This book deals with central concepts in population genetics, describing the main evolutionary processes that influence the allele frequency distribution and change. The different chapters discuss topics such as population size and structure, migration, inbreeding and interbreeding, mechanisms of extinction and speciation, along with different data techniques and molecular methods used for detecting DNA sequence variation in the study of genetic polymorphisms. Part of the book includes statistical and computational methods commonly used to process population genetics data, which constitute an essential tool for understanding the concepts discussed. The book will be a useful reference for graduate students and researchers working on population genetics, and other related areas including microbiology, genetics, molecular biology, ecology, anthropology and others.

Recently, technological progress and the rise of DNA barcoding efforts have led to a significant increase in the availability of molecular datasets on intraspecific variability. Carcinologists and other organismal biologists, who want to use molecular tools to investigate patterns on the scale of populations, face a bewildering variety of genetic m

This book introduces readers to classical population genetics and the ways in which it can be applied to practical problems, including testing for natural selection, genetic drift, genetic differentiation, population structuring, gene flow and linkage disequilibrium. It provides a comprehensive monograph on the topic, addressing the theory, applications and evolutionary deductions, which are clearly explained using experimental results. It also offers separate chapters on origin, establishment and spread of chromosomal aberrations in populations along with details of culturing, maintaining and using Drosophila ananassae (genetically unique and the most commonly used species along with D. melanogaster) for genetic research. Encompassing topics like genetics, evolution, Drosophila genetics, population genetics, population structuring, natural selection and genetic drift in considerable detail, it provides a valuable resource to undergraduate and postgraduate students, as well as researchers at all level. This book explores some fundamental questions concerning the role of natural selection and genetic drift on the degree of inversion polymorphism. India, with its wide diversity in geo-climatic conditions, provides an excellent platform to conduct such studies. The book showcases sampling records of inversion frequencies in natural Indian populations of D. ananassae that cover more than two decades. It highlights case studies in which sampling data on inversion frequencies was combined with that from earlier surveys, generating a time series that allows the evolutionary dynamics of inversion polymorphism to be explored. Such long time series are rare but nonetheless crucial for studying the evolutionary dynamics of inversion polymorphism. The population-genetic analysis discussed is unprecedented in terms of its temporal (two decades) and spatial (most regions of India covered) scale and investigates the patterns of polymorphic system in D. ananassae to see if there is any temporal divergence. It endeavors to present a holistic picture of inversion polymorphism across the country (India). Chromosomal aberrations, particularly paracentric inversions, are used as a tool for discussing population genetic studies, helping human geneticists, gynecologists and other medical professionals understand why some aberrations are fatal in humans, with affected embryos often not surviving the first trimester of pregnancy, while similar aberrations in Drosophila flies aid in their adaptation to the environmental heterogeneity across the globe.

This book explores how human population genetics has emerged as a means of imagining and enacting belonging in contemporary society. Venla Oikkonen approaches population genetics as an evolving set of technological, material, narrative and affective practices, arguing that these practices are engaged in multiple forms of belonging that are often mutually contradictory. Considering scientific, popular and fictional texts, with several carefully selected case studies spanning three decades, the author traces shifts in the affective, material and gendered preconditions of population genetic visions of belonging. Topics encompass the debate about Mitochondrial Eve, ancient human DNA, temporality and nostalgia, commercial genetic ancestry tests, and tensions between continental and national genetic inheritance. The book will be of particular interest to scholars and students of science and technology studies, cultural studies, sociology, and gender studies.

Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. - Comprehensively explains the use of population genetics and genomics in medical applications and research - Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals - Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now

Now updated for its second edition, Population Genetics is the classic, accessible introduction to the concepts of population genetics. Combining traditional conceptual approaches with classical hypotheses and debates, the book equips students to understand a wide array of empirical studies that are based on the first principles of population genetics. Featuring a highly accessible introduction to coalescent theory, as well as covering the major conceptual advances in population genetics of the last two decades, the second edition now also includes end of chapter problem sets and revised coverage of recombination in the coalescent model, metapopulation extinction and recolonization, and the fixation index.

Population genetics is the basis of evolutionary studies, and has been widely used in several researches. This recent field of science has important applications for the management of populations (natural and domesticated), as well as for evolutionary studies of the various factors that affect gene frequencies over time and spatial distribution.In this work, presented in three sections (Population and Quantitative Genetics, Genetic Diversity in Crop Management, Population Genetics for Conservation Studies), the reader will find cutting-edge information in carefully selected and revised works.This book is intended for all researchers, academics, and students who are interested in the intriguing area of population genetics.