This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson's disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system. - Offers a unique emphasis on the neurological manifestations of diabetes - Provides thorough coverage of the clinical, experimental, mechanistic, therapeutic, peripheral, and central aspects of diabetic neuropathy - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

The thoroughly revised and updated Third Edition of the acclaimed Modern Epidemiology reflects both the conceptual development of this evolving science and the increasingly focal role that epidemiology plays in dealing with public health and medical problems. Coauthored by three leading epidemiologists, with sixteen additional contributors, this Third Edition is the most comprehensive and cohesive text on the principles and methods of epidemiologic research. The book covers a broad range of concepts and methods, such as basic measures of disease frequency and associations, study design, field methods, threats to validity, and assessing precision. It also covers advanced topics in data analysis such as Bayesian analysis, bias analysis, and hierarchical regression. Chapters examine specific areas of research such as disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, and clinical epidemiology.

World Clinics: Diabetology - Complications of Diabetes, Volume 2, Number 1 is the latest issue in the World Clinics Diabetology series, covering recent advances in the understanding of aetiopathogenesis, evaluation, and management of diabetic complications. This issue is divided into fourteen articles, covering a wide range of topics including diabetes and tuberculosis, diabetic retinopathy, kidney disease, sexual dysfunction, diabetic foot, coronary artery disease, and hypoglycaemia. The final article on diabetic foot provides information on assessment and classification on this particular complication of the disease. World Clinics: Diabetology - Complications of Diabetes, Volume 2, Number 1 is enhanced by 110 images and illustrations, and each article is followed by a comment from the editors making this an authoritative and up-to-date review of these areas of diabetology. Key Points Latest issue in the World Clinics Diabetology series Series also includes Type 2 Diabetes Mellitus (9789351520016) Fourteen articles on current important topics in diabetology Each article is followed by comment from the editors, highlighting important issues 110 images and illustrations

"Overall, the book walks a delicate balance between evidence and advocacy regarding the care of people with chronic conditions. Nolte and McKee conclude the volume with the following: 'A first step is to recognize that something must be done. A second, which we hope will be facilitated by the evidence provided in this book, is to realize that something actually can be done, and that they can do it (p. 240)'. The overarching desire to match the need for evidence with the reality that advocates (including policy-makers) need a reasoned voice makes the book well suited to health policy deliberations." International Journal of Integrated Care The complex nature of many chronic diseases, which affect people many different ways, requires a multifaceted response that will meet the needs of the individual patient. Yet while everyone agrees that the traditional relationship between an individual patient and a single doctor is inappropriate, there is much less agreement about what should replace it. Many countries are now experimenting with new approaches to delivering care in ways that do meet the complex needs of people with chronic disorders, redesigning delivery systems to coordinate activities across the continuum of care. Yet while integration and coordination have an intuitive appeal, policy makers have had little to help them decide how to move forward. The book systematically examines some of the key issues involved in the care of those with chronic diseases. It synthesises the evidence on what we know works (or does not) in different circumstances. From an international perspective, it addresses the prerequisites for effective policies and management of chronic disease. Taking a whole systems approach, the book: Describes the burden of chronic disease in Europe Explores the economic case for investing in chronic disease management Examines key challenges posed by the growing complexity in healthcare including prevention, the role of self-management, the healthcare workforce, and decision-support Examines systems for financing chronic care Analyses the prerequisites for effective policies for chronic care Caring for People with Chronic Conditions is key reading for health policy makers and health care professionals, as well as postgraduate students studying health policy, health services research, health economics, public policy and management. Contributors: Reinhard Busse, Elisabeth Chan, Anna Dixon, Carl-Ardy Dubois, Isabelle Durand-Zaleski, Daragh K Fahey, Nicholas Glasgow, Monique Hejmans, Izzat Jiwani, Martyn Jones, Cécile Knai, Nicholas Mays, Martin McKee, Ellen Nolte, Thomas E Novotny, Joceline Pomerleau, Mieke Rijken, Dhigna Rubiano, Debbie Singh, Marc Suhrcke.

The Handbook of Applied System Science is organized around both methodological approaches in systems science, and the substantive topic to which these approaches have been applied. The volume begins with an essay that introduces three system science methods: agent-based modeling, system dynamics, and network analysis. The remainder of the volume is organized around three broad topics: (1) health and human development, (2) environment and sustainability, and (3) communities and social change. Each part begins with a brief introductory essay, and includes nine chapters that demonstrate the application of system science methods to address research questions in these areas. This handbook will be useful for work in Public Health, Sociology, Criminal Justice, Social Work, Political Science, Environmental Studies, Urban Studies, and Psychology. Chapter 14 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license available at http://www.taylorfrancis.com/books/e/9781315748771.

Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Endocrine System Diseases. The editors have built Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Endocrine System Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sources: the surge of scientific advances contrast with an unprecedented amount of human suffering. Thus, a patient centered and an evidence based approach with the capacity to produce measurable clinical and economic outcomes is required. The purpose of this textbook is multiple: to offer a comprehensive resource covering all aspects of outpatient management; to address diabetes as a health problem from an epidemiological, economic and clinical perspective; to discuss the role of social determinants of health on the worldwide increase in diabetes; to highlight the challenges and obstacles in providing adequate care; and to outline a multidisciplinary approach to management in which medical visits retain their importance as part of a team comprising the patient, his or her family and a multidisciplinary group of health professionals who are able to move beyond the traditional approach of diabetes as a disease and greatly improve outcomes.