to fetal misdevelopment and miscarriages; aflatoxins are also known to suppress immune systems (Razzaghi-Abyaneh et al., 2013). In a global context, aflatoxin contamination is a constant concern between the 35N and 35S latitude where developing countries are mainly situated. With expanding boundaries of developing countries, aflatoxin contamination has become a persistent problem to those emerging areas (Shams-Ghahfarokhi et al., 2013). The continuing threat by aflatoxin contamination of food, feed and agricultural commodities to the world population has made aflatoxin research one of the most exciting and rapidly developing study areas of microbial toxins. The present research topic includes six review articles, three mini reviews and four original research articles. Contributors highlight current global health issues arising from aflatoxins and aflatoxigenic fungi and cover important aspects of aflatoxin research including contamination of crops, epidemiology, molecular biology and management strategies. Special attention is given to fungus-plant host interactions, biodiversity and biocontrol, sexual recombination in aflatoxigenic aspergilli, potential biomarkers for aflatoxin exposure in humans and safe storage programs.

The Editorial Office of Frontiers in Plant Science would like to thank all the Chief Editors, Associate Editors and Review Editors that played an integral part in Frontiers’ innovative Collaborative Peer-Review process in 2020. In particular, we would like to recognize and thank Prof. Joshua L. Heazlewood – our now former Field Chief Editor, for his commitment, support and enthusiasm for the Plant Science field. Josh’s dedication and leadership has helped Frontiers in Plant Science become the most cited journal in the field with a strong editorial community. Looking forward, we’re excited to welcome Prof. Yunde Zhao, as our new Field Chief Editor in 2021. Having been with Frontiers in Plant Science since 2017, Yunde has contributed extensively to the development of the journal and will continue to ensure the journal goes from strength to strength.

Aflatoxins are a naturally occurring carcinogenic byproduct of common fungi on grains and other crops, particularly maize and groundnuts. They pose a significant public health risk in many tropical developing countries and are also a barrier to the growth of domestic and international commercial markets for food and feed. In recent years the aflatoxin problem has garnered greatly increased attention from both policy and donor communities around the globe. What can be done to reduce the detrimental impacts of aflatoxins? Because growth of the molds that produce aflatoxins is caused by multiple factors, and because they must be controlled along the entire value chain from production to consumption, only a robust multifaceted approach to controlling aflatoxins is likely to be effective. The nineteen briefs in this set thus provide different perspectives on aflatoxin risks and solutions. The analyses fall under four broad themes: (1) what is known about the health risks from aflatoxins; (2) how to overcome market constraints to improved aflatoxin control by building new market channels and incentives; (3) what is the international policy context for taking action in developing countries; and (4) what is the state of research on new aflatoxin control technologies, including new methods for aflatoxin detection, crop breeding, biological control, food storage and handling, and postharvest mitigation. These briefs collectively provide a much clearer picture of the state of current efforts at combatting aflatoxins. They also identify what gaps loom particularly large—including the need for contry-specific risk analysis and for testing integrated solutions for the entire supply chain—in our global efforts to effectively reduce human exposure to aflatoxins and increase the economic returns to smallholders in agriculture.

This report reveals that substantial knowledge is available about the aflatoxin challenge that plagues African farmers, other agri-entrepreneurs, and governments. Commissioned by the ACP-EU Technical Centre for Agricultural and Rural Cooperation (CTA) in collaboration with the African Union Commission - Partnership for Aflatoxin Control in Africa (PACA), this literature review reveals that a wide range of commodities that are traded nationally, regionally and internationally are contaminated by aflatoxins. African citizens and economies are negatively impacted as a result.

Aflatoxin is a poisonous substance produced by a fungus, Aspergillus flavus, that occurs naturally in soils of cultivated and non-cultivated areas. The fungus commonly produces the toxin in maize, groundnut, and other staple grains and vegetables, and is especially prevalent in Africa. When animals consume feed contaminated with aflatoxin, milk and (at very low levels) meat, fish and eggs, can also be contam-inated. This note brings together recent research from the CGIAR and others on technologies for aflatoxin control in Africa and provides recommendations for catalyzing their adoption.

This Edited Volume Mycotoxins - Impact and Management Strategies is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of Mycotoxicology. The book comprises of single chapters authored by various researchers and edited by an expert active in this research area. This book is divided into three sections. Section 1 consists of one chapter that gives an overview of the socioeconomic impact of mycotoxins. Section 2 has five chapters that address the prevention and control of aflatoxins both at pre- and post-harvest stages. Section 3 has two chapters that deal with health impact and control in the poultry industry. This publication aims at providing a thorough overview of the latest research efforts in the field and opens new possible research paths for further novel developments in addressing the problem of mycotoxins.