In consultation with Dr. Charles Lightdale, Dr. DiMaio has assembled a list of articles devoted to endoscopy in hepatology with the most current and clinically relevant content. Dr. DiMaio invited top experts from well-known institutions to contribute reviews on the following topics: EUS in the evaluation of unexplained biliary dilation and liver function test abnormalities; EUS-guided liver biopsy; Advances in endoscopic imaging of the biliary tree; Expert evaluation of indeterminate biliary strictures; Stenting for benign and malignant biliary strictures; Endoscopic management of biliary issues in the liver transplant patient; Endoscopic management of complex biliary stone disease; EUS-guided biliary drainage; ERCP and EUS-guided drainage of the gallbladder; EUS-guided interventions for the measurement and treatment of portal hypertension; Endoscopic management of portal hypertension-related bleeding; EUS for diagnosis and staging of liver tumors; ERCP-guided ablation for cholangiocarcinoma; and EUS-guided ablation of liver tumors. Readers will come away with the most current clinical information they need to improve outcomes in patients with liver disease.

Together with Consulting Editor Dr. Charles Lightdale, Dr. Qiang Cai has put together a comprehensive issue devoted to gastroparesis. Expert authors have contributed clinical review articles on the following topics: Epidemiology and Pathophysiology of Gastroparesis; Non-Diabetic Gastroparesis; Clinical Manifestations and Natural History of Patients with Gastroparesis; Evaluation of Patients with Suspected Gastroparesis; Symptomatic Management of Gastroparesis; Gastric Electrical Stimulator for treatment of Gastroparesis; Surgical Treatment for Gastroparesis; Botulinum Toxin Injection for Treatment of Gastroparesis; Stent Placement for Treatment for Gastroparesis; Technical Aspects of Per Oral Endoscopic Pyloromyotomy; Gastric Emptying Scintigraphy for Evaluation of Patients with Gastroparesis before Per Oral Endoscopic Myotomy; Outcomes of Per Oral Endoscopic Pyrolomyotomy in France; Outcomes of Per Oral Endoscopic Pyloromyotomy in China; Outcomes of Per Oral Endoscopic Pyloromyotomy in the United States.. Readers will come away with the information they need to improve endoscopic techniques and improve patient outcomes.

Optimizing Endoscopic Operations, An Issue of Gastrointestinal Endoscopy Clinics

As Executive Director of the H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine, Dr. Chang brings the wealth of hix experience and knowledge to the topic of interventional endoscopic ultrasound. His issue is divided into two sections, the first dealing with the best practices of interventional EUS. Articles in this section address FNA of solid pancreatic tumors, pancreatic cysts, diagnosis of SMT's, lung cancer staging, pancreatic drainage, and celiac neurolysis. The second section addresses emerging technologies for intervention EUS. These articles discuss pancreatic cyst ablation, vascular access and therapy, anti-tumor agents, fiducial markers and brachytherapy, image enhancement, tumor ablation, and anastomosis.

Dr. Gress has assembled top experts to discuss the latest advances of using endoscopic ultrasound for diagnostic and therapeutic purposes. The issue has review articles devoted to the following topics: EUS Elastography; Contrast-Enhanced EUS; New developments in EUS- FNA Tissue Acquisition; EUS FNA: Cytologic and histologic using new techniques for interpretation; New EUS Techniques for diagnosing pancreatic neoplasms; EUS for diagnosing and treating pancreatic cysts; The role of EUS in the diagnosis of Autoimmune Pancreatitis; Therapeutic EUS for cancer treatment; and EUS-guided techniques in biliary drainage, pancreatic drainage, necrosectomy, pelvic fluid collections, hemostasis techniques, and gastrojejunostomy. The issue ends with articles that look at training issues and the future of EUS. Readers should leave with the clinical information they need to embrace the latest advances of endoscopic ultrasonography.

In this issue of Gastrointestinal Endoscopy Clinics of North America, we invited pioneers and experts in this field to share recent advancements and expansions of ESD and its technical aspects in different organ systems. In addition, this issue covers the associated techniques of per oral endoscopic myotomy (POEM) and natural orifice transluminal endoscopic surgery (NOTES) to further advance understanding of the latest breakthroughs in endoscopic therapy. Current trends surrounding ESD around the world—in Asia, Europe, and the United States—are addressed as well. Some articles include videos for readers to watch ESD procedures in action, performed by experts, for easier understanding of ESD techniques. The Guest Editors expect that this issue will inspire more physicians to explore the expanding possibilities of endoscopic therapy such as ESD and POEM and to advocate minimally invasive treatment for patients.

In this issue of Gastrointestinal Endoscopy Clinics of North America, guest editor Dr. Amrita Sethi brings her considerable expertise to the topic of Submucosal and Third Space Endoscopy. Endoscopic submucosal dissection (ESD) is now recognized as one of the preferred treatment modalities for premalignant gastrointestinal epithelial lesions and early gastric cancer without lymph node metastasis. ESD techniques require advanced skills, and this issue brings together top experts in the field who provide the information endoscopists need to improve these skills. - Contains 15 practice-oriented topics including building the toolbox of devices to optimize a practice in submucosal endoscopy; understanding the principles of electrocautery for submucosal endoscopy; endoscopic submucosal dissection in the colon and rectum; techniques for peroral endoscopic myotomy, from mouth to anus; management of adverse events of submucosal endoscopy; and more. - Provides in-depth clinical reviews on submucosal and third space endoscopy, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Dr. Gralnek is considered an authority on GI bleeding, and he has invited experts in their respective fields to contribute to this issue. The content is divided up between Acute Non-Variceal Upper GI Hemorrhage and Acute Lower Gastrointestinal Hemorrhage. Articles are devoted to the follow topics: Initial assessment, risk stratification and early management; Endotherapy of peptic ulcer bleeding; Endoscopic hemostasis of non-variceal, non-ulcer UGIH; Emerging endoscopic treatments for NVUGIH; The cutting edge: doppler ultrasound in guiding endoscopic hemostasis; The role of interventional radiology in NVUGIH; Managing antithrombotic agents in the setting of acute GI bleeding; Patient presentation, risk stratification and initial management; Colonoscopy: Diagnosis, timing and bowel preparation; The role of endoscopic hemostasis therapy; and Prevention of recurrent lower GI hemorrhage. Readers will come away with the most current clinical infomration on how to manage and prevent GI bleeding.

In consultation with Dr. Charles Lightdale, Dr. Cai has assembled a list of articles devoted to gastroparesis with the most current and clinically relevant content. Dr. Cai invited top experts from well-known institutions to contribute reviews on the following topics: Epidemiology and Pathophysiology of Gastroparesis; Diabetic Gastroparesis and Non-Diabetic Gastroparesis; Clinical Manifestations and Natural History of Patients with Gastroparesis; Evaluation of Patients with Suspected Gastroparesis; Symptomatic Management of Gastroparesis; Gastric Electrical Stimulator for Treatment of Gastroparesis; Surgical Treatment for Gastroparesis; Botulinum Toxin Injection for Treatment of Gastroparesis; Stent Placement for Treatment for Gastroparesis; Technical Aspects of Per Oral Endoscopic Pyloromyotomy; Gastric Emptying Scintigraphy for Evaluation of Patients with Gastroparesis before Per Oral Endoscopic Myotomy; Outcomes of Per Oral Endoscopic Pyrolomyotomy in France; Outcomes of Per Oral Endoscopic Pyloromyotomy in China; and Outcomes of Per Oral Endoscopic Pyloromyotomy in the United States. Readers will come away with the most current clinical information they need to inform clinical decisions to improve patient outcomes.

The topics covered in this issue, an update from what was first published in the Gastrointestinal Endoscopy Clinics in 2008, reflect the fact that NOTES is seeing a resurgence in popularity. Now, eight years later, there is more data to confirm safety, to look at the best options for using natural orifices, and to talk about optimal training scenarios. The Guest Editor has enlisted some of the top experts on NOTES to contribute articles devoted to Seminal Developments: SM Tunnel Technique; Peroral Endoscopic Myotomoy (POEM); Submucosal Tumor Endoscopic Resection; Endoscopic Full Thickness Resection; Submucosal Tunneling for NOTES Procedures Beyond Resection; Pyloromyotomy; New NOTES: Western Perspective; and Why Did the Old NOTES Fail: Lessons Learned that can Guide New NOTES Development.