Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. - Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases - Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases - Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems

Advanced Drug Delivery Systems for Colonic Disorders present the current state of the art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters are written in a way that allows the audience to not only become familiar with the most recent advancement in the field, but to better understand them by referring to various illustrations, figures, and informative tables. The contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the current status of clinical trials in the area. Advanced Drug Delivery Systems for Colonic Disorders is the perfect resources for researchers in pharma, biomaterials, and nutrition to familiarize themselves with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications. - Covers recent perspectives and challenges towards the treatment of colonic disorders - Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of colonic disorders - Discusses drug delivery strategies to manage inflammatory bowel disease (chronic inflammation in the digestive tract), ulcerative colitis (inflammation and ulcers in colon), Crohn's disease, Colonic polyps, Shigellosis, Colon Bleeding or Hemorrhage, Diverticulosis and colon cancer

Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics. Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases. - Offers comprehensive coverage of drug delivery to treat metabolic diseases - Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of metabolic disorders - Includes the most recent research on diagnostic methods and treatment strategies using controlled drug delivery systems

This new volume covers recent trends of NDDS in the management of the most frequently occurring chronic diseases. The authors outline the different materials that can help prepare NDDS with desired properties. The book looks at NDDS applications for central nervous system (CNS) diseases, including Alzheimer’s and Parkinson’s as well as for HIV, cancer diabetes, asthma and respiratory complications, and diabetic retinopathy. Chapters also look at the use of NDDS in herbal drug delivery, the involvement of artificial intelligence in development of NDDS, and more. This new volume provides an informative overview of the current scope of NDDS for chronic diseases as well as its future development, including how artificial intelligence can be used in novel formulations. The book will prove useful for research scholars and researchers.

Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation. - Identifies recent developments and current trends in anti-inflammation therapy - Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products - Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies - Contains a blend of editors from both academia and industry

Advanced and Modern Approaches for Drug Delivery explores novel approaches currently used for drug delivery, including the must up-to-date techniques and technology. The approaches discussed allow pharmaceutical scientists to design effective drug delivery systems or devices for the management and treatment of numerous diseases and conditions. Detailed information on a wide variety of subjects, including dendrimers, lipid nanostructures, solid lipid nanoparticles, stimuli-responsive smart systems, self-assembled protein-drug nanoparticles, nanoconjugate formulations, nanofibers, iontophoretic systems, microneedle systems, ultra-sound triggered systems, targeted carrier-based intracellular delivery systems, resealed erythrocyte-based systems, 3 D-printing tool, site-specific monoclonal antibodies, and bio-inspired systems are all comprehensively discussed. With contributions from those in academia and industry, this book is an excellent reference for all those needing to understand drug delivery systems. - Provides thorough insights into the most up-to-date approaches and technologies for drug delivery and therapeutics - Discusses possible future approaches - Includes perspectives from industry and academia

Nanotechnology can treat diseases by site-specific and target-oriented delivery of precise medicines. Nanomaterials improve the efficacy of drugs and selective diagnosis. The book covers detection and treatment. It explains the use of nanocarriers for a variety of diseases such as cardiovascular and respiratory diseases, cancer, and ulcerative colitis. It includes topical, transdermal, and ocular drug delivery and combined medication delivery.

This book presents an overview of the rapidly developing field of nanotechnology applications in drug delivery systems and covers a variety of technologies and materials that help in achieving vast variation in the particle size needed in technology and drug delivery-based research. It discusses nanotechnology’s use in healthcare for the development of target-specific drug therapy and smart field systems and in the pharmaceutical industry to improve the quality, efficacy, and shelf life of medicines. Bringing together principles, theory, practice, and applications of nanotechnology, the book is a useful resource for chemists, physicists, biomedical researchers, engineers, advanced undergraduate and graduate-level students in nanotechnology, researchers in pharmaceutical sciences, chemistry, biology, biotechnology engineering, and general readers in nanotechnology.