With their advantages of controlled delivery and modular flexibility, biomaterials have fundamentally revolutionized disease diagnosis and therapy. Bioactive nanomaterials are not simple miniaturizations of macroscopic materials. They exhibit unique and intrinsic bioactivities as they readily acquire a precise structure upon interaction with the biological environment. Nowadays, bioactive materials offer great potential in eliciting specific responses and regulations of living tissues for diagnostics, therapeutics, and regenerative medicine. We are optimistic that the increasing innovations and advances in bioactive and biomimetic materials with sophisticated bioactivities and controllable responsiveness will make an important contribution to the next generation of biomaterials and biomedical engineering.

This book begins with an introduction of nanobiotechnology, followed by biosyntheses of AgNPs, development of silver/chitosan (Ag/CS) polymer nanocomposites, synthesis of silver/chitosan-g-poly acrylamide (Ag/CS-g-PAAm) nanocomposite hydrogel and silver/chitosan/poly vinyl chloride (Ag/CS/PVC) blend. Finally, it presents novel bioengineering of polyfunctional metallic nanostructures other than Ag, emphasizing biomass utilization and value-added conversion over an extended span, including life cycle assessment of the synthesized nanostructures. Features: Includes prospective cost effective, eco-friendly, and safe nanomaterials, synthesized through facile paths Covers the synergistic effect of phytochemicals and nano-Ag antimicrobial agents from an antiviral perspective Includes surface coating systems and super absorbent materials for biomedical purposes Examines nanobiotechnological applications for generating nanoalloys with synchronized nanostructural arrangement of alkaline earth metals and nanoscale dots of transition metals Explores the life cycle assessment of synthesized nanomaterials This book aims at researchers and graduate students in biomaterials, chemical engineering, green chemistry, nanomaterials, and biotechnology.

New Trends in Smart Nanostructured Biomaterials in Health Sciences provides guidance on the design and synthesis of nanostructured smart biomaterials, as well as the resultant therapeutic effects and associated biomedical applications of these novel materials. The book provides readers with a deeper understanding of these novel biomaterials and aids them in making informed decisions when selecting appropriate materials for tissue engineering and cancer therapy applications. It will be of specific interest to materials scientists, biomedical engineers, oncological scientists, tissue engineers and those working in regenerative medicine. Nanostructured smart materials have the special ability to respond to changes in the cell microenvironment, allowing for robust, biocompatible and rapidly adaptable, therapeutic and restorative action against a range of ailments. These materials are thus ideal candidates for use in tissue engineering and cancer therapy due to the varying nature of the cell microenvironment between persons, tissues and cancers. This book covers the design, synthesis, unique properties and application of smart biomaterials in these two key topic areas of tissue engineering and cancer therapeutics. - Presents an overview of how smart biomaterials respond to changes in physiological factors and exogeneous stimuli and their impact in modern medicine - Provides readers with the basis for designing, processing and characterizing advanced smart biomaterials - Guides the reader through the mechanisms of tissue repair and cancer therapeutics by exploring the most relevant features of smart nanostructured materials

Computational Approaches in Bioengineering, Volume 2—Computational Approaches in Biomaterials and Biomedical Engineering Applications is a comprehensive and up-to-date resource that provides a broad overview of the use of computational methods in the fields of biomaterials and biomedical engineering. Written by a team of experts in the field of biomaterials and biomedical engineering, it provides a wealth of information on the use of computational methods in these fields. Furthermore, it explores emerging trends and discusses future directions and associated limitations in the field. Through thorough exploration and explanation, it showcases the latest research and advancements, offering valuable insights into how computational methods are utilized to design and optimize biomaterials, simulate biological processes, and develop innovative medical devices. FEATURES Provides practical guidance and real-world examples to help readers apply computational approaches effectively in their work Explores the diverse computational approaches employed in biomaterials and biomedical engineering applications, offering a comprehensive view of the field Introduces emerging topics and cutting-edge techniques, keeping wide range of readers at the forefront of advancements in computational bioengineering Discusses the integration of computational methods in biomaterials and biomedical engineering, fostering a deeper understanding of their synergistic potential Provides a valuable resource for researchers, practitioners, and students alike, serving as a comprehensive guide to computational approaches in biomaterials and biomedical engineering applications The book is well-organized and easy to read. The chapters are written in a clear and concise style, and they provide a comprehensive overview of the topics covered. The book is also well-illustrated with figures and tables that help to explain the concepts discussed in the text. With its comprehensive coverage, practical examples, and expert insights, this book serves as a valuable resource for researchers, students, and professionals in the fields of biomaterials and biomedical engineering.

Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical practice. The book begins with an emphasis on the latest research in the pathogenesis of BAI from microbiological, immunological, and materials science perspectives. The current state of the art in antimicrobial activation of biomaterials through surface modification and the incorporation of antimicrobial agents is then discussed. In the concluding chapters, successful translation of a selection of antimicrobial technologies from preclinical research into clinical use is described alongside a discussion of the utility of these devices and perspectives for future development. This book is essential reading for researchers and clinicians who are interested in understanding the fundamentals of BAI, the latest in antimicrobial materials research, and the state of the art in clinically available antimicrobial containing medical devices.