Zika Virus Impact, Diagnosis, Control, and Models: Volume Two: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions. Provides a broad range of topics related to the neuroscience of Zika, including its diagnosis, vaccines and therapy Contains chapter abstracts, key facts, a dictionary of terms and summary points to aid in understanding Discusses novel and non-pharmacological therapies, Guillain-Barré Syndrome and vaccine development Features chapters on rat, mouse, and guinea pig models of Zika and case reports of Zika co-infection with chikungunya, dengue-2 and Guillain-Barré Includes coverage of microcephaly and developmental delays and examines Zika outbreaks in Brazil, Honduras, Uganda, Jamaica and Mozambique

Zika Virus Biology, Transmission, and Pathology: The Neuroscience of Zika provides a detailed introduction to the molecular biology of the Zika virus and its features, transmission, and impact on neurological systems. Designed to better readers' understanding of the Zika virus, this volume features chapters on the immune response, molecular mechanisms, and other areas to better understand underlying pathways. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions. Zika Virus Impact, Diagnosis, Control, and Models: The Neuroscience of Zika examines diagnosis, vaccines, and potential therapy methods for Zika virus syndrome. The book also details the neuroscience of Guillain-Barré syndrome, its effects and neuromuscular rehabilitation. It is designed to help readers better understand detection, therapies for Zika virus, preventative vaccines, diagnosis and associated microcephaly. Chapters on models enable further research and understanding. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions.Zika Virus Biology, Transmission, and Pathology: - Presents the most comprehensive coverage of a broad range of topics related to the neuroscience of Zika, including transmission and virus biology - Contains an abstract, key facts, a mini dictionary of terms, and summary points to aid in understanding in each chapter - Features chapters on Zika vectors and fetal imaging - Includes coverage of microcephaly and developmental delays and examines Zika outbreaks in Brazil, Puerto Rico and India - Discusses unique topics in Zika biology, associated neuro-inflammation, and impacts on neurological systems Zika Virus Impact, Diagnosis, Control, and Models: - Provides a broad range of topics related to the neuroscience of Zika, including its diagnosis, vaccines and therapy - Contains chapter abstracts, key facts, a dictionary of terms and summary points to aid in understanding - Discusses novel and non-pharmacological therapies, Guillain-Barré Syndrome and vaccine development - Features chapters on rat, mouse, and guinea pig models of Zika and case reports of Zika co-infection with chikungunya, dengue-2 and Guillain-Barré - Includes coverage of microcephaly and developmental delays and examines Zika outbreaks in Brazil, Honduras, Uganda, Jamaica and Mozambique

Zika Virus Biology, Transmission, and Pathways: The Neuroscience of Zika, Volume One provides a detailed introduction to the molecular biology of the Zika virus and its features, transmission, and impact on neurological systems. Designed to better readers' understanding of the Zika virus, this volume features chapters on the immune response, molecular mechanisms, and other areas to better understand underlying pathways. This book has applicability for neuroscientists, neurologists, virologists and anyone working to better understand the evolution and pathogenesis of Zika virus-related conditions. - Presents the most comprehensive coverage of a broad range of topics related to the neuroscience of Zika, including transmission and virus biology - Contains an abstract, key facts, a mini dictionary of terms, and summary points to aid in understanding in each chapter - Features chapters on Zika vectors and fetal imaging - Includes coverage of microcephaly and developmental delays and examines Zika outbreaks in Brazil, Puerto Rico and India - Discusses unique topics in Zika biology, associated neuro-inflammation, and impacts on neurological systems

This handbook provides a detailed overview of the emotional, physical, and social implications of anger, aggression, and violence. The book covers the recognition, diagnosis, and evaluation of these areas, aiming to understand the aetiology of these behavioral features to assist with prevention and cure. The book is divided into eight sections: Placing Aggression, Anger, Aggression and Violence In Context Causes and Precipitation of Anger, Aggression and Violence Features of Anger, Aggression and Violence Anger, Aggression and Violence in Defined Disorders and Conditions Physical Measures of Pathology and Insights: Genetics Physical Measures of Pathology and Insights: Non-Genetic Treatments and Therapies Methods and Techniques Handbook of Anger, Aggression, and Violence will be of use for behavioral scientists, psychologists, psychiatric nurses and doctors, neurologists, health scientists, general practitioners, research scientists and all those interested in altered behavior.

The book provides an introduction to deterministic (and some stochastic) modeling of spatiotemporal phenomena in ecology, epidemiology, and neural systems. A survey of the classical models in the fields with up to date applications is given. The book begins with detailed description of how spatial dynamics/diffusive processes influence the dynamics of biological populations. These processes play a key role in understanding the outbreak and spread of pandemics which help us in designing the control strategies from the public health perspective. A brief discussion on the functional mechanism of the brain (single neuron models and network level) with classical models of neuronal dynamics in space and time is given. Relevant phenomena and existing modeling approaches in ecology, epidemiology and neuroscience are introduced, which provide examples of pattern formation in these models. The analysis of patterns enables us to study the dynamics of macroscopic and microscopic behaviour of underlying systems and travelling wave type patterns observed in dispersive systems. Moving on to virus dynamics, authors present a detailed analysis of different types models of infectious diseases including two models for influenza, five models for Ebola virus and seven models for Zika virus with diffusion and time delay. A Chapter is devoted for the study of Brain Dynamics (Neural systems in space and time). Significant advances made in modeling the reaction-diffusion systems are presented and spatiotemporal patterning in the systems is reviewed. Development of appropriate mathematical models and detailed analysis (such as linear stability, weakly nonlinear analysis, bifurcation analysis, control theory, numerical simulation) are presented. Key Features Covers the fundamental concepts and mathematical skills required to analyse reaction-diffusion models for biological populations. Concepts are introduced in such a way that readers with a basic knowledge of differential equations and numerical methods can understand the analysis. The results are also illustrated with figures. Focuses on mathematical modeling and numerical simulations using basic conceptual and classic models of population dynamics, Virus and Brain dynamics. Covers wide range of models using spatial and non-spatial approaches. Covers single, two and multispecies reaction-diffusion models from ecology and models from bio-chemistry. Models are analysed for stability of equilibrium points, Turing instability, Hopf bifurcation and pattern formations. Uses Mathematica for problem solving and MATLAB for pattern formations. Contains solved Examples and Problems in Exercises. The Book is suitable for advanced undergraduate, graduate and research students. For those who are working in the above areas, it provides information from most of the recent works. The text presents all the fundamental concepts and mathematical skills needed to build models and perform analyses.

The considerable number of viral infectious disease threats that have emerged since the beginning of the 21st century have shown the need to dispose global and coordinated responses to fight properly and efficiently against them. Severe acute respiratory syndrome (2003), avian influenza in humans (2005), A(H1N1) pandemic influenza (2009), Middle East respiratory syndrome coronavirus (MERS-CoV) (2012 onward) and Ebola virus disease (2014-2015) are some of the most important examples. The latest emerging and devastating threat was Zika virus, an arbovirus that provoked more than 500,000 suspicious cases in the Americas in 2016 and notable processes of social and medical alarms due to the evidence of a causal link between Zika virus and several congenital injuries, like microcephaly, as well as due to its association with neurological disorders such as Guillain-Barré syndrome in adults (PAHO, 2017). In the framework of this global response and multistrategic approach, the purpose of this Research Topic is to provide updated information and novel researches about control strategies, encompassing virological, entomological and epidemiological data, in order to reach the triad of protagonists of transmission cycles (virus, mosquitoes and humans).

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of infectious diseases, including novel infections and lesser-known microorganisms, this volume incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Infectious Diseases is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. - Covers all areas of infectious disease pathology, including infections of the central nervous system, head and neck, and skin/soft tissue as well as the pulmonary, cardiac, gastrointestinal, genitourinary, and gynecologic systems - Includes new chapters on COVID-19 and mpox, nine new helminth chapters, additional new fungal chapters, an updated biosafety chapter, and more - Contains significantly updated information throughout, including new content on artificial intelligence, whole-slide and mass spectrometry imaging, and metagenomic next-generation sequencing - Discusses the best approach for diagnostic work-up and addresses the challenges in maximizing diagnostic yield while avoiding misinterpretation of results that could lead to false positives - Details the increasing use of molecular diagnostics in infectious disease pathology - Provides updates on taxonomy and nomenclature across all classes of infectious microorganisms (bacteria, fungi, parasites, viruses) along with new genomic data - Features more than 1,500 print and online-only images, including histology and gross pathology images, full-color medical illustrations, clinical photographs, and radiology images to help practicing and in-training pathologists reach a confident diagnosis - Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care - Any additional digital ancillary content may publish up to 6 weeks following the publication date

Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us. Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life. - Provides insight to newer and futuristic technologies to understand disease process and drug design by animal models - Addresses a wide variety of species and covers a wide variety of topics (such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations) to fully prepare for work with all types of animals - Gives a perspective on laboratory animal use that allows to explain the benefits of animal use as required by veterinary technology program accreditation procedure - Includes examples of animal bio-technological techniques (including stem cell and tissue engineering) for their applications to humanity - Offers new insight into ways of enhancing animal welfare by the inclusion of research results focused on immunology and laboratory animal behavior