After her diagnosis of hormone-negative breast cancer, health journalist Patricia Prijatel did what any reporter would do: start investigating the disease, how it occurs, how it's treated, and how to keep it from recurring. While she learned that important research on triple-negative breast cancer (TNBC) was emerging, she found a noticeable lack of resources on the disease, which differs from hormone-positive breast cancer in important ways, including prognosis and treatment options. Triple-negative breast cancer disproportionately affects younger women and African-American women-and some forms of it can be more dangerous than other types of breast cancer. But there are many reasons to be hopeful, as Prijatel shows in this book. Surviving Triple-Negative Breast Cancer delivers research-based information on the biology of TNBC; the role of genetics, family history, and race; how to navigate treatment options; understanding a pathology report; and a plethora of strategies to reduce the risk of recurrence, including diet and lifestyle changes. In clear, approachable language, Prijatel provides a fact-filled guide based on a vast array of scientific studies. Woven throughout the book are stories of women who have faced TNBC. These are mothers, wives, daughters, and sisters who went through a variety of medical treatments and then got on with life--one competes in triathlons, two had babies after being treated with chemo, one got remarried in her 50s, and one just celebrated the 30th birthday of the son she was nursing when she was diagnosed. Writing with honesty and humor, Prijatel delivers an inspiring message--that TNBC is a disease to take seriously, with proper and occasionally aggressive treatment, but it is not automatically a killer. Most women diagnosed with the disease survive and go on to live full lives. Surviving Triple-Negative Breast Cancer is a roadmap for women who want to be empowered through their treatment and recovery.

Triple negative breast cancers (TNBC) are a biologically aggressiveform of breast cancer and constitute approximately 10-15% of all breast cancerpatients. Distant metastasis, lack of clinically targeted therapies andprognostic markers, makes the disease difficult to treat. Till now not muchwork has been carried out on this deadly disease. This book provides an overview of TNBC etiology, its treatmentstrategies and prognostic markers to identify the outcome of standard therapies.Signalling pathways namely cell proliferation, angiogenesis, invasion andmetastasis, apoptosis, autophagy and others involved in complicating thedisease have been described in the chapters to convey an understanding aboutthe disease mechanisms. All the possible drugs either in pre-clinical orclinical stages have also been mentioned with data that depicts their efficiencyin targeting altered genes. The book also introduces the reader to herbalmedicine exhibiting high potency to target TNBC, their synthetic analogs usedduring chemotherapy and their ability to fight against chemoresistance. Theconcept of phytonanotechnology has also been discussed. The book helps createawareness among a broad range of readers about TNBC. It points to prioritizingthe upgradation of health care facilities and re-designing future treatmentstrategies to provide maximum benefit to breast cancer patients.

Written by experts in psycho-oncology, this book synthesizes the findings of the latest research on women's cancers to empower women to make informed choices about treatment options. Each year, hundreds of thousands of women are diagnosed with cancer in the United States alone. The total number affected is larger still, comprising siblings, parents, partners, and children of these women. In this single-volume work, an international team of experts address the physical, medical, and psychological matters that are triggered by a diagnosis of having a form of "women's cancer"—breast, cervical, endometrial, gestational, ovarian, uterine, vaginal, and vulvar being some of the more common. The handbook examines and explains each type of women's cancer, covering the specifics of incidence, diagnosis, treatment options, and more, providing an up-to-date guide for women and their families to assist in making informed choices about their treatment options. The book includes personal accounts from women who survived cancers and beat their emotional challenges, addresses myths versus realities regarding women's cancers, and covers relevant, related topics such as race, sexual orientation, religion, and cancer coping. Special attention is given to the impact of women's cancers on relationships, intimacy, and body image, as well as psychological factors such as anxiety, depression, and fear.

The most popular annual guide of its kind—fully revised and updated to reflect all new clinical developments in every field of medicine For 60+ years, CURRENT Medical Diagnosis and Treatment―the flagship volume of the renowned Lange medical series―has been delivering the authoritative information students, residents, and clinicians need to build their medical knowledge, expertise, and confidence. Written by top experts in their fields, this unmatched guide is formatted in a way that enables you to find the answers you need quickly and easily. CURRENT Medical Diagnosis and Treatment 2022 focuses completely on solving practical bedside clinical issues without spending too much time on pathophysiology. It includes full review of all primary care topics, including gynecology, obstetrics, dermatology, ophthalmology, otolaryngology, psychiatry, neurology, toxicology, and urology. You’ll find everything you need to know about inpatient and outpatient care, along the with the most relevant diagnostic tools for day-to-day practice. Features: 320 images Hundreds of quick-access drug treatment tables, with indexed tradenames and updated drug prices Includes an annual review of advances in HIV treatment Includes Essentials of Diagnosis for most diseases/disorders Diagnostic/treatment algorithms present critical information in an at-a-glance format Up-to-date references provide peer-reviewed, evidence-based information "Electronic only" chapters available to all book customers, not just to CMDT online subscribers Expanded chapter content available online and in ebook for all chapter content

The #1 annually updated general medical text—presents the most important diagnostic and treatment recommendations as well as the most useful new clinical developments in every field of adult medicine. For more than six decades, CURRENT Medical Diagnosis & Treatment has been delivering the authoritative information students, residents, and clinicians need to build their medical knowledge, expertise, and confidence. Written by top experts in their fields, this unmatched guide is formatted in a way that enables readers to find the answers they need quickly and easily. CURRENT Medical Diagnosis & Treatment 2024 reflects the latest developments in medicine, guidelines, references, and more. You’ll find authoritative, evidence-based coverage of more than 1,000 diseases and disorders along with a concise, yet thorough synopsis of diagnosis and treatment. This trusted classic covers all aspects of outpatient and inpatient care and includes discussion of new developments and breakthroughs in medicine. CURRENT Medical Diagnosis & Treatment 2024 features: A comprehensive approach to patient care, focusing on the diagnostic tools relevant to daily practice Coverage of more than 1,000 diseases and disorders Hundreds of drug treatment tables for quick access to indexed trade names Annual updates to topics in all chapters in a consistent format, drugs, tables, and images Year in Review highlighting the many topics with significant clinical changes over the last year Essentials of Diagnosis for most diseases/disorders Diagnostic and treatment algorithms present complex information in an at-a-glance style Hundreds of full-color photos and illustrations New to this edition: Latest USPSFT recommendations for cardiovascular risk prevention Significant new opioid prescribing guidelines from the CDC Clarification on the distinction between uncontrolled hypertensive and hypertension emergency Latest classification of lymphomas released by the WHO Recommendations for the initiation and titration of treatment for chronic hypertension in pregnancy Current treatment guidelines and medications for H pylori infection Classification of the role, dosing, and potential risks of JAK inhibitors and anti-23 antibody (Risankizumab) in the treatment of IBD Updates that underscore the growing utility of combination treatments for high LDL levels, especially among high and very high-risk patients The WHO revision of the pathological classification of renal cell carcinoma to assist with prognosis prediction and treatment decisions

The 50th Anniversary Edition of the World’s Most Popular Annual General Medicine Book – Celebrated with a New Full-Color Design Includes 5 online-only chapters at no additional cost at www.AccessMedicine.com/CMDT Your first place to turn for current developments that promise better patient care Written by clinicians renowned in their respective fields, CMDT offers the most current insight into symptoms, signs, epidemiology, and treatment for more than 1,000 diseases and disorders. For each topic you’ll find concise, evidence-based answers to questions regarding both hospital and ambulatory medicine. This streamlined clinical companion is the fastest and easiest way to keep abreast of the latest medical advances, prevention strategies, cost-effective treatments, and more. MORE usable patient-care information in LESS text: A strong focus on the clinical diagnosis and patient management tools essential to daily practice Full review of all internal medicine and primary care topics, including gynecology and obstetrics, dermatology, neurology, and ophthalmology The only text with an annual review of advances in HIV treatment Hundreds of drug treatment tables, with indexed trade names and updated prices – plus helpful diagnostic and treatment algorithms Recent references with PMID numbers for fast access to abstracts or full-text articles ICD-9 codes listed on the inside covers Five online-only chapters available at no additional cost at www.AccessMedicine.com/CMDT NEW to this edition: Full-color photos and illustrations integrated with text throughout book, including much expanded dermatology and ophthalmology images Newly introduced topics: E. coli O145, floppy iris syndrome, and expanded coverage of H1N1 influenza A New information: emerging role for B-type natriuretic peptide (BNP) as marker of early left ventricular myocardial failure, new approaches to correction of aortic stenosis and to aortic regurgitation in Marfan syndrome, risks of typical and atypical antipsychotic medications, and new hypoglycemic agents Substantial update on cardiology and hypertension, including use of stents and cardiac resynchronization therapy with biventricular pacemaker insertion, recent ACC/AHA criteria for appropriateness of coronary revascularization, use of prasugrel and clopidogrel compared with aspirin in prevention of stent thrombosis, dronedarone and catheter ablation for atrial fibrillation and dabigatran versus warfarin in prevention of atrial fibrillation-related stroke, as well as guidelines for developing an antihypertensive regimen Updated information on pathogenesis and treatment of immune and drug-induced thrombocytopenia, new investigational anticoagulants such as rivaroxaban and idraparinux, risk stratification and prophylactic regimens for deep venous thrombosis and venous thromboembolism, and a prognostic model for pulmonary emboli Expanded information on methicillin-resistant Staphylococcus aureus, treatment of pharyngitis and laryngitis, approaches to the diagnosis of syphilis, diagnosis and complications with borreliosis and its coinfections, acute and chronic viral hepatitides, amyloidosis, treatment and prognosis of venous stasis ulcers, and therapy for heat stroke and burns Substantially updated treatment sections: HIV infections and AIDS and advances in therapy for breast cancer in women Updated section on immunization requirements New CMDT Online chapter on Sports Medicine and Outpatient Orthopedics