Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered: 1) RARE case with TYPICAL features 2) FREQUENT case with ATYPICAL features 3) Cases with a convincing response to new treatments, i.e. single case of off-label use

This Research Topic aims to collect all the Case Reports submitted to the General Cardiovascular Medicine section. All the Case Reports submitted to this collection will be personally assessed by the Specialty Chief Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it. Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered: 1) RARE case with TYPICAL features 2) FREQUENT case with ATYPICAL features 3) Cases with a convincing response to new treatments, i.e. single case of off-label use

Coronary artery disease remains a principal cause of morbidity and mortality worldwide. During the last decade, both non-invasive and invasive imaging techniques, as well as assessment of coronary physiology and hemodynamics have provided significant prognostic information and improved the identification of high-risk patients and coronary lesions. The goal of this special edition Research Topic is to shed light on the progress made in the prediction of adverse coronary events, and on its future challenges to provide a thorough overview of the field. This article collection will inspire, inform and provide direction and guidance to researchers and clinicians in the field.

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management comprehensively covers COVID-19's impact on the cardiovascular system. Coverage includes the pathophysiology, clinical manifestations, diagnostic approach, treatment options, and clinical outcomes of patients presenting with COVID-19 with cardiac involvement. In a concise but comprehensive manner, the book's content reviews the epidemiology, risk factors, pathophysiology of COVID-19, cardiovascular clinical manifestations, non-invasive and invasive diagnostic evaluation, therapeutic options, outcomes data, role of the COVID-19 vaccine, and long-term outcomes/management.This is the perfect reference for basic and clinical researchers in cardiovascular medicine as well as practicing clinical cardiologists who are dealing with COVID-19 patients with cardiac involvement. - Explains the pathophysiology, clinical manifestations, diagnostic approach, treatment options, and clinical outcomes of patients presenting with COVID-19 and cardiac involvement - Elucidates new and emerging options to treat this disease process - Provides concise, well validated, published data available in one single resource