Increasing interest in the development and validation of quantitative imaging biomarkers for oncologic imaging has in recent years inspired a surge in the field of artificial intelligence and machine learning. Initial results showed promise in identifying potential markers of treatment response, malignant potential, and prognostic predictors, among others; however, while many of these early algorithms showed the optimistic ability to separate pathologic states on “in-house” datasets, it was often the case that these classifiers generalized poorly on external validation sets and thus were of limited utility in the clinical setting. This issue was additionally compounded by the frequent use of data filtering and feature selection techniques in many studies to further bolster the machine learning results in limited case scenarios, thereby biasing the overall fit and further reducing generalizability.

Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

ARTIFICIAL INTELLIGENCE FOR BONE DISORDER The authors have produced an invaluable resource that connects the fields of AI and bone treatment by providing essential insights into the current state and future of AI in bone condition diagnosis and therapy, as well as a methodical examination of machine learning algorithms, deep learning approaches, and their real-world uses. The book explores the use of artificial intelligence (AI) in the diagnosis and treatment of various bone illnesses. The integration of AI approaches in the fields of orthopedics, radiography, tissue engineering, and other areas related to bone are discussed in detail. It covers tissue engineering methods for bone regeneration and investigates the use of AI tools in this area, emphasizing the value of deep learning and how to use AI in tissue engineering efficiently. The book also covers diagnostic and prognostic uses of AI in orthopedics, such as the diagnosis of disorders involving the hip and knee as well as prognoses for therapies. Chapters also look at MRI, trabecular biomechanical strength, and other methods for diagnosing osteoporosis. Other issues the book examines include several uses of AI in pediatric orthopedics, 3D modeling, digital X-ray radiogrammetry, convolutional neural networks for customized care, and digital tomography. With information on the most recent developments and potential future applications, each chapter of the book advances our understanding of how AI might be used to diagnose and treat bone problems. Audience This book will serve as a guide for orthopedic experts, biomedical engineers, faculty members, research scholars, IT specialists, healthcare workers, and hospital administrators.

This book aims to compile an expert text on the multidisciplinary approach to treating sarcoma at a sarcoma centre. Separate chapters and sections highlight the specialist diagnostic and therapeutic approaches employed in treating bone and soft tissue sarcoma. This comprehensive book covers sarcoma and its management across specialties. It brings together the experience of the editor at a major centre for sarcoma management in Australia along with chapter contributions from various experts on the topic. The real-life, pragmatic approach is a distillation of the evidence and intends to make much of what is written translatable. This book serves as a reference for managing this tumour type and as an indispensable guide for daily use across the spectrum of providers.

Advances in Clinical Radiology was established to review the year’s most important questions in clinical radiology. A distinguished editorial board, headed by Dr. Frank Miller, identifies key areas of major progress and controversy, and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in radiology bring concepts to a clinical level and explore their everday impact on patient care.

This book presents artificial intelligence applications that may help in detecting disease, defining tissue characterization (benign vs malignant), staging and correlation with molecular biomarkers. Originally positioned as a means for noninvasive molecular phenotyping and quantification in the 1970s, PET's technological improvements in the 2000s generated renewed interest in quantification, which has grown over the last five years. This progress is parallel with the development of Artificial intelligence (AI) systems for Oncology which aim at providing the best possible treatment to patients suffering from lung, breast, brain, prostate, liver and other types of cancer. The chapters provide an overview of the use of AI in PET/CT imaging for various types of cancer, and it will be an invaluable tool especially for nuclear medicine physicians and oncologists.

The most common form of severe dementia, Alzheimer’s disease (AD), is a cumulative neurological disorder because of the degradation and death of nerve cells in the brain tissue, intelligence steadily declines and most of its activities are compromised in AD. Before diving into the level of AD diagnosis, it is essential to highlight the fundamental differences between conventional machine learning (ML) and deep learning (DL). This work covers a number of photo-preprocessing approaches that aid in learning because image processing is essential for the diagnosis of AD. The most crucial kind of neural network for computer vision used in medical image processing is called a Convolutional Neural Network (CNN). The proposed study will consider facial characteristics, including expressions and eye movements using the diffusion model, as part of CNN’s meticulous approach to Alzheimer’s diagnosis. Convolutional neural networks were used in an effort to sense Alzheimer’s disease in its early stages using a big collection of pictures of facial expressions.