Advances in magnetic resonance imaging (MRI) are transforming the investigation and treatment of cerebrovascular disease. Echoplanar techniques with diffusion and perfusion weighted imaging, together with developments in magnetic resonance spectroscopy and angiography, are replacing CT scanning as the diagnostic modality of choice. In this profusely illustrated book world leaders in these technologies review the scientific basis and clinical applications of MRI in stroke. It will appeal to a broad readership including stroke physicians, neurologists, neurosurgeons, rehabilitation specialists, and others with a clinical or research interest in cerebrovascular disease.

Stroke MRI is a new imaging tool providing detailed information of the pathophysiological aspects of cerebral ischemia. This book - with CD-ROM - includes a case collection of 25 hyperacute stroke patients, all imaged within six hours of stroke onset with a complete stroke MRI protocol. Stroke MRI and the established clinical methods are compared and recent results from single and multicenter trials are presented to demonstrate the advantages of MRI for stroke patients. The CD-ROM contains diffusion-, T2-, T2*-perfusion-weighted images and MR angiography. The CD and the book are complementary to avoid redundancy as far as possible.

Stroke is a condition that predominantly affects older people, often leading to death, disability and dependency as well as occupancy of hospital and nursing-home beds. Older stroke patients are similar in many ways to their younger counterparts, but at the same time exhibit several key differences. Their outcome and care are complicated by delayed diagnosis, polypharmacy, difficult rehabilitation, ageism, false assumptions of poor outcome, multiple co-morbidity, social issues including implications for independent living, ethical dilemmas, and many others. The proportion of older people is increasing every day and with it the burden of disease and disability. The implications this has for health services are immense, especially for long-term conditions. Despite this there is limited literature available to clinicians on stroke with a particular focus on this age group. Traversing the whole stroke pathway, Stroke in the Older Person brings together key discussions on every aspect of the disease as it affects the older person, including its general aspects and those very specific to the older populations. All chapters are written by highly experienced clinicians that offer up-to-date evidence-based information as well as practical tips to promote excellent, empathetic care to older patients. Over 30 chapters, this resource addresses the epidemiology, aetio-pathogenesis, clinical presentation, diagnostic work-up (including imaging), primary and secondary prevention, and rehabilitation of older people. There is a special focus on intracerebral haemorrhage, carotid re-vascularisation, transient ischaemic attack, cognitive impairment, research, ethical and moral dilemmas including DNAR, advanced directives and end-of-life care.

The care of stroke patients has changed dramatically. As well as improvements in the emergency care of the condition, there have been marked advances in our understanding, management and rehabilitation of residual deficits. This book is about the care of stroke patients, focusing on behavioural and cognitive problems. It provides a comprehensive review of the field covering the diagnostic value of these conditions, in the acute and later phases, their requirements in terms of treatment and management and the likelihood and significance of long-term disability. This book will appeal to all clinicians involved in the care of stroke patients, as well as to neuropsychologists, other rehabilitation therapists and research scientists investigating the underlying neuroscience.

This book is a unique source of practical information for frontline providers of care for stroke patients. It focuses on patient management—from stroke prevention through acute stroke management, through chronic care—and offers how-to guidance on implementing diagnostic and treatment protocols. Each chapter includes a bulleted list of key learning points; an evidence-based rationale for why the diagnostic and treatment recommendations work; a step-by-step approach to clinical application; practical recommendations from the authors; a critical pathway; and a bibliography. An entire chapter focuses on building a stroke team. Appendices include reproducible samples of order sets and a list of important medications.

Stroke is a user-friendly one-stop guide to the clinical management of stroke patients, from clinical and laboratory assessment to prognosis, rehabilitation, and stroke prevention. Written by leaders in stroke medicine, this book delivers concise, practice-oriented overviews and practical recommendations to guide decision-making. Stroke includes cutting-edge information on acute stroke treatment, primary stroke prevention, and the newest therapies for stroke-related symptoms and disorders. At once concise and authoritative, Stroke is the ideal reference for the clinician who wants to stay current with stroke diagnosis and therapy: ? Answers the questions that are frequently asked internists, neurologists in-training, medical students, stroke patients, caregivers, and the general population. ? Addresses both commonplace and rarer issues. ? Covers prevention of secondary stroke.

One in six suffers a stroke during their lifetime and stroke remains the major cause of new onset disability in adulthood. The worldwide burden of stroke is increasing due to an ageing population, however, globally haft of stroke victims are young. Stroke is the clinical diagnosis of an acute vascular incident and covers a multitude of pathophysiological causes. The clinician needs imaging to make decisions on acute treatment as well as to plan a secondary prevention strategy: a non-contrast CT and a Duplex of the carotids followed by an aspirin as a one size fits all strategy does not always provide sufficient support for those decisions. Presently, fast, generally available, and non-invasive imaging provides new possibilities of establishing a cause of stroke, provide specific information on the brain parenchyma – including possibly salvageable tissue and micro-bleeds – as well as allowing for more specific prognostication in acute stroke. This eBook covers both ischemic and haemorrhagic stroke and includes hot topics such as micro-bleeds, salvageable tissue and spot-sign, clinically challenging issues including movement artefacts in MRI as well as an overview of present options including pragmatic and feasible suggestions for an approach to state of the art acute imaging.

Stroke represents a clinical syndrome of rapid onset of focal or sometimes global cerebral deficit with a vascular cause, lasting more than 24 hours or leading to death. Eighty per cent of all strokes are ischaemic, 15% are due to intracerebral haemorrhage, and 5% to subarachnoid haemorrhage. Correct diagnosis is important because treatment options for ischemic stroke may be contraindicated in case of intracerebral haemorrhage. Such exact diagnosis requires state-of-the-art imaging of the brain. But which kind of imaging, how quickly should it be done, should this include imaging of cerebral blood flow, and what is the most cost effective approach? Answering these questions may help to further narrow the gap between experimental and clinical research as well may substantially improve the patient's care.

Thrombolytic therapy for stroke with the introduction of tissue plasminogen activator (t-PA) was a boon to stroke physicians, since it meant that morbidity and mortality could be reduced with the optimal use of t-PA. The editor and his well-respected contributors offer the reader their personal perspectives on the evidence-based use of various thrombolytic and anti-thrombotic agents that are available and that can provide successful outcomes. Thrombolytic and Antithrombotic Therapy for Stroke is updated and thoroughly referenced. Everyone working in the casualty/emergency room must read this clearly-written text.

Acute Stroke Management in the First 24 hours bridges the clinical application gap by offering a practice-based approach to treating ischemic and hemorrhagic stroke. The comprehensive text, written by international experts in the field of stroke care, covers all aspects of stroke care, including review of stroke systems, clinic features, neuroimaging diagnostic characteristics, and pre-hospital care and challenges. Practical clinical studies in each chapter engage readers in the discussion of common diagnostic pitfalls and work challenges. Chapters also include detailed figures and management algorithms, making this book an easy-to-use reference guide ideal for first responders and clinicians working in emergency medicine, neurology, neurosurgery, and critical care.