Intended for students of intermediate organic chemistry, this text shows how to write a reasonable mechanism for an organic chemical transformation. The discussion is organized by types of mechanisms and the conditions under which the reaction is executed, rather than by the overall reaction as is the case in most textbooks. Each chapter discusses common mechanistic pathways and suggests practical tips for drawing them. Worked problems are included in the discussion of each mechanism, and "common error alerts" are scattered throughout the text to warn readers about pitfalls and misconceptions that bedevil students. Each chapter is capped by a large problem set.

This book shows readers how to draw reasonable mechanisms for reactions they have never seen before. This skill will help readers develop a good command of electron-pushing before tackling the detailed mechanistic analysis of physical organic chemistry. It is organized according to mechanistic types in order to clarify the basic mechanistic similarities among apparently diverse reactions. One of the unique features of this book is the common error alert, which warns about common pitfalls and misconceptions.

Every Aspiring Organic Chamist Must Learn How To Write Reasonable Mechanisms For Organic Reactions, Yet Few Text Books Are Devoted To Teaching Them How To Do It. This Text Will Help Students And Researchers In Organic Chemistry And Allied Fields To Develop This Indispensable Still.

The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures. The volume "Reactions Involving a Carbonyl Compound as Electrophilic Component" covers the following topics: Biginelli Reaction Strecker Reaction Hantzsch Pyridine Synthesis Mannich Reaction Petasis Reaction Willgerodt-Kindler Reaction Kabachnik-Fields Reaction Passerini Reaction Ugi Reaction Gewald Reaction

This comprehensive laboratory text provides a thorough introduction to all of the significant operations used in the organic lab and includes a large selection of traditional-scale and microscale experiments and minilabs. Its unique problem-solving approach encourages students to think in the laboratory by solving a scientific problem in the process of carrying out each experiment. The Second Edition contains a new introductory section, "Chemistry and the Environment," which includes a discussion of the principles of green chemistry. Several green experiments have been added, and some experiments from the previous editions have been revised to make them greener.

Preface To the Instructor Acknowledgments Introduction Problem Solving in the Organic Chemistry Laboratory Scientific Methodology Organization of This Book A Guide to Success in the Organic Chemistry Lab Laboratory Safety Safety Standards Protecting Yourself Preventing Laboratory Accidents Reacting to Accidents: First Aid Reacting to Accidents: Fire Chemical Hazards Finding and Using Chemical Safety Information Chemistry and the Environment Disposal of Hazardous Wastes Green Chemistry Part I Mastering the Operations 1 The Effect of pH on a Food Preservative 2 Separating the Components of ldquo;Panacetinrdquo; 3 Identifying a Constituent of ldquo;Panacetinrdquo; 4 Synthesis of Salicylic Acid from Wintergreen Oil 5 Preparation of Synthetic Banana Oil 6 Separation of Petroleum Hydrocarbons 7 A Green Synthesis of Camphor 8 Identification of a Petroleum Hydrocarbon 9 Isolation and Isomerization of Lycopene from Tomato Paste 10 Isolation and Identification of the Major Constituent of Clove Oil 11 Identification of Unknown Ketones 12 The Optical Activity of -Pinene: A Chemical Mystery Part II Correlated Laboratory Experiments 13 Investigation of a Chemical Bond by Infrared Spectrometry 14 Properties of Common Functional Groups 15 Thin-Layer Chromatographic Analysis of Drug Components 16 Separation of an Alkane Clathrate 17 Isomers and Isomerization Reactions 18 Structures and Properties of Stereoisomers 19 Bridgehead Reactivity in an S N 1 Solvolysis Reaction 20 Reaction of Iodoethane with Sodium Saccharin, an Ambident Nucleophile 21 Dehydration of Methylcyclohexanols and the Evelyn Effect 22 Testing Markovnikovrsquo;s Rule 23 Stereochemistry of Bromine Addition totrans-Cinnamic Acid 24 A Green Synthesis of Adipic Acid 25 Preparation of Bromotriphenylmethane and the Trityl Free Radical 26 Chain-Growth Polymerization of Styrene and Methyl Methacrylate 27 Synthesis of Ethanol by Fermentation 28 Reaction of Butanols with Hydrobromic Acid 29 Borohydride Reduction of Vanillin to Vanillyl Alcohol 30 Synthesis of Triphenylmethanol and the TritylCarbocation 31 An Unexpected Reaction of 2,3-Dimethyl-2,3-butanediol 32 Identification.