The European College of Neuropsychopharmacology (ECNP) is a scientific and educational association which represents a variety of disciplines. The first ECNP congress took place in Copenhagen, May 1985, where a working group of European scientists within the field of psychopharmacology was elected to prepare a constituent ECNP congress in Brussels, 1987. Among the most active members of this group was Max Hamilton. At the second ECNP congress in Brussels Max Hamilton was elected as the first honorary member of the ECNP. When we received the message of his death we decided at once to arrange a Max Hamilton memorial symposium at the third ECNP congress, May 1989, in Gothenburg, Sweden. This monograph contains the proceedings of the Max Hamilton symposium which was chaired by the editors. The opening lecture of the third ECNP congress was a Max Hamilton lecture: "A life devoted to science in psychiatry" which was presented by Sir Martin Roth. It seemed obvious to include Sir Martin's lecture as the opening article of this monograph. Although G .E. Berrios was unable to participate in the ECNP congress we have found it logical to include his manuscript on "The Hamilton Depression Scale and the Numerical Description of the Symptoms of Depression" as another personal contribution to Max Hamilton and his rating scales.

The Hamilton Depression (HAM-D) and Anxiety (HAM-A) scales are the most widely used instruments for measuring outcome in mood disorders. The Zung scales have also been widely used, especially in psychopharmacology; however, they have also been used to measure both negative and positive well-being in WHO studies in psychosomatic medicine. These scales were developed around three decades ago. In collaboration with Hamilton, the author has updated these scales to make them more applicable to the needs of health workers at all levels. The scoring sheets and the corresponding manuals of the scales are included along with the documentation of both internal (coherence) and external (discriminating and predictive) validity.

Worldwide economic constraints on health care systems have highlighted the importance of evidence-based medicine and evidence-based health policy. The resulting clinical trials and health services research studies require instruments to monitor the outcomes of care and the output of the health system. However, the over-abundance of competing measurement scales can make choosing a measure difficult at best. Measuring Health provides in-depth reviews of over 100 of the leading health measurement tools and serves as a guide for choosing among them.LNow in its third edition, this book provides a critical overview of the field of health measurement, with a technical introduction and discussion of the history and future directions for the field. This latest edition updates the information on each of the measures previously reviewed, and includes a complete new chapter on anxiety measurement to accompany the one on depression. It has also added new instruments to those previously reviewed in each of the chapters in the book.LChapters cover measurements of physical disability, social health, psychological well-being, anxiety, depression, mental status testing, pain, general health status and quality of life. Each chapter presents a tabular comparison of the quality of the instruments reviewed, followed by a detailed description of each method, covering its purpose and conceptual basis, its reliability and validity and, where possible, shows a copy of the actual scale. To ensure accuracy of the information, each review has been approved by the original author of each instrument or by an acknowledged expert.

For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now. Rating Scales in Parkinson's Disease is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another.

A comprehensive guidebook to the current methodologies and practices used in health surveys A unique and self-contained resource, Handbook of Health Survey Methods presents techniques necessary for confronting challenges that are specific to health survey research. The handbook guides readers through the development of sample designs, data collection procedures, and analytic methods for studies aimed at gathering health information on general and targeted populations. The book is organized into five well-defined sections: Design and Sampling Issues, Measurement Issues, Field Issues, Health Surveys of Special Populations, and Data Management and Analysis. Maintaining an easy-to-follow format, each chapter begins with an introduction, followed by an overview of the main concepts, theories, and applications associated with each topic. Finally, each chapter provides connections to relevant online resources for additional study and reference. The Handbook of Health Survey Methods features: 29 methodological chapters written by highly qualified experts in academia, research, and industry A treatment of the best statistical practices and specific methodologies for collecting data from special populations such as sexual minorities, persons with disabilities, patients, and practitioners Discussions on issues specific to health research including developing physical health and mental health measures, collecting information on sensitive topics, sampling for clinical trials, collecting biospecimens, working with proxy respondents, and linking health data to administrative and other external data sources Numerous real-world examples from the latest research in the fields of public health, biomedicine, and health psychology Handbook of Health Survey Methods is an ideal reference for academics, researchers, and practitioners who apply survey methods and analyze data in the fields of biomedicine, public health, epidemiology, and biostatistics. The handbook is also a useful supplement for upper-undergraduate and graduate-level courses on survey methodology.

The COVID-19 pandemic is unlike anything the world has ever seen before. Its reach is wide, and its effects have been debilitating. Understanding this particular strain of the coronavirus and knowing the best ways to recover are more important than ever. Rehabilitation from COVID-19: An Integrated Traditional Chinese and Western Medicine Protocol contains basic knowledge about COVID-19, including its etiology, pathogenesis, and treatment both in traditional Chinese medicine and Western medicine. It also includes relative assessment and rehabilitation targeting residual dysfunctions due to COVID-19, such as pulmonary dysfunction, mental disorders, and malnutrition, among others. Key Features Presents a new concept of CRN (COVID-19 Rehabilitation Unit) that will protect patients and medical workers Emphasizes special management of rehabilitation procedures under COVID-19 conditions Includes home-based rehabilitation tactics Provides assessment scales to help patients self-evaluate Based on clinical experience from experts, this text has been compiled by those on the frontline against COVID-19 in Wuhan. Rehabilitation from COVID-19 is an informative collection that will be helpful to patients and medical workers alike.

Aims to provide an accessible and practical guide to the assessment, differentiation and clinical management of the emotional and psychosocial problems of aphasic and non-aphasic brain damaged individuals and their families. Current clinical approaches are also considered.

"This volume addresses the assessment of the most commonly encountered disorders or conditions among adults, older adults, and couples. Evidence-based strategies and instruments for assessing mood disorders, anxiety disorders, couple distress and sexual problems, health-related problems, and many other conditions are covered in depth. With a focus throughout on assessment instruments that are feasable, psychometrically sound, and useful for typical clinical practice, a rating system has been designed to provide evaluations of a measure's norms, reliability, validity, and clinical utility. Standardized tables summarize this information in each chapter, providing essential information on the most scientifically sound tools available for a range of assessment needs."--BOOK JACKET.

Drug Safety Evluation Comprehensive and practical guide presenting a roadmap for safety assessment as an integral part of the development of drugs and therapeutics This fourth edition of Drug Safety Evaluation maintains the central objective of presenting an all-inclusive practical guide for those who are responsible for ensuring the safety of drugs and biologics to patients, healthcare providers, those involved in the manufacture of medicinal products, and all those who need to understand how the safety of these products is evaluated and shepherding valuable candidates to market. Individual chapters address specific approaches to evaluation hazards, including problems that are encountered and their solutions. Also covered are the scientific and philosophical bases for evaluation of specific concerns (e.g., carcinogenicity, development toxicity, etc.) to provide both understanding and guidance for approaching the new problems that have come to face both our society and the new challenges they brought. The many changes in regulatory requirements, pharmaceutical development, technology, and the effects of Covid on our society and science have required both extensive revision to every chapter and the addition of four new chapters. Specific sample topics covered in Drug Safety Evaluation include: The drug development process and the global pharmaceutical marketplace and regulation of human pharmaceutical safety Sources of information for consideration in study and program design and in safety evaluation Electronic records, reporting and submission, screens in safety and hazard assessment, and formulations, routes, and dosage regimens Mechanisms and endpoints of drug toxicity, pilot toxicity testing in drug safety evaluation, and repeat dose toxicity Genotoxicity, QSAR tools for drug safety, toxicogenomics, nonrodent animal studies, and developmental and reproductive toxicity testing An appendix which provides an up to date guide to CROs for conducting studies Drug Safety Evaluation was written specifically for the pharmaceutical and biotechnology industries, including scientists, consultants, and academics, to show a utilitarian yet scientifically valid path to the everyday challenges of safety evaluation and the problem solving that is required in drug discovery and development.