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The human immune system is a complicated biological network that employs a collection of cells, molecules, and proteins. Cytokines play an important role in regulating the innate and adaptive immune systems by different receptors and signaling pathways. As such, they are also implicated in the occurrence of different disorders and diseases. This book presents a comprehensive overview of immunology, the immune system, and cytokines. Chapters cover such topics as the role and importance of tumor necrosis factor (TNF) in the human body, the association of cytokines with different disorders and diseases, and the role of cytokines in dentistry.

"[F]or those who are entering the field or who want to broaden their perspective, Ibelieve that this Handbook is indispensible. More than just a contribution to the field, theHandbook may well become a classic."--PsycCRITIQUES "The editors fully achieved their goal of producing a state-of-the-science stress reference for use by investigators, educators, and practitioners with clinical and health interests."--Psycho-Oncology "This is an important book about the scientific study of stress and human adaptation. It brings together both empirical data and theoretical developments that address the fundamental question of how psychosocial variables get inside the body to influence neurobiological processes that culminate in physical disease." From the Foreword by David C. Glass, PhD Emeritus Professor of Psychology Stony Brook University Edited by two leading health psychologists, The Handbook of Stress Science presents a detailed overview of key topics in stress and health psychology. With discussions on how stress influences physical health-including its effects on the nervous, endocrine, cardiovascular, and immune systems-the text is a valuable source for health psychologists, as well as researchers in behavioral medicine, neuroscience, genetics, clinical and social psychology, sociology, and public health. This state-of-the-art resource reviews conceptual developments, empirical findings, clinical applications, and investigative strategies and tools from the past few decades of stress research. It represents all major approaches to defining stress and describes the themes and developments that characterize the field of health-related stress research. The five sections of this handbook cover: Current knowledge regarding the major biological structures and systems that are involved in the stress response Social-contextual contributions to stress and to processes of adaptation to stress, including the workplace, socioeconomic status, and social support The concept of cognitive appraisal as it relates to stress and emotion psychological factors influencing stress such as, personality, gender, and adult development The evidence linking stress to health-related behaviors and mental and physical health outcomes Research methods, tools, and strategies, including the principles and techniques of both laboratory experimentation and naturalistic stress research

This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.