The publication of this volume of The Viruses entitled The Togaviridae and Flaviviridae comes at an appropriate time. The structure and rep lication strategies of these viruses are now known to be sufficiently di verse to warrant the removal of flaviviruses from the Togaviridae family and establish them as an independent family. Flaviviridae have a special place in the history of virology. The prototype virus-yellow fever virus was the first virus to be identified as the cause of a human disease. Some of the history of this discovery is described in Chapter 1 of this volume; in Chapter 10 the complete sequence of the RNA genome of the virus is presented. This sequence not only defines the primary structure of the viral proteins, it also clarifies the mechanism of translation of the fla vivirus genome. Knowledge of the sequence of the structural proteins of these viruses represents an important step in the potential goal of using purified flavivirus glycoproteins as vaccines. Many of the chapters in this volume focus on the structure and replication of the Togaviridae. These viruses have provided valuable models for studies in cell biology, partic ularly with regard to the cotranslational and posttranslational steps re quired for the synthesis and localization of membrane glycoproteins. Fur thermore, Togaviridae have been pivotal in our growing understanding of how enveloped viruses enter and exit from cells. The broad outlines of the structure and gene expression of Togavir idae and Flaviviridae are known, but important questions remain.

First Published in 2018. Routledge is an imprint of Taylor & Francis, an Informa company.

This text on electron microscopy in viral diagnosis is an invaluable reference investigators interested in the detection of viruses or viral subcomponents in liquid preparations or in thin sectioned cells. It contains an extensive collection of negative stain, thin section, and immunolabelled electron micrographs useful for reference viral diagnosis. The salient features of the replication of many virus families are presented in schematic form and all viruses now known to cause disease in humans, including the recently recognized human retroviruses, are described in separate chapter.

The Fifth Report of the International Committee on Taxonomy of Viruses (ICTV), summarizes the proceedings and decisions reached by the ICTV at its meetings held at the International Congresses of Virology in Sendai (1984), Edmonton (1987) and Berlin (1990). This report has been organized in the same way as the previous ones (Wildy, 1971; Fenner, 1976; Matthews, 1979; 1982), yet it encompasses many more families and groups of viruses than previous reports, and it includes new tables, diagrams and keys. The officers and members of the ICTV study groups from 1984 to 1990 are listed, as the current ICTV statutes and rules of nomenclature. Information on the format for submission of new taxonomic proposals to the ICTV is also provided. Since the Fourth Report of the ICTV (1982), 19 new virus families and groups have been described. This report includes 2,430 viruses belonging to 73 families or groups, as well as virus satellites and viroids descriptions, but it does not include descriptions not approved by the ICTV. It now will be possible to publish such preliminary, and in some cases controversial, descriptions in the Virology Division pages of the Archives of Virology --this will allow virologists to carry on the kind of interim dialogue that is necessary for arriving at broad agreement on taxonomic matters.

The Purpose of this book is to provide a helpful reference for invertebrate pathologist, virologists, and electron microscopists on invertebrate viruses. Investigators from around the world have shared their expertise in order introduce scientists to the exciting advances in invertebrate virology.

Veterinary Microbiology Comprehensive reference work on the bacterial, fungal, and viral pathogens that cause animal diseases Veterinary Microbiology, Fourth Edition presents comprehensive information based on the most recent research, diagnostic, and clinical publications for bacterial, fungal, and viral animal diseases. The information provided is intended to be most relevant for veterinary students and practitioners. The text is supported throughout by high-quality and full-color images to aid learning. A companion website offers chapter content, supplemental information, and figures from the book in PowerPoint format. Sample topics discussed within the book include: Pathogenic bacteriology: includes major classifications and genera of bacteria associated with veterinary infectious disease Pathogenic mycology: dermatophytes, agents of subcutaneous mycoses, and agents of systemic mycoses Pathogenic virology: includes RNA and DNA viruses as well as prions associated with veterinary infectious disease

From the difficult to diagnose to the difficult to treat, be prepared for whatever your patients bring back. The revised and updated 22nd edition of Manson’s Tropical Diseases provides you with the latest coverage on emerging and re-emerging diseases from around the world, such as multi-drug-resistant tuberculosis and malaria, the avian flu, and more. Boxes and tables highlight key information on current therapies. Covers every aspect of Tropical Medicine in detail, not just infections. Takes both a system-based and a disease approach, with extensive cross-referencing to minimize duplication. Includes a strong clinical focus, emphasized by clinical management diagrams. Features leading experts in the field, with contributions from clinicians who are based full-time in the tropics. Features up-to-date information on HIV/AIDS, with an emphasis on Africa; malaria; tropical gastroenterological problems; dengue and dengue hemorrhagic fever; tuberculosis; Sexually Transmitted Diseases; SARS; avian flu; bartonellosis, cat-scratch disease, trench fever, human erlichiosis; and more. Describes the latest therapies, such as recently approved drugs and new treatment options, so you can incorporate them into to your practice. Presents global perspectives from the world’s leaders in this specialty to put the latest expert knowledge to work for you and your patients. Highlights key information with more boxes and tables so you can find what you need easily and apply it quickly.

Providing the latest coverage on emerging and re-emerging diseases from around the world, such as tuberculosis and malaria, this updated guide contains boxes and tables that highlight key information on current therapies. This edition includes online access for more information.

those who deal with infectious diseases on a daily This two volume work stems from the belief of the Editors that infectious diseases are not only very basis. much with us today but, more importantly, that they There are several excellent textbooks dealing will continue to playa significant global role in mor with medical microbiology, and there are equally bidity and mortality in all people. A continuing need well-recognized books devoted to infectious dis for an informed and knowledgeable community of eases. The Editors of this work, on the other hand, were persuaded that there was a need for a publica laboratory scientists is fundamental. Data describing tion that would bring together the most pertinent and the global impact of infectious diseases are difficult to come by. Fortunately, a recent thoughtful and relevant information on the principles and practice of provocative publication by Bennett et al. (1987) pro the laboratory diagnosis of infectious diseases and vides us with data derived from several consultants include clinical relationships. While this two volume that clearly delineate the impact of infectious dis text is directed toward the role of the laboratory in eases on the United States today.