A savvy entrepreneur, happily married woman and now mother, Tai's life couldn't be more complete. But she starts to suspect that someone is stalking her, or is her mind playing tricks on her? Tai recruits her intuitive sidekick, Nevada, a successful Washington, D.C, but even the seasoned sleuth is in for a shock when she discovers who the culprit is. Meanwhile, fashionista Candace has been enjoying her long engagement, but something is amiss and she can't figure out what's keeping him from taking the plunge. So just like Tai, she decides to call on Nevada's good instincts.

In spite of the enticing promises of the post-genomic era, the pharmaceutical world is in a state of disarray. Drug discovery seems now riskier and more uncertain than ever. Thus, projects get routinely terminated in mid-stage clinical trials, new targets are getting harder to find, and successful therapeutic agents are often recalled as unanticipated side effects are discovered. Exploiting the huge output of genomic studies to make safer drugs has proven to be much more difficult than anticipated. More than ever, the lead in the pharmaceutical industry depends on the ability to harness innovative research, and this type of innovation can only come from one source: fundamental knowledge. This book squarely addresses this crucial problem since it introduces fundamental discoveries in basic biomolecular research that hold potential to broaden the technological base of the pharmaceutical industry. The book takes a fresh and fundamental look at the problem of how to design an effective drug with controlled specificity. Since the novel transformative concepts are unfamiliar to most practitioners, the first part of this book explains matters very carefully starting from a fairly elementary physico-chemical level. The second part of the book is devoted to practical applications, aiming at nothing less than a paradigm shift in drug design. This book is addressed to scientists working at the cutting edge of research in the pharmaceutical industry, but the material is at the same time accessible to senior undergraduates or graduate students interested in drug discovery and molecular design.

Protected cropping shelters crops from extreme climatic conditions by modifying the internal growing conditions in their favor. The technology has widely been used for vegetable crops in different climates such as temperate, tropical, subtropical, arid, and semi-arid regions. As climate change is projected to become more severe in the near future, the resulting adverse weather conditions such as higher temperatures, more frequent heatwaves, more variable rainfall patterns, and cyclones will affect vegetable production, in turn affecting crop growth, yield, produce quality, and economic return of growers. The demand for protected cultivation will increase to ensure sustainable production and a stable supply of fresh horticultural produce.

This book explores quantitative aspects of protein biophysics and attempts to delineate certain rules of molecular behavior that make atomic scale objects behave in a digital way. This book will help readers to understand how certain biological systems involving proteins function as digital information systems despite the fact that underlying processes are analog in nature. The in-depth explanation of proteins from a quantitative point of view and the variety of level of exercises (including physical experiments) at the end of each chapter will appeal to graduate and senior undergraduate students in mathematics, computer science, mechanical engineering, and physics, wanting to learn about the biophysics of proteins. L. Ridgway Scott has been Professor of Computer Science and of Mathematics at the University of Chicago since 1998, and the Louis Block Professor since 2001. He obtained a B.S. degree (Magna Cum Laude) from Tulane University in 1969 and a PhD degree in Mathematics from the Massachusetts Institute of Technology in 1973. Professor Scott has published over 130 papers and three books, extending over biophysics, parallel computing and fundamental computing aspects of structural mechanics, fluid dynamics, nuclear engineering, and computational chemistry. Ariel Fernández (born Ariel Fernández Stigliano) is an Argentinian-American physical chemist and mathematician. He obtained his Ph. D. degree in Chemical Physics from Yale University and held the Karl F. Hasselmann Endowed Chair Professorship in Bioengineering at Rice University. He is currently involved in research and entrepreneurial activities at various consultancy firms. Ariel Fernández authored three books on translational medicine and biophysics, and published 360 papers in professional journals. He holds two patents in the field of biotechnology.

Vols. for 1904-1926 include also decisions of the United States Board of General Appraisers.

Consumption of fresh fruits and vegetables has increased dramatically in the last several decades. This increased consumption has put a greater burden on the fresh produce industry to provide fresher product quality, combined with a high level of food safety. Therefore, postharvest handling, storage and shipment of horticultural crops, including fruit and vegetable products has increased in importance. Novel Postharvest Treatments of Fresh Produce focuses mainly on the application of novel treatments for fruits and vegetables shipping and handling life. A greater emphasis is placed on effects of postharvest treatments on senescence and ripening, bioactive molecule contents and food safety. The work presented within this book explores a wide range of topics pertaining to novel postharvest treatments for fresh and fresh-cut fruits and vegetables including applications of various active agents, green postharvest treatments, physical treatments and combinations of the aforementioned.

Wind, wrap, and sew fabric strips into fantastic containers! Start with a plate shape to learn the technique. Then experiment with four basic container styles to create round, oval, square, and other shapes. Create purses, baskets, and bowls in an endless variety of sizes, shapes, and colors Simply wrap fabric strips around cotton clothesline, coil into the desired shape, and secure with machine stitching Special sections on lids, handles, and embellishments offer unlimited options for your own variations