Understanding immunology is increasingly important in obstetrics and gynecology. Written primarily to meet the needs of practicing obstetricians and gynecologists, this book explores the role of immunological processes in reproduction. It presents immunologic concepts and illustrates important points with examples familiar to the clinician. The boo

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"This volume presents the highlights of current global thinking about sexual and reproductive health. Major changes have taken place in the last 15 years in the way decision-makers think about the subject and the manner in which programmes deliver comprehensive sexual and reproductive health services. The turning point was the International Conference on Population and Development (ICPD) held in Cairo, Egypt, in 1994. ICPD was a watershed for several reasons. First, more than in any of the preceding United Nations population conferences, the issue of population was clearly placed as being central to sustainable development. Second, the narrow focus on population growth ("the population bomb") which had been a neo-Malthusian concern and preoccupation ever since the Club of Rome published its 1972 report Limits to Growth, was replaced by the comprehensive concept of (sexual and) reproductive health. Third, and linked to the definition and introduction of the reproductive health concept, was the strong call for a paradigm shift away from a policy environment driven by demographic considerations (sometimes to the point of using coercion in family planning services in order to reach demographic targets) to an environment that recognized the right of individuals to make their own choices. And, last but not least, ICPD as well as the Fourth World Conference on Women (FWCW) held the following year in Beijing, People's Republic of China, strongly emphasized that the rights of women and men to good sexual and reproductive health are firmly grounded in universal human rights"--Provided by publisher.

The index is based on citations selected from the corresponding monthly issue of Index medicus.

Mucosal Immunology, now in its fourth edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. Most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes, making this subject an area of singular importance in the field of immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective, and excellent organization. It covers immune system topics, such as inductive and effector tissues and cells, and development and physiology of the mucosal barrier; diseases in the digestive system, respiratory tract, and genitourinary tract; and immunodeficiency. - The most comprehensive text on mucosal immunology from internationally recognized experts in the field - Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases - Contains nine new chapters and an expanded appendix

Toll-like receptors (TLRs) have attracted interest due to their role in detecting pathogens and regulating the pro-inflammatory immune response. To date, 10 functional TLRs (TLR1–10) have been detected in humans. These TLRs control diverse immunological and embryonic development processes to maintain immune homeostasis and healthy fetal growth and development. They recognize diverse pathogen-associated molecular patterns (PAMPs) and death/damage-associated molecular patterns (DAMPs) to maintain immune homeostasis via regulating diverse immunological processes. This book discusses TLRs from their evolution to immunological functions governing infection and inflammation pathogenesis, cancer immunology, and their interactions with other pro-inflammatory molecules generated during inflammation pathogenesis. It is a must-read for researchers interested in TLR biology and the role of TLRs in infection, immunity, and cancer.

As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following words: “Complement, does that really exist?” I was never certain whether he wanted only to tease me or whether he sincerely believed that the complement system was an unimportant biological curiosity, a misstep of evolution. But, of course, missteps do not survive the evolutionary process. Little did I foresee the dramatic developments of recent years when Hans J. Müller-Eberhard and I started to unravel the specifics of the action of the cobra venom factor on the complement system in 1968 and defined a new pathway to its activation. An elucidation of the role of the system in diseases and its control for therapeutic reasons is now getting closer to actual realization in the clinic although many problems, in particular those of highly specificinhibition free of side effects, have still to be resolved.

A scientific and evidence-based guide to understanding early pregnancy development and clinical management.