Dr. Jon Koff has assembled and expert team of authors of the topic of Cystic Fibrosis. Articles include: Epidemiology and Pathobiology, Genetics and genetic medicine in Cystic Fibrosis, Innate and Adaptive Immunity in Cystic Fibrosis, Microbiome in Cystic Fibrosis, Diagnostic Testing in Cystic Fibrosis, Treating Pseudomonas in Cystic Fibrosis, Diagnosis of Adult Patients with Cystic Fibrosis, Transition from Pediatrics to Adult Care, Lung Transplant in Cystic Fibrosis, and more!

In this issue of Clinics in Chest Medicine, guest editors Drs. Clemente J. Britto and Jennifer L. Taylor-Cousar bring their considerable expertise to Advances in Cystic Fibrosis. Top experts in the field cover key topics such as genetics of cystic fibrosis (CF): clinical implications; innate and adaptive immunity in CF; novel applications of biomarkers and personalized medicine to define the spectrum of CF; emerging approaches to understand CF pathogenesis; and more. - Contains 18 relevant, practice-oriented topics including novel approaches to multidrug resistant infections in CF; clinical outcomes of highly-effective modulator therapy; nontuberculous mycobacterial infections in CF; management of mental health in CF; sexual and reproductive health in CF; nutritional management in CF; transitions of care in CF; and more. - Provides in-depth clinical reviews on advances in cystic fibrosis, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Clinics in Chest Medicine, guest-edited by Dr. Margaret Pisani, is focused on Gender and Respiratory Disease. Topics discussed in this issue include but are not limited to: What are sex and gender and how can we study their impact in respiratory disease?, Sex differences in respiratory physiology, Impact of gender on social determinants of health, Gender differences in obstructive sleep apnea, Impact of gender on sleep disorders across the lifespan, Differences between men and women with COPD, Women and Lung Cancer, Pulmonary considerations in pregnant women and Asthma in women-gender specific considerations.

The first issue of Clinics in Chest Medicine to be published with this focus, this issue reviews bronchiectasis from numerous angles to provide comprehensive coverage on this important subject. Epidemiology, airway defense mechanisms, pathogenesis, imaging and genetic causes of bronchiectasis are discussed. Allergic bronchopulmonary aspergillosis is addressed, as well as non-tuberculous mycobacteria as a cause of bronchiectasis. Authors examine how to evaluate the success of therapy for bronchiectasis (what endpoints to use) and then discuss a variety of therapy options: inhaled and systemic antibiotic treatment, chest physiotherapy, pharmacologic agents for mucous clearance, antipinflammatory therapy and macrolides. Pulmonary resection and lung transplantation for bronchiectasis are reviewed. Recent advances in Cystic Fibrosis are also discussed.

Drs. Huitt and Daley have assembled an expert panel of authors on the topic of Non-Tuberculosis Mycobacteria. Articles in this issue will include discussions in the following areas: The Pathogenesis of NTM, Epidemiology of NTM, Environmental Sources of NTM, Laboratory Diagnosis of NTM, Medications and Monitoring in NTM infections, Treatment of Rapidly Growing NTM, Treatment of Slow Growing NTM, NTM Infections in Immunocompromised Hosts, Extra Pulmonary NTM Infections, NTM Infections in Cystic Fibrosis, and Surgical Approach to NTM Infections.

In this issue of Clinics in Chest Medicine, guest editors Drs. Shannon Kasperbauer and Rachel Thomson bring their considerable expertise to the topic of Nontuberculous Mycobacterial Pulmonary Disease. Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a challenging infection which is becoming increasingly prevalent, particularly in the elderly, for reasons which are unknown. In this issue, top experts discuss topics such as environmental sources and transmission of nontuberculous mycobacteria; global epidemiology; host susceptibility; investigation and management of bronchiectasis in nontuberculous mycobacterial pulmonary disease; and more. - Contains 15 practice-oriented topics including novel antimicrobial agents in nontuberculous pulmonary disease; host directed therapy in nontuberculous pulmonary disease; cystic fibrosis related nontuberculous mycobacterial pulmonary disease; surgical resection in nontuberculous mycobacterial pulmonary disease; and more. - Provides in-depth clinical reviews on nontuberculous mycobacterial pulmonary disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This issue of Clinics in Chest Medicine, edited by Dr. Denis O'Donnell and Dr. Alberto Neder, focuses on Clinical Respiratory Physiology. Articles include: The Pathophysiology of Obstructive Sleep Apnea; The Physiology of Mechanical Ventilation; Exercise Pathophysiology in Congestive Heart Failure; Control of Breathing; Breathing at Extremes; Exercise Pathophysiology in Interstitial Lung Disease; Importance of Physiology in Clinical Decision-Making in the ICU; Pulmonary Hypertension and Exercise; Physiologic Effects of Oxygen Supplementation During Exercise in COPD; Benefits and Pitfalls of DLCO measurements in Clinical Practice; Cardio-pulmonary Interactions in COPD-CHF; Exercise Physiology in COPD; Dyspnea of Unknown Origin: The Role of Exercise Testing; Assessment of Ventilatory Limitation During Exercise; Respiratory Muscle Assessment in Clinical Practice; Exertional Periodic Breathing in Heart Failure; and Strategies to Increase Physical Activity in Chronic Respiratory Diseases

In this issue of Clinics in Chest Medicine, guest editors Drs. Luis Angel and Stephanie M. Levine bring their considerable expertise to the topic of Lung Transplantation. Top experts in the field cover key topics such as difficult decisions to transplant patients who are older, frail, underweight and obese; organ donation and variability in conversion to lung transplantation; conventional and novel approaches to immunosuppression; acute rejection and chronic allograft dysfunction; and more. - Contains 14 relevant, practice-oriented topics including COVID-19 and lung transplantation; the lung transplant candidate: indications, timing and selection criteria; bilateral lung transplantation vs. single lung transplant: complications, quality of life, and survival; critical care management of the lung transplant recipient; and more. - Provides in-depth clinical reviews on lung transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Clinics in Chest Medicine, Guest Editors Harold R Collard, Luca Richeldi, and Kerri A. Johannson bring their considerable expertise to the topic of Next-generation Interstitial Lung Disease. Provides concise and comprehensive coverage of the issues physicians face every day. Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field.