Substance use and substance use disorders (SUDs) have been documented in a number of cultures since the beginnings of recorded time and represent major societal concerns in the present day. The Oxford Handbook of Substance Use and Substance Use Disorders provides comprehensive reviews of key areas of inquiry into the fundamental nature of substance use and SUDs, their features, causes, consequences, course, treatment, and prevention. It is clear that understanding these various aspects of substance use and SUDs requires a multidisciplinary perspective that considers the pharmacology of drugs of abuse, genetic variation in these acute and chronic effects, and psychological processes in the context of the interpersonal and cultural contexts. Comprising two volumes, this Handbook also highlights a range of opportunities and challenges facing those interested in the basic understanding of the nature of these phenomena and novel approaches to assess, prevent, and treat these conditions with the goal of reducing the enormous burden these problems place on our global society. Chapters in Volume 1 cover the historical and cultural contexts of substance use and its consequences, its epidemiology and course, etiological processes from the perspective of neuropharmacology, genetics, personality, development, motivation, and the interpersonal and larger social environment. Chapters in Volume 2 cover major health and social consequences of substance involvement, psychiatric comorbidity, assessment, and interventions. Each chapter highlights key issues in the respective topic area and raises unanswered questions for future research. All chapters are authored by leading scholars in each topic. The level of coverage is sufficiently deep to be of value to both trainees and established scientists and clinicians interested in an evidenced-based approach.

The Oxford Handbook of Substance Use and Substance Use Disorders provides comprehensive reviews of key areas of inquiry into the fundamental nature of substance use and SUDs, their features, causes, consequences, course, treatment, and prevention.

Adolescent substance abuse is the nation's #1 public health problem. It originates out of a developmental era where experimentation with the world is increasingly taking place, and where major changes in physical self and social relationships are taking place. These changes cannot be understood by any one discipline nor can they be described by focusing only on the behavioral and social problems of this age period, the characteristics of normal development, or the pharmacology and addictive potential of specific drugs. They require knowledge of the brain's systems of reward and control, genetics, psychopharmacology, personality, child development, psychopathology, family dynamics, peer group relationships, culture, social policy, and more. Drawing on the expertise of the leading researchers in this field, this Handbook provides the most comprehensive summarization of current knowledge about adolescent substance abuse. The Handbook is organized into eight sections covering the literature on the developmental context of this life period, the epidemiology of adolescent use and abuse, similarities and differences in use, addictive potential, and consequences of use for different drugs; etiology and course as characterized at different levels of mechanistic analysis ranging from the genetic and neural to the behavioural and social. Two sections cover the clinical ramifications of abuse, and prevention and intervention strategies to most effectively deal with these problems. The Handbook's last section addresses the role of social policy in framing the problem, in addressing it, and explores its potential role in alleviating it.

This handbook reviews research and clinical developments through synthetic chapters written by experts from various fields of study and clinical backgrounds. It discusses each of the main anxiety disorders and examines diagnostic criteria, prevalence rates, comorbidity, and clinical issues.

Opioids have played a prominent role in society for centuries and have been lauded for both their analgesic and euphoric qualities by cultures throughout the world. The advent of medical and pharmaceutical sciences in the 20th century ushered in a wide variety of different commercial opioid products that were designed to maximize their therapeutic potential. As the use of opioids increased, a corresponding need emerged to understand more about how opioids exert their effects in the body and brain; the consequences of opioid use regarding physical dependence, withdrawal, and craving; how we might best treat opioid use disorder (OUD) and address risk for opioid-related overdose; and how opioids may intersect with other clinical conditions to produce unique challenges. Edited by Kelly E. Dunn, The Oxford Handbook of Opioids and Opioid Use Disorder synthesizes research across the spectrum, and establishes a foundational knowledge regarding historical and current epidemiological trends, neurobiological and genetic contributors to opioid effects and OUD, and core elements of opioid use such as withdrawal and craving. It provides specific information and guidance regarding opioid treatment paradigms, including chapters on specific pharmacotherapies as well as treatment approaches, and discusses considerations for special clinical populations. An overview of these respective issues is provided across 38 chapters, which outline the history and science of these topics alongside clinical considerations and case examples. Written by expert bench scientists, epidemiologists, clinical trial interventionists, medical practitioners, and harm reduction specialists, this handbook will serve as a comprehensive guide for practitioners, policymakers, students, and researchers who wish to achieve a better understanding of the complex world of opioid and OUD practice and science.

Psychoactive substance use ranks among the five top risk factors contributing to the global burden of disease. Substance use disorders can cause, mimic, underlie, or complicate a large number of medical and psychiatric conditions. In recent years, there has been a rapid increase in non-substance forms of addiction such as gambling, internet gaming, and various other behavioural addictions. The ability to diagnose addictive disorders and initiate appropriate management is a responsibility for all health professionals. Addiction Medicine, now in its third edition and published in the renowned Oxford Medical Handbook series, is the result of many years' preparation by a group of colleagues who are clinicians, teachers, and researchers in the addictive disorders field. The handbook is a contemporary, broadly-based, and clinically grounded text that summarises the scientific basis and practice of addiction medicine. It provides practical guidance on clinical management but with a sound background of pharmacology, neurobiology, psychology, and epidemiology and public health. It seeks to provide approaches to minimising harm from psychoactive substances and addictive behaviours, both at an individual and a societal level. The new edition has been expanded greatly. In addition to the behavioural addictions, it covers a broader range of psychoactive substances. There are new chapters on Screening and brief interventions and on Digital health approaches. It also continues to be international in scope, with the editors and contributors drawn from over 30 countries worldwide. The handbook is intended as a concise and practical guide for students, trainees, and qualified practitioners of medicine, nursing, psychology, and other health professionals. In particular, it is designed for students and post-graduate trainees and fellows in addiction medicine, internal medicine, psychiatry, emergency medicine, pain management, gastroenterology, and general medical (family physician) practice. It is also useful and relevant to nurses, particularly those working as specialists in addictive disorders, clinical psychologists, psychologists and counsellors, and social workers and for staff in multidisciplinary agencies which provide help, support, and treatment for people with addictive disorders. This unparalleled guide contains everything you need to know to assist in the assessment, diagnosis, and clinical management of patients with substance use and related addictive disorders

Depression is frequently associated with other psychiatric disorders and is often related to chronic health problems. Depressive symptoms are also common in chronically distressed close relationships and severe interpersonal difficulties in families and at work. The topic of depressive comorbidity is clearly very important, and while recent research in this area has been methodologically sophisticated, well presented, and inherently interesting, there has not been a comprehensive, academic resource that covers recent developments in this area. The Oxford Handbook of Depression and Comorbidity brings together scholarly contributions from world-class researchers to present a careful and empirically based review of depressive comorbidity. Cutting-edge chapters address theory, research, and practice, while capturing the diversity, evidence-base, and importance of depressive comorbidity. Specific topics include the comorbidity between depression and PTSD, alcohol use, and eating, anxiety, panic, bipolar, personality, and sleep disorders, as well as schizophrenia, suicide, cardiovascular disease, cancer, pain, obesity, intimate relationships, and many more. The Oxford Handbook of Depression and Comorbidity is a unique and much-needed resource that will be helpful to a broad range of researchers and practitioners including clinical and counseling psychologists, psychiatrists, marital and family therapists, social workers, and counselors working in mental-health and general health-care settings, as well as students in these areas.

The Oxford Handbook of Externalizing Spectrum Disorders is the first book of its kind to capture the developmental psychopathology of externalizing spectrum disorders by examining causal factors across levels of analysis and developmental epochs, while departing from the categorical perspective.

In The Oxford Handbook of Acceptance and Commitment Therapy, Michael P. Twohig, Michael E. Levin, and Julie M. Petersen bring together contributions from the world's leading scholars to create a comprehensive volume on established areas of ACT. The Handbook presents the first scholarly review of the treatment as it has developed over the past two to three decades. Featuring 33 chapters on key aspects of the treatment, the contributors offer analysis on ACT's conceptual and theoretical underpinnings, applications to specific populations and problems, methods of implementation, and other special topics. They will further cover theory, empirical support, and scholarly descriptions of treatment application.

This is the most comprehensive and detailed book about criminology ever published in the United Kingdom. It is designed to be immediately accessible to those interested in criminology who seek a way of familiarising themselves with the study of crime and criminality.