Within the last fifty years the performance requirements for technical objects and systems were supplemented with: customer expectations (quality), abilities to prevent the loss of the object properties in operation time (reliability and maintainability), protection against the effects of undesirable events (safety and security) and the ability to

Safety and Reliability – Theory and Applications contains the contributions presented at the 27th European Safety and Reliability Conference (ESREL 2017, Portorož, Slovenia, June 18-22, 2017). The book covers a wide range of topics, including: • Accident and Incident modelling • Economic Analysis in Risk Management • Foundational Issues in Risk Assessment and Management • Human Factors and Human Reliability • Maintenance Modeling and Applications • Mathematical Methods in Reliability and Safety • Prognostics and System Health Management • Resilience Engineering • Risk Assessment • Risk Management • Simulation for Safety and Reliability Analysis • Structural Reliability • System Reliability, and • Uncertainty Analysis. Selected special sessions include contributions on: the Marie Skłodowska-Curie innovative training network in structural safety; risk approaches in insurance and fi nance sectors; dynamic reliability and probabilistic safety assessment; Bayesian and statistical methods, reliability data and testing; oganizational factors and safety culture; software reliability and safety; probabilistic methods applied to power systems; socio-technical-economic systems; advanced safety assessment methodologies: extended Probabilistic Safety Assessment; reliability; availability; maintainability and safety in railways: theory & practice; big data risk analysis and management, and model-based reliability and safety engineering. Safety and Reliability – Theory and Applications will be of interest to professionals and academics working in a wide range of industrial and governmental sectors including: Aeronautics and Aerospace, Automotive Engineering, Civil Engineering, Electrical and Electronic Engineering, Energy Production and Distribution, Environmental Engineering, Information Technology and Telecommunications, Critical Infrastructures, Insurance and Finance, Manufacturing, Marine Industry, Mechanical Engineering, Natural Hazards, Nuclear Engineering, Offshore Oil and Gas, Security and Protection, Transportation, and Policy Making.

This book reviews and presents several approaches to advanced decision-making models for safety and risk assessment. Each introduced model provides case studies indicating a high level of efficiency, robustness, and applicability, which allow readers to utilize them in their understudy risk-based assessment applications. The book begins by introducing a novel dynamic DEMATEL for improving safety management systems. It then progresses logically, dedicating a chapter to each approach, including advanced FMEA with probabilistic linguistic preference relations, Bayesian Network approach and interval type-2 fuzzy set, advanced TOPSIS with spherical fuzzy set, and advanced BWM with neutrosophic fuzzy set and evidence theory. This book will be of interest to professionals and researchers working in the field of system safety and reliability and postgraduate and undergraduate students studying applications of decision-making tools and expert systems.

Safety and Reliability of Complex Engineered Systems contains the Proceedings of the 25th European Safety and Reliability Conference, ESREL 2015, held 7-10 September 2015 in Zurich, Switzerland. Including 570 papers on theories and methods in the area of risk, safety and reliability, and their applications to a wide range of industrial, civil and social sectors, this book will be of interest to academics and professionals involved or interested in aspect of risk, safety and reliability in various engineering areas.

Safety, Reliability and Risk Analysis. Theory, Methods and Applications contains the papers presented at the joint ESREL (European Safety and Reliability) and SRA-Europe (Society for Risk Analysis Europe) Conference (Valencia, Spain, 22-25 September 2008). The book covers a wide range of topics, including: Accident and Incident Investigation; Crisi

The European Commission emphasizes, in its Fifth Research Framework, the “. . . emerging generic dependability requirements in the information society, stemming both from the ubiquity and volume of embedded and networked systems and services as well as from the global and complex nature of large scale information and communication infrastructures, from citizens, administrations and business in terms of technologies, tools, systems, applications and services". The series of Conference on Computer Safety, Reliability, and Security (Safecomp) contributes to satisfy these requirements by reviewing the state of the art, experiences, and new trends in the relevant scientific and industrial areas. Safecomp is intended to be a platform for technology transfer among academia, industry, and research institutions, providing the opportunity for exchange of ideas, opinions, and visions among experts. This year Safecomp celebrates the 20th anniversary, its first Conference having been organized in Stuttgart by EWICS (European Workshop on Industrial Computer Systems) in 1979, and we hope these Proceedings will contribute to the celebration by supporting Safecomp aims. The Proceedings include the 25 papers that have been presented orally at the Conference and the full version of the 14 papers that have been presented as posters, all of which were selected from 76 submissions. Papers almost uniformly take up Safecomp topics, dealing with the issues of Safety Assessment and Human Factors, Verification and Validation, Design for Safety, Formal Methods, and Security.

These proceedings present the results of the Eleventh International Conference on Dependability and Complex Systems DepCoS-RELCOMEX which took place in a picturesque Brunów Palace in Poland from 27th June to 1st July, 2016. DepCoS-RELCOMEX is a series of international conferences organized annually by Department of Computer Engineering of Wrocław University of Science and Technology since 2006. The roots of the series go as far back as to the seventies of the previous century – the first RELCOMEX conference took place in 1977 – and now its main aim is to promote a multi-disciplinary approach to dependability problems in theory and engineering practice of complex systems. Complex systems, nowadays most often computer-based and distributed, are built upon a variety of technical, information, software and human resources. The challenges in their design, analysis and maintenance not only originate from the involved technical and organizational structures but also from the complexity of the information processes that must be efficiently executed in a diverse, often hostile operational environment. Traditional methods of reliability evaluation focused only on technical resources are usually insufficient in this context and more innovative, multidisciplinary methods of dependability analysis must be applied. The diversity of the topics which need to be considered is well illustrated by the selection of the submissions in these proceedings with their subjects ranging from mathematical models and design methodologies through software engineering and data security issues up to practical problems in technical, e.g. transportation, systems.

Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.

This evidence-based book serves as a clinical manual as well as a reference guide for the diagnosis and management of common nutritional issues in relation to gastrointestinal disease. Chapters cover nutrition assessment; macro- and micronutrient absorption; malabsorption; food allergies; prebiotics and dietary fiber; probiotics and intestinal microflora; nutrition and GI cancer; nutritional management of reflux; nutrition in IBS and IBD; nutrition in acute and chronic pancreatitis; enteral nutrition; parenteral nutrition; medical and endoscopic therapy of obesity; surgical therapy of obesity; pharmacologic nutrition, and nutritional counseling.