This book explores ways in which creative research practice can be explicitly and mindfully geared to make a difference to the quality of social and ecological existence. It offers a range of examples of how different research methods can be employed (and re-tuned) with this intention. The book suggests that what Romm names "active" research involves using the research space responsibly to open up new avenues for thinking and acting on the part of those involved in the inquiry and wider stakeholders. The book includes a discussion of a range of epistemological, ontological, methodological and axiological positions (or paradigms) that can be embraced by inquirers implicitly or explicitly. It details the contours of an epistemology where knowing is recognized to be grounded in social relations, as a matter of ethics. While focusing on discussing the “transformative paradigm” and attendant view of research ethics, it considers to what extent the borders between paradigms can be treated as being permeable in creative and active inquiries. Apart from considering options for enhancing responsible research practice during the process of inquiry (and reconsidering mixed-research designs) the book also considers options for responsible theorizing that is inspirational for pursuing goals of social and ecological justice.

This Open Access book aims to present practical contributions to the ethics governance framework, the conceptualization and characteristics of ethics tools, as well as the experience gained from their application in different institutions. Its main objective is to provide a practical and useful guide that will help other institutions to start introducing Research Ethics effectively in their organizations. The European initiative ETHNA System has designed an ethics governance framework that can be implemented following specific guidelines and tools that can help different types of institutions to promote and generate responsible research and innovation. The papers included in this book were organized in topical sections as follows: foundations; experiences and lessons learned; ethics tools in practice; and looking into the future: main challenges.

This Open Access book builds on the experiences of one of the largest European projects in the domain of responsible Research and Innovation: NewHoRRIzon. It highlights the potential of and opportunity in responsible R&I to conduct innovation in a socially responsible way. Employing the methodology of Social Labs, the book analyses responsible R&I from an experience-based viewpoint and further explores the application of responsible R&I beyond scholarly and industrial interests. The contributors analyze the current European R&I landscape, provide reflection and reconceptualization of its core concepts, and project future challenges in relation to responsible R&I. The book complements the readers' line of work by providing insights on how responsible R&I can be applied by the audience, for example, in their decision-making processes.

This Open Access book is a guide to good, responsible research at each step of the process of research discovery, so that a researcher at the beginning of a scientific career has a clear pathway to doing good research and producing reliable results.The textbook will give context to the practices described in the European Code of Conduct for Research Integrity, guided by the fundamental principles or research integrity – reliability, honesty, respect, and accountability. Although we base the book on the European Code, the principles are the same in the global research community, such as those outlined in Fostering Integrity in Research from the US National Academies; Engineering and Medicine. The chapters in the book follow good research practices, give practical advice and address basic principles. In this way, the book is applicable to different research fields. It directs readers to various sources for further and updated information, particularly drawing from the resources available at The Embassy of Good Science, the European platform for research integrity and ethics.

The editors (of U. Hospitals of Cleveland and Rx Trials, Inc.) offer a guide to the practical and ethical issues in the conduct of clinical research coordinators that places the topic in broad international perspective by including approaches from the European Union, Japan, Canada, and the United States. Thirteen chapters discuss ethics and human subjects protection, responsible conduct, the informed consent process, pediatric informed consent and assent, study implementation and start-up, recruitment and retention of research subjects, documentation, quality assurance in clinical trials, communication, education and training, and future trends in professionalization. Distributed in the US by BookMasters. Annotation :2006 Book News, Inc., Portland, OR (booknews.com).

This open access book offers a unique and practically oriented study of organisational and national conditions for implementing Responsible Research Innovation (RRI) policies and practices. It gives the reader a thorough understanding of the different aspects of RRI, and of barriers and drivers of implementation of RRI related policies. It shows how different organisational and national contexts provide unique challenges and opportunities for bringing RRI into practice. The book provides concrete examples and offers the reader both a theory-based understanding of the topic, as well as guidance for action. The target audience encompasses, in addition to RRI students and scholars in particular, all students and scholars in the field of Science and Technology Studies (STS). The book is also of interest to students and scholars in the fields of research ethics, philosophy of science, organisational governance in the research system and organisational theory more generally. Finally, the book is of use to practitioners in research conducting and funding organisations working to implement RRI.

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

When 18-year-old Jesse Gelsinger died in a gene transfer study at the University of Pennsylvania, the national spotlight focused on the procedures used to ensure research participants' safety and their capacity to safeguard the well-being of those who volunteer for research studies. Responsible Research outlines a three-pronged approach to ensure the protection of every participant through the establishment of effective Human Research Participant Protection Programs (HRPPPs). The approach includes: Improved research review processes, Recognition and integration of research participants' contributions to the system, and Vigilant maintenance of HRPPP performance. Issues addressed in the book include the need for in-depth, complimentary reviews of science, ethics, and conflict of interest reviews; desired qualifications for investigators and reviewers; the process of informed consent; federal and institutional oversight; and the role of accreditation. Recommendations for areas of key interest include suggestions for legislative approaches, compensation for research-related injury, and the refocusing of the mission of institutional review boards. Responsible Research will be important to anyone interested in the issues that are relevant to the practice of using human subjects as research participants, but especially so to policy makers, research administrators, investigators, and research sponsorsâ€"but also including volunteers who may agree to serve as research participants.

The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.