Barely four years after winning an Oscar, Charlie has sunk into the ranks of Hollywood bottom-feeders -- reduced to living in his nephew's pool house, kiting checks and taking the bus to his weekly Debtors Anonymous meeting, where he meets a mysterious ex-CIA agent who proposes to resuscitate Charlie's foundering career -- in the beyond surreal world of reality TV. Charlie puts his tap shoes on to sell a show about a ruthless Uzbek warlord and his family ("think The Osbournes meets The Sopranos") to a rogue division of ABC, known as ABCD, which operates out of a skunkworks in Manhattan Beach, California, and whose mandate is to develop, under top secret cover like that for the Manhattan Project, extreme reality TV shows to bolster the network's ratings. Warlord becomes a breakout hit and results not only in causing one of America's largest entertainment conglomerates to go into full damage-control mode but also in shifting the balance of power in Central Asia and in proving that in show business it's not over till the mouse sings.

An isolated ocean-view village on the dunes above South Santa Monica Bay, Manhattan Beach grew with the arrival of railroads. This quaint, upscale jewel of the Los Angeles County coast has been known for its cottage-style living, the Metlox Pottery Company and the iconic pier. These diverse stories mix the city's controversies, including the still unsolved 1936 murder of Reid Russell, with true tales of pioneering women, controversial politics and the vicissitudes of seaside city development. Join author Jan Dennis, a former Manhattan Beach city mayor, on this illuminating tour through the issues and eras of her beloved city's history.

Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.

Th is book is a ground breaking review of the three most important scientifi c areas of anti-aging medicine. Stephen Holt MD has navigated areas of conventional and integrative medicine to produce a book that is valuable for both a layperson and biomedical experts.