The definitive reference work, this book combines detailed scientific accuracy with a classical style, erudition, and an appealing presentation. It covers the past, present, and future trends in endocrinology, and includes biographies of major figures. It provides chronological tables and name and subject indexes that make the information easily accessible.

International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity. The authors discuss in detail their diagnosis, clinical manifestations, complications, and best practices for diagnosis and treatment. They also review the history and epidemiology of these conditions, explain their genetics and pathophysiology, and illuminate their known mechanisms and interactions. State-of-the-art survey-chapters critique current approaches (lifestyle and pharmacological) to the treatment of these conditions.

Diabetes mellitus is a very common disease which affects approximately 150,000,000 worldwide. With its prevalence rising rapidly, diabetes continues to mystify and fascinate both practitioners and investigators by its elusive causes and multitude of This textbook is written for endocrinologists, specialists in other disciplines who treat diabetic patients, primary care physicians, housestaff and medical students. It covers, in a concise and clear manner, all aspects of the disease, from its pathogenesis on the molecular and cellular levels to its most modern therapy.

General and Comparative Endocrinology: An Integrative Approach, takes a holistic approach to endocrinology, introducing students to the diverse facets of this interdisciplinary science ranging from the medical to comparative domains, while also exploring evolutionary, environmental, and conservation specializations within the field. The textbook is founded on the principle that students interested in the health sciences will benefit from understanding how proficiency in endocrine function among a diversity of organisms contributes to advances in modern medicine. Likewise, students intrigued by comparative physiology will benefit from the wealth of knowledge derived from medical/clinical endocrinology, the historical bedrock of the field. This textbook represents the modern field of endocrinology in its totality by addressing topics and recent advances not currently discussed in other introductory endocrinology textbooks. Key Features Introduces the broad and interdisciplinary scope of endocrinology. Provides clear chapter objectives and key concepts. Includes summary and synthesis questions for each chapter that are suitable for exams and quizzes. Includes a chapter devoted to endocrine-disrupting chemicals. Describes the roles played by the endocrine system in important health challenges related to appetite regulation, obesity, diabetes, and other diseases stemming from ‘mismatches to modernity’. Integrates evolutionary and comparative approaches to hormones and health.

The Reader's Guide to the History of Science looks at the literature of science in some 550 entries on individuals (Einstein), institutions and disciplines (Mathematics), general themes (Romantic Science) and central concepts (Paradigm and Fact). The history of science is construed widely to include the history of medicine and technology as is reflected in the range of disciplines from which the international team of 200 contributors are drawn.

Studies in Natural Products Chemistry, Volume 55 covers rapid developments in spectroscopic techniques, also presenting advances in high-throughput screening techniques, including the new potential to isolate and determine the structures and biological activity of natural products and their applications in the field of new drug development. This ongoing series covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores

Hormones play an integral part in the balance and workings of the body. While many people are broadly aware of their existence, there are many misconceptions and few are aware of the nature and importance of the endocrine system. In this Very Short Introduction, Martin Luck explains what hormones are, what they do, where they come from, and how they work. He explains how the endocrine system operates, highlighting the importance of hormones in the regulation of water and salt in the body, how they affect reproduction and our appetites, and how they help us adjust to different environments, such as travel across time zones. In this fresh and modern treatment, Luck also touches on the ethical and moral issues surrounding research methods, testing on animals, and hormone misuse. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Diabetes mellitus is probably one of the oldest diseases known to mankind. This book covers not only the action, pathogenesis, epidemiology, prevention, and treatment of disease but also encompasses the same regarding all its complications such as diabetic neuropathy, diabetic foot, diabetic kidney disease, stroke, hypertensive emergencies, gestational diabetes mellitus, maternal and foetal morbidity associated with gestational diabetes mellitus, intrapartum management and postpartum follow up. The writer provides authoritative, comprehensive, concept-oriented, clinically-applicable text concisely for easy understanding and assimilation by readers.

Fat in the Fifties is required reading for public health practitioners and researchers, physicians, historians of medicine, and anyone concerned about weight and weight loss.

"This timely history tells the story of how 'gender' was invented in American medicine. The concept of gender shifted from a pragmatic tool in the sex assignment of children with intersex traits in the 1950s to an essential category in clinics for transgender patients in the 1960s, to a feature of feminist debates about the sex/gender binary in the 1970s, to the word we know today. Our current idea of gender might not map exactly onto these earlier formulations, but we still live with the legacy of this genealogy. Sandra Eder reveals that there was-without a doubt- something new, transformative, and enduring about the concept of gender that developed through clinical practices at pediatric endocrinology clinics. The history of gender laid out in this book shows that these ideas held no single, unified meaning-neither within the clinic nor outside it-and that 'gender' was shaped by the behaviors and needs of those who used and adapted it. This is not a neat and tidy story about the introduction of a liberating concept. Nor does this book simply focus on the development of a medical regime that subjected intersex infants to irreversible genital surgery. Rather, How the Clinic Made Gender explores the shifting landscapes of discussion about sex, gender, and sexuality in modern US history. The process by which ideas about gender became medicalized, enforced, and popularized was messy, and how gender came to be understood and applied through the treatment of patients with intersex traits was fraught and contested. This book is about the intricate ways in which the most intimate of ideas were put into practice in medicine and how those clinical practices, in turn, have informed our ideas about gender to this day"--