A textbook for students with limited background in mathematics and computer coding, emphasizing computer tutorials that guide readers in producing models of neural behavior. This introductory text teaches students to understand, simulate, and analyze the complex behaviors of individual neurons and brain circuits. It is built around computer tutorials that guide students in producing models of neural behavior, with the associated Matlab code freely available online. From these models students learn how individual neurons function and how, when connected, neurons cooperate in a circuit. The book demonstrates through simulated models how oscillations, multistability, post-stimulus rebounds, and chaos can arise within either single neurons or circuits, and it explores their roles in the brain. The book first presents essential background in neuroscience, physics, mathematics, and Matlab, with explanations illustrated by many example problems. Subsequent chapters cover the neuron and spike production; single spike trains and the underlying cognitive processes; conductance-based models; the simulation of synaptic connections; firing-rate models of large-scale circuit operation; dynamical systems and their components; synaptic plasticity; and techniques for analysis of neuron population datasets, including principal components analysis, hidden Markov modeling, and Bayesian decoding. Accessible to undergraduates in life sciences with limited background in mathematics and computer coding, the book can be used in a “flipped” or “inverted” teaching approach, with class time devoted to hands-on work on the computer tutorials. It can also be a resource for graduate students in the life sciences who wish to gain computing skills and a deeper knowledge of neural function and neural circuits.

This book addresses the growing need for machine learning and data mining in neuroscience. The book offers a basic overview of the neuroscience, machine learning and the required math and programming necessary to develop reliable working models. The material is presented in a easy to follow user-friendly manner and is replete with fully working machine learning code. Machine Learning for Neuroscience: A Systematic Approach, tackles the needs of neuroscience researchers and practitioners that have very little training relevant to machine learning. The first section of the book provides an overview of necessary topics in order to delve into machine learning, including basic linear algebra and Python programming. The second section provides an overview of neuroscience and is directed to the computer science oriented readers. The section covers neuroanatomy and physiology, cellular neuroscience, neurological disorders and computational neuroscience. The third section of the book then delves into how to apply machine learning and data mining to neuroscience and provides coverage of artificial neural networks (ANN), clustering, and anomaly detection. The book contains fully working code examples with downloadable working code. It also contains lab assignments and quizzes, making it appropriate for use as a textbook. The primary audience is neuroscience researchers who need to delve into machine learning, programmers assigned neuroscience related machine learning projects and students studying methods in computational neuroscience.

A comprehensive, integrated, and accessible textbook presenting core neuroscientific topics from a computational perspective, tracing a path from cells and circuits to behavior and cognition. This textbook presents a wide range of subjects in neuroscience from a computational perspective. It offers a comprehensive, integrated introduction to core topics, using computational tools to trace a path from neurons and circuits to behavior and cognition. Moreover, the chapters show how computational neuroscience—methods for modeling the causal interactions underlying neural systems—complements empirical research in advancing the understanding of brain and behavior. The chapters—all by leaders in the field, and carefully integrated by the editors—cover such subjects as action and motor control; neuroplasticity, neuromodulation, and reinforcement learning; vision; and language—the core of human cognition. The book can be used for advanced undergraduate or graduate level courses. It presents all necessary background in neuroscience beyond basic facts about neurons and synapses and general ideas about the structure and function of the human brain. Students should be familiar with differential equations and probability theory, and be able to pick up the basics of programming in MATLAB and/or Python. Slides, exercises, and other ancillary materials are freely available online, and many of the models described in the chapters are documented in the brain operation database, BODB (which is also described in a book chapter). Contributors Michael A. Arbib, Joseph Ayers, James Bednar, Andrej Bicanski, James J. Bonaiuto, Nicolas Brunel, Jean-Marie Cabelguen, Carmen Canavier, Angelo Cangelosi, Richard P. Cooper, Carlos R. Cortes, Nathaniel Daw, Paul Dean, Peter Ford Dominey, Pierre Enel, Jean-Marc Fellous, Stefano Fusi, Wulfram Gerstner, Frank Grasso, Jacqueline A. Griego, Ziad M. Hafed, Michael E. Hasselmo, Auke Ijspeert, Stephanie Jones, Daniel Kersten, Jeremie Knuesel, Owen Lewis, William W. Lytton, Tomaso Poggio, John Porrill, Tony J. Prescott, John Rinzel, Edmund Rolls, Jonathan Rubin, Nicolas Schweighofer, Mohamed A. Sherif, Malle A. Tagamets, Paul F. M. J. Verschure, Nathan Vierling-Claasen, Xiao-Jing Wang, Christopher Williams, Ransom Winder, Alan L. Yuille

When funding agencies and policy organizations consider the role of modeling and simulation in modern biology, the question is often posed, what has been accomplished ? This book will be organized around a symposium on the 20 year history of the CNS meetings, to be held as part of CNS 2010 in San Antonio Texas in July 2010. The book, like the symposium is intended to summarize progress made in Computational Neuroscience over the last 20 years while also considering current challenges in the field. As described in the table of contents, the chapter’s authors have been selected to provide wide coverage of the applications of computational techniques to a broad range of questions and model systems in neuroscience. The proposed book will include several features that establish the history of the field. For each article, its author will select an article originally appearing in a CNS conference proceedings from 15 – 20 years ago. These short (less than 6 page) articles will provide illustrations of the state of the field 20 years ago. The new articles will describe what has been learned about the subject in the following 20 years, and pose specific challenges for the next 20 years. The second historical mechanism will be the reproduction of the first 12 years of posters from the CNS meeting. These posters in and of themselves have become famous in the field (they hang in the halls of the NIH in Bethesda Maryland) and were constructed as allegories for the state and development of computational neuroscience. The posters were designed by the book’s editor, who will, for the first time, provide a written description of each poster.

The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. Completely redesigned and revised, it introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain.

Computational Neuroscience - A First Course provides an essential introduction to computational neuroscience and equips readers with a fundamental understanding of modeling the nervous system at the membrane, cellular, and network level. The book, which grew out of a lecture series held regularly for more than ten years to graduate students in neuroscience with backgrounds in biology, psychology and medicine, takes its readers on a journey through three fundamental domains of computational neuroscience: membrane biophysics, systems theory and artificial neural networks. The required mathematical concepts are kept as intuitive and simple as possible throughout the book, making it fully accessible to readers who are less familiar with mathematics. Overall, Computational Neuroscience - A First Course represents an essential reference guide for all neuroscientists who use computational methods in their daily work, as well as for any theoretical scientist approaching the field of computational neuroscience.

Dive into the cutting-edge world of Neuromorphic Computing, a groundbreaking volume that unravels the secrets of brain-inspired computational paradigms. Spanning neuroscience, artificial intelligence, and hardware design, this book presents a comprehensive exploration of neuromorphic systems, empowering both experts and newcomers to embrace the limitless potential of brain-inspired computing. Discover the fundamental principles that underpin neural computation as we journey through the origins of neuromorphic architectures, meticulously crafted to mimic the brain’s intricate neural networks. Unlock the true essence of learning mechanisms – unsupervised, supervised, and reinforcement learning – and witness how these innovations are shaping the future of artificial intelligence.

DCAI 2022 is a forum to present applications of innovative techniques for studying and solving complex problems in artificial intelligence and computing areas. The present edition brings together past experience, current work and promising future trends associated with distributed computing, artificial intelligence and their application in order to provide efficient solutions to real problems. This year’s technical program will present both high quality and diversity, with contributions in well-established and evolving areas of research. Specifically, 61 papers were submitted, by authors from 28 different countries representing a truly “wide area network” of research activity. The DCAI’22 technical program has selected 32 full papers and, as in past editions, it will be special issues in ranked journals. This symposium is organized by the University of L'Aquila (Italy). We would like to thank all the contributing authors, the members of the Program Committee and the sponsors (IBM, Indra, Dipartimento di Ingegneria e Scienze dell'Informazione e Matematica dell'Università degli Studi dell'Aquila, Armundia Group, Whitehall Reply, T.C. Technologies And Comunication S.R.L., LCL Industria Grafica, AIR Institute, AEPIA, APPIA).

An accessible undergraduate textbook in computational neuroscience that provides an introduction to the mathematical and computational modeling of neurons and networks of neurons. Understanding the brain is a major frontier of modern science. Given the complexity of neural circuits, advancing that understanding requires mathematical and computational approaches. This accessible undergraduate textbook in computational neuroscience provides an introduction to the mathematical and computational modeling of neurons and networks of neurons. Starting with the biophysics of single neurons, Robert Rosenbaum incrementally builds to explanations of neural coding, learning, and the relationship between biological and artificial neural networks. Examples with real neural data demonstrate how computational models can be used to understand phenomena observed in neural recordings. Based on years of classroom experience, the material has been carefully streamlined to provide all the content needed to build a foundation for modeling neural circuits in a one-semester course. Proven in the classroom Example-rich, student-friendly approach Includes Python code and a mathematical appendix reviewing the requisite background in calculus, linear algebra, and probability Ideal for engineering, science, and mathematics majors and for self-study

Presents biophysical theory and computer code for modelling and interpreting extracellular electric and magnetic brain signals.