The first issue of Clinics in Chest Medicine to be published with this focus, this issue reviews bronchiectasis from numerous angles to provide comprehensive coverage on this important subject. Epidemiology, airway defense mechanisms, pathogenesis, imaging and genetic causes of bronchiectasis are discussed. Allergic bronchopulmonary aspergillosis is addressed, as well as non-tuberculous mycobacteria as a cause of bronchiectasis. Authors examine how to evaluate the success of therapy for bronchiectasis (what endpoints to use) and then discuss a variety of therapy options: inhaled and systemic antibiotic treatment, chest physiotherapy, pharmacologic agents for mucous clearance, antipinflammatory therapy and macrolides. Pulmonary resection and lung transplantation for bronchiectasis are reviewed. Recent advances in Cystic Fibrosis are also discussed.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

In this issue of Clinics in Chest Medicine, Guest Editors Harold R Collard, Luca Richeldi, and Kerri A. Johannson bring their considerable expertise to the topic of Next-generation Interstitial Lung Disease. Provides concise and comprehensive coverage of the issues physicians face every day. Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field.

The guest editors for this issue, Talmadge King, Harold Collard, celebrated pulmonary specialists from UCSF, and Luca Richeldi, renowned visiting professor to UCSF from University of Modena, Italy, bring together a state-of-the-art issue on the important topic of Interstitial Lung Diseases (ILD). This comprehensive issue reviews the approach to diagnosis of ILD, radiology if ILD, pathology of ILD. Idiopathic pulmonary fibrosis is discussed, including phenotypes and comorbidities, acute exacerbation and accelerated decline, management, and pathobiology of novel approaches to therapy. Connective Tissue ILD, Chronic Hypersensitivity Pneumonitis, familial ILD and smoking-related ILD, and non-specific interstitial pneumonia are reviewed. In the final article, lung transplantation is discussed.

Dr. Jon Koff has assembled and expert team of authors of the topic of Cystic Fibrosis. Articles include: Epidemiology and Pathobiology, Genetics and genetic medicine in Cystic Fibrosis, Innate and Adaptive Immunity in Cystic Fibrosis, Microbiome in Cystic Fibrosis, Diagnostic Testing in Cystic Fibrosis, Treating Pseudomonas in Cystic Fibrosis, Diagnosis of Adult Patients with Cystic Fibrosis, Transition from Pediatrics to Adult Care, Lung Transplant in Cystic Fibrosis, and more!

In this issue of Clinics in Chest Medicine, guest editors Drs. Shannon Kasperbauer and Rachel Thomson bring their considerable expertise to the topic of Nontuberculous Mycobacterial Pulmonary Disease. Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a challenging infection which is becoming increasingly prevalent, particularly in the elderly, for reasons which are unknown. In this issue, top experts discuss topics such as environmental sources and transmission of nontuberculous mycobacteria; global epidemiology; host susceptibility; investigation and management of bronchiectasis in nontuberculous mycobacterial pulmonary disease; and more. - Contains 15 practice-oriented topics including novel antimicrobial agents in nontuberculous pulmonary disease; host directed therapy in nontuberculous pulmonary disease; cystic fibrosis related nontuberculous mycobacterial pulmonary disease; surgical resection in nontuberculous mycobacterial pulmonary disease; and more. - Provides in-depth clinical reviews on nontuberculous mycobacterial pulmonary disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Chest Medicine, guest editor Dr. Jane P. Ko brings her considerable expertise to the topic of Thoracic Imaging. Top experts discuss CT signs in the lungs; pericardial recesses on CT: implications for the pulmonologist; imaging of solid pulmonary nodules; subsolid nodules: significance and current understanding; ICU imaging pearls and pitfalls; and more. - Contains 20 relevant, practice-oriented topics including imaging the patient with COVID-19: acute to long COVID; CTEPH: clinical and imaging evaluation; update on interstitial pneumonias; ILAs: current understanding; imaging of lung transplantation; imaging of the large airways; and more. - Provides in-depth clinical reviews on thoracic imaging, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Drs. Huitt and Daley have assembled an expert panel of authors on the topic of Non-Tuberculosis Mycobacteria. Articles in this issue will include discussions in the following areas: The Pathogenesis of NTM, Epidemiology of NTM, Environmental Sources of NTM, Laboratory Diagnosis of NTM, Medications and Monitoring in NTM infections, Treatment of Rapidly Growing NTM, Treatment of Slow Growing NTM, NTM Infections in Immunocompromised Hosts, Extra Pulmonary NTM Infections, NTM Infections in Cystic Fibrosis, and Surgical Approach to NTM Infections.

Drs. Robert Kotloff and Francis McCormack have assembled an expert team of authors on the topic of Rare and Orphan Lung Diseases. Articles include: Lymphangioleiomyomatosis, Pulmonary Lymphangiomatosis, Langerhans Cell Histiocytosis and other Histiocytic Diseases of the Lung, Pulmonary Alveolar Proteinosis, Pulmonary Alveolar Microlithiasis, Primary Ciliary Dyskinesia, Birt-Hogg-Dube Syndrome, Hermansky-Pudlak Syndrome, Hereditary Hemorrhagic Telangiectasia, Non-CF Bronchiectasis, Eosinophilic Lung Diseases, Benign Metastasizing Leiomyomata, and more!

In this issue of Clinics in Chest Medicine, guest editors Drs. Luis Angel and Stephanie M. Levine bring their considerable expertise to the topic of Lung Transplantation. Top experts in the field cover key topics such as difficult decisions to transplant patients who are older, frail, underweight and obese; organ donation and variability in conversion to lung transplantation; conventional and novel approaches to immunosuppression; acute rejection and chronic allograft dysfunction; and more. - Contains 14 relevant, practice-oriented topics including COVID-19 and lung transplantation; the lung transplant candidate: indications, timing and selection criteria; bilateral lung transplantation vs. single lung transplant: complications, quality of life, and survival; critical care management of the lung transplant recipient; and more. - Provides in-depth clinical reviews on lung transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.