During the past years there has been rapid progress in the understanding of how early life stress impacts psychopathology in children. The first two parts of this book present the basic principles of brain development and describe the most important neuronal systems. This includes systems involved in emotion processing, cognitive control, and social processes. These first two general sections are followed by an overview about recent research on various neuronal and psychiatric disorders, where environmental exposures and altered brain development play an important role: sleep, autism, ADHD and other developmental forms of psychopathology.

"This valuable, reader-friendly book helps parents, teachers, and others who work with young children understand the complex and amazing processes involved as the young brain grows and develops." —David A. Sousa, Consultant in Educational Neuroscience, Author of How the Brain Learns "The book reminds us of the importance of nurturing children. We need to help children develop from their core, even if that development cannot be measured on a test." —Sonia Trehan Kelly, Director, Blue River Montessori School, Duxbury, MA Learn how a child′s brain works, develops, and changes during the critical stages of childhood! Robert Sylwester, author of 10 books, has written this volume to help parents and educators understand children′s cognitive development and provide suggestions on how to nurture children to their full potential. A companion to The Adolescent Brain, this rich resource: Examines the neurobiology of childhood, explaining the body/brain systems that develop during pregnancy, infancy, and childhood Explores factors that can enhance or delay development, such as nutrition, family life, relationships, illness, intelligence, technology, creativity, and the arts Provides practical suggestions to help adults promote healthy development and successful learning in the children they encounter Includes a glossary of neurobiological terms A Child′s Brain helps parents and educators understand the biological, emotional, and neurological changes that occur during childhood so they can support children′s learning, socialization, and growth.

In addition to filling a need within the field of parental behavior, this book contributes importantly to the growing area of emotional and motivational neuroscience. A major part of neuroscience research at the whole organism level has been focused on cognitive neuroscience, with an emphasis on the neurobiology of learning and memory, but there has been a recent upsurge in research which is attempting to define the neural basis of basic motivational and emotional systems which regulate such behaviors as food intake, aggression, reproduction, reward-seeking behaviors, and anxiety-related behaviors. In this book the emphasis is on the research findings obtained from rodents, sheep and primates. The authors' goal, of course, was to provide a foundation that may help us understand the neurobiology of human parental behavior. Indeed, the last chapter attempts to integrate the non-human research data with some human data in order to make some inroads toward an understanding of postpartum depression, child abuse, and child neglect. Clearly, motivational and emotional neuroscience has close ties to psychiatry, and this connection will be very evident in the final chapter. By understanding the neurobiology of parental behavior we are also delving into neurobiological factors which may have an impact on core human characteristics involved in sociality, social attachment, nurturing behavior, and love. In this very violent world, it is hard to conceive of a group of characteristics that are more worthy of study.

The Neurobiology of Brain and Behavioral Development provides an overview of the process of brain development, including recent discoveries on how the brain develops. This book collates and integrates these findings, weaving the latest information with core information on the neurobiology of brain development. It focuses on cortical development, but also features discussions on how the other parts of the brain wire into the developing cerebral cortex. A systems approach is used to describe the anatomical underpinnings of behavioral development, connecting anatomical and molecular features of brain development with behavioral development.The disruptors of typical brain development are discussed in appropriate sections, as is the science of epigenetics that presents a novel and instructive approach on how experiences, both individual and intergenerational, can alter features of brain development. What distinguishes this book from others in the field is its focus on both molecular mechanisms and behavioral outcomes. This body of knowledge contributes to our understanding of the fundamentals of brain plasticity and metaplasticity, both of which are also showcased in this book. Provides an up-to-date overview of the process of brain development that is suitable for use as a university textbook at an early graduate or senior undergraduate level Breadth from molecular level (Chapters 5-7) to the behavioral/cognitive level (Chapters 8-12), beginning with Chapters 1-4 providing a historical context of the ideas Integrates the neurobiology of brain development and behavior, promoting the idea that animal models inform human development Presents an emphasis on the role of epigenetics and brain plasticity in brain development and behavior

The second edition of Neurobiology of Disease includes nearly 200 articles surveying all major disorders of the nervous system in both adults and children, focusing on relevant diagnosis and treatments from the perspective of cutting edge clinical and basic neurobiological research. Akin to an encyclopedia of every neurologic disorder, this comprehensive work is ideal for graduate and medical school students, residents, and candidates preparing for their board certification examinations. Each chapter is illustrated with detailed figures, supplemented with descriptive and diagnostic tables, and thoroughly referenced for further investigations. The book's editors, Michael V. Johnston, Harold P. Adams Jr., and Ali Fatemi bring their unique expertise in clinical and research neurology to the overall scope of this work. To further enhance the scope and quality of this new edition, the following Section Editors provided oversight of their respective sections: · Movement Disorders-Joel Perlmutter, Washington University · Dementias-David Knopman, Mayo Clinic · Motorneuron Diseases-Merit Cudkowicz, Massachusetts General Hospital · Paroxysmal Disorders-Solomon Moshe, Albert Einstein College of Medicine · Pediatric Neurology and Developmental Disorders-Tanjala Gipson and Deepa Menon, Kennedy Krieger Institute and Johns Hopkins University · Neuroimmunological Diseases-Carlos Pardo-Villamizar, Johns Hopkins University · Cerebrovascular Diseases-Harold P. Adams Jr., University of Iowa · Peripheral and Autonomic Nervous System Disorders and Pain-Nicholas Maragakis, Johns Hopkins University · Neoplastic and Paraneoplastic Diseases-Lisa DeAngelis, Memorial Sloan-Kettering Cancer Center · Infectious Diseases of the Nervous System-Karen L. Roos, Indiana University · Sleep Disturbances-Mark Dyken, University of Iowa · Substance Abuse and Toxicology Disorders-Barry E. Kosofsky, Weill-Cornell University Medical Center · Neurologic Manifestations of Medical Disorders-John C. Probasco, Johns Hopkins University

From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.

Nurture or nature? Biology or environment? Why are some people intelligent, or personable, or creative and others obtuse, or shy, or unimaginative? Although each human being is a unique mixture of positive and negative traits and behaviors, the question remains: What is the neurobiological basis for each individual’s makeup? For example, why does one person suffer from a disorder (e.g., ADHD, autism, mental retardation) and another lives free of maladies? These are just some of the issues addressed in detail in Neurobiology of Exceptionality. The introductory chapter provides a broad-based overview of current neurobiological techniques (i.e., terms, procedures, and technologies), which are followed by chapters that offer in-depth examination of the neurobiological bases for: • Impulsive sensation seeking • Creativity • Intelligence • Antisociality • Autism, mental retardation, and Down Syndrome • ADHD • Savant Syndrome This volume provides a one-stop source for clinical psychologists and other allied mental health professionals to access information on a wide range of research on the neurobiology of psychological and psychiatric traits. It is designed to give readers an overview of the current knowledge base of the biological processes for each trait. It is unlikely that any one book could cover all human traits, but the Neurobiology of Exceptionality addresses a wide range of exceptional psychological traits and psychiatric disorders.

Child Neurology: Its Origins, Founders, Evolution and Growth, Second Edition updates the first biographical study of important contributors to the field of child neurology, consisting of over 250 biographical sketches written by over 100 physicians specializing in neurology, child neurology, pediatrics and obstetrics. Organized chronologically into six chapters, beginning before 1800 and continuing to the present, Child Neurology traces the emergence of child neurology as a separate specialty from its roots in pediatrics and neurology. With a definitive historical introduction by the editor, Dr. Stephen Ashwal. This new edition will feature a new section on The Dynamic Growth and Expansion of Child Neurology: The Late Twentieth Century (1960 to 2000+) and features about 138 new biographical sketches of leaders in the field during this recent time frame. Child Neurology: Its Origins, Founders, Evolution and Growth, Second Edition will be published on behalf of the Child Neurology Society, a professional society that strives to foster recognition and support for children with neurological disorders and to promote and exchange national and international scientific research, education, and training in the field of neurology. - Identifies top contributors to child neurology research from the 1800s to today - Includes 238 biographical sketches of contributors and their scientific research - Contains 138 new biographies on contributors from the late 20th and early 21st centuries - Authored by physicians and published by the Child Neurology Society

A practical, dynamic resource for practicing neurologists, clinicians and trainees, Bradley and Daroff's Neurology in Clinical Practice, Eighth Edition, offers a straightforward style, evidence-based information, and robust interactive content supplemented by treatment algorithms and images to keep you up to date with all that's current in this fast-changing field. This two-volume set is ideal for daily reference, featuring a unique organization by presenting symptom/sign and by specific disease entities—allowing you to access content in ways that mirror how you practice. More than 150 expert contributors, led by Drs. Joseph Jankovic, John C. Mazziotta, Scott L. Pomeroy, and Nancy J. Newman, provide up-to-date guidance that equips you to effectively diagnose and manage the full range of neurological disorders. - Covers all aspects of today's neurology in an easy-to-read, clinically relevant manner. - Allows for easy searches through an intuitive organization by both symptom and grouping of diseases. - Features new and expanded content on movement disorders, genetic and immunologic disorders, tropical neurology, neuro-ophthalmology and neuro-otology, palliative care, pediatric neurology, and new and emerging therapies. - Offers even more detailed videos that depict how neurological disorders manifest, including EEG and seizures, deep brain stimulation for PD and tremor, sleep disorders, movement disorders, ocular oscillations, EMG evaluation, cranial neuropathies, and disorders of upper and lower motor neurons, as well as other neurologic signs. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

In Neurology of Autism, Mary Coleman, Catalina Betancur, G. Robert DeLong, Christopher Gillberg, Yoshiko Nomura, Lorenzo Pavone, Martin Ruggieri, and Michele Zappella use the tools of neurological analysis to address a number of the major questions that have arisen in the study of autism. The answers they present have important implications for the direction of future autism research, diagnosis, and treatment. What are the neurological signs and symptoms of autism? The latest information is presented here in an in-depth discussion of epilepsy, cranial circumference, changes in muscle tone, stereotypies, and mutism found in children with autism. In addition, a template is provided for practitioners to follow when conducting neurological examinations of a child with autism. What are the best options for the treatment of autism? The current medical, educational, and alternative therapies are thoroughly reviewed and evaluated. Is autism reversible? The question is explored for syndromic autism, where diseases may have a transient autistic phase, and reviewed in detail for nonsyndromic autism. Is autism primarily a single disease, as originally described by Leo Kanner? Research presented here suggests that autism is, instead, a syndrome involving many disease entities. Has the incidence of autism been increasing in recent years? A sophisticated, historical review of autisms prevalence rates suggests that it has never been rare. What is the relationship between autism and Asperger syndrome? The latest evidence presented here sheds light on the degree to which both syndromes share more than clinical characteristics; they also have some similar findings in imaging, neuropathological, and genetic studies. Which components of the brains neural networks need to be impaired to cause the appearance of autistic symptoms? Although there are many candidate regions, dysfunction of the cerebellum and its circuits is noted to be of great interest. Student and professional researchers, practitioners, and parents will find this book to be a valuable resource for both the latest information from basic-science research and its application to the diagnosis and treatment of autism. "[This book] includes up-to-date genetic evidence, underlining the complexities of genetic/environmental influences...I recommend this easy and informative read." -European Journal of Pediatric Neurology "...authoritative." -The Lancet Neurology "Coleman's new book is an absolute must-read for anyone interested in the progress made in understanding the causes of autism. The field owes her a tribute worthy of someone who has transformed an area of neuroscience." -Simon Baron-Cohen in Nature Neuroscience "[I]nformative and comprehensive in its treatment of the neurologic basis of autism...well written and easy to understand...the contributing authors have done an excellent job of making complex medical concepts understandable to all. The glossary at the end of the book is extremely helpful in this regard. The book is well referenced, provides helpful tables throughout, and includes a summary of relevant points at the end of each chapter.The authors are to be commended for presenting a very balanced view of current knowledge; they also indicate what we do not yet understand about brain functioning in autism and provide an important road map for ongoing exploration." -Marshalyn Yeargin-Allsopp in The New England Journal of Medicine "At last it is recognised that developmental neurology is the appropriate context in which to explain autism. The authors of this volume, all pioneers in the field, consider new ideas on autism in this context. They succeed in making surprising and illuminating comparisons between autism and neurological disorders whose origin is already known. This work is a significant step towards understanding the causes of autistic disorders."-Uta Frith, Institute of Cognitive Neuroscience and Department of Psychology, University College London "When and if the secret of autism is teased from the myriad disease states that exhibit the syndrome, it will be through efforts such as are represented in this volume. Dr. Coleman has 'picked the brains' of recognized experts from neurology and related sciences, and has assembled a wealth of up-to-date and meticulously referenced information regarding both those diseases and the core symptoms of autism." -Peter B. Rosenberger, Massachusetts General Hospital