Sequential and reciprocal interactions between oral epithelial and cranial neural crest-derived mesenchymal cells give rise to the teeth and periodontium. Teeth are vital organs containing a rich number of blood vessels and nerve fibers within the dental pulp and periodontium. Teeth are composed by unique and specific collagenous (dentin, fibrillar cementum) and non-collagenous (enamel) highly mineralized extracellular matrices. Alveolar bone is another collagenous hard tissue that supports tooth stability and function through its close interaction with the periodontal ligament. Dental hard tissues are often damaged after infection or traumatic injuries that lead to the partial or complete destruction of the functional dental and supportive tissues. Well-established protocols are routinely used in dental clinics for the restoration or replacement of the damaged tooth and alveolar bone areas. Recent progress in the fields of cell biology, tissue engineering, and nanotechnology offers promising opportunities to repair damaged or missing dental tissues. Indeed, pulp and periodontal tissue regeneration is progressing rapidly with the application of stem cells, biodegradable scaffolds, and growth factors. Furthermore, methods that enable partial dental hard tissue repair and regeneration are being evaluated with variable degrees of success. However, these cell-based therapies are still incipient and many issues need to be addressed before any clinical application. The understanding of tooth and periodontal tissues formation would be beneficial for improving regenerative attempts in dental clinics. In the present e-book we have covered the various aspects dealing with dental and periodontal tissues physiology and regeneration in 6 chapters: 1. General principles on the use of stem cells for regenerating craniofacial and dental tissues 2. The roles of nerves, vessels and stem cell niches in tissue regeneration 3. Dental pulp regeneration and mechanisms of various odontoblast functions 4. Dental root and periodontal physiology, pathology and regeneration 5. Physiology and regeneration of the bone using various scaffolds and stem cell populations 6. Physiology, pathology and regeneration of enamel using dental epithelial stem cells

Oral Anatomy, Histology and Embryology is unique in offering easy-to-understand explanations of all three of these complex topics in the one book.This popular textbook is designed to help students develop a deep understanding of these subjects to support their study and future clinical careers. Learning is made easy with clear diagrams, photographs and explanations.Now in its sixth edition, the book has been fully updated to incorporate latest developments in the field. It provides full coverage of topics including tooth morphology, functional anatomy, oro-dental histology, craniofacial and oral development and clinical considerations.Key Features: - Over 1,000 images including schematic artworks, radiological images, electron-micrographs, cadaveric and clinical photographs and memory maps – all specially selected to make learning and recall as easy as possible - Numerous clinical case histories help relate the basic science to clinical practice - Includes comprehensive coverage of the soft tissues of the oral region and skeletal structures of the head, including vasculature and innervation - Includes information on mastication, swallowing, speech, radiology and archaeological applications of tooth structure - Addresses physical, chemical and structural properties of the tooth (enamel, dentine, pulp and cementum) and of the periodontium and oral mucosa - Explores bone structure and remodelling – including potential bone atrophy following tooth extraction, its relevance to orthodontic treatment and implantology, trauma and malignancy - Images and text have been considered in terms of human diversity - Online self-assessment quizzes supports learning and exam preparation - Online bibliography for each topic provides options for further reading - An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud - New chapter on reparative and regenerative dentistry - Memory maps to support learning

Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry. The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues. - Connects materials science with restorative dentistry - Focuses on the unique field of intraoral tissues - Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues

Dental and craniofacial treatments are actually based on advances in biomaterials, tissue engineering and nanotechnology sciences. These developments brought considerable improvements on biomaterials commonly used in dental clinics. However, there is still a medical need for innovative techniques and materials for a controllable and efficient regeneration/repair of damaged craniofacial tissues and teeth. The novel biomaterials, imaging techniques, diagnostic and technological tools may offer thrilling perspectives for alternative treatments in dentistry.

This book equips dental practitioners with all the information required in order to ensure successful endodontic treatment of children and adolescents. It describes pulp therapy from a holistic approach that highlights new developments in the field. Readers will find updates on the formation, structure and function of the dental pulp revealed by the latest single-cell technologies, and discussions on carious lesions and their impact on the pulp. The book examines clinical considerations in the decision to perform pulp treatment and emphasizes the need to integrate pupal diagnostics with patient-dependent factors such as behavior management and pulpal pain mechanisms. The second part of the book includes comprehensive descriptions of current treatments for each type of caries-inflicted tooth damage, from selective caries removal through direct pulp capping, pulpotomy, pulpectomy and root canal therapy for primary dentition to direct pulp capping and endodontic treatment of young permanent teeth. Traditional and new pulp-treatment materials are described as are the techniques and materials used to restore both primary and young permanent teeth. The book summarizes innovative biological approaches for pulp regeneration such as the use of stem cells. It is a must have for dental students, endodontists, pediatric dentists and general dentists with an interest in the subject.

BIODEGRADABLE MATERIALS AND THEIR APPLICATIONS Biodegradable materials have ascended in importance in recent years and this book comprehensively discusses all facets and applications in 29 chapters making it a one-stop shop. Biodegradable materials have today become more compulsory because of increased environmental concerns and the growing demand for polymeric and plastic materials. Despite our sincere efforts to recycle used plastic materials, they ultimately tend to enter the oceans, which has led to grave pollution. It is necessary, therefore, to ensure that these wastes do not produce any hazards in the future. This has made an urgency to replace the synthetic material with green material in almost all possible areas of application. Biodegradable Materials and Their Applications covers a wide range of subjects and approaches, starting with an introduction to biodegradable material applications. Chapters focus on the development of various types of biodegradable materials with their applications in electronics, medicine, packaging, thermoelectric generations, protective equipment, films/coatings, 3D printing, disposable bioplastics, agriculture, and other commercial sectors. In biomedical applications, their use in the advancement of therapeutic devices like temporary implants, tissue engineering, and drug delivery vehicles are summarized. Audience Materials scientists, environmental and sustainability engineers, and any other researchers and graduate students associated with biodegradable materials.

Stay updated on the latest advancements in periodontal care with this comprehensive guide. Covering new treatments, technologies, and research in gum health, this book is an invaluable resource for dental practitioners and researchers.

Tissue Engineering: Current Status and Challenges bridges the gap between biomedical scientists and clinical practitioners. The work reviews the history of tissue engineering, covers the basics required for the beginner, and inspires those in the field toward future research and application emerging in this fast-moving field. Written by global experts in the field for those studying and researching tissue engineering, the book reviews regenerative technologies, stem cell research and regeneration of organs. It then moves to soft tissue engineering (heart, vascular, muscle and 3D scaffolding and printing), hard tissue engineering (bone, dental myocardial and musculoskeletal) and translational avenues in the field. - Introduces readers to the history and benefits of tissue engineering - Includes coverage of new techniques and technologies, such as nanotechnology and nanoengineering - Presents concepts, ideology and theories which form the foundation for next-generation tissue engineering

Master the use of dental materials in the clinic and dental laboratory and stay current with this ever-changing field with Craig's Restorative Dental Materials, 13th Edition. From fundamental concepts to advanced skills, this comprehensive text details everything you need to know to understand the scientific basis for selecting dental materials when designing and fabricating restorations. This practical, clinically relevant approach to the selection and use of dental materials challenges you to retain and apply your knowledge to realistic clinical scenarios, giving you an authoritative advantage in dental practice. - Problems and Solutions at the end of each chapter test your ability to apply chapter concepts to solve common clinical challenges. - Mind Maps on the companion Evolve website condense essential chapter content into single-page overviews ideal for quick reference, study outlines, or comprehensive reviews. - Comprehensive coverage reflects fundamental concepts and the latest practical knowledge all in one authoritative source. - Appendix of useful resource materials provides quick, convenient access to Weights and Measurements, Conversion Tables, and Comparative Table of Troy, Avoirdupois, and Metric Weights. - Content updates and links on Evolve keep you current with the latest developments in the field. - NEW! Full-color design and illustrations clarify clinical detail for greater understanding. - NEW! Reorganized content emphasizes scientific evidence and is organized by usage in a clinical setting to help you study more efficiently. - NEW! Digital Imaging and Processing for Restorations chapter equips you with essential understanding of current imaging practices. - NEW! Major revisions reflect the latest advances in the use of enamel, dental, biofilms, mechanical testing, ceramics, polymers, and composites.

This book provides evidence-based information in the field of regenerative dentistry discussing the most recent advances, current clinical applications, limitations and future directions. The coverage encompasses the regeneration of alveolar bone, the dentine-pulp complex, enamel, the periodontium and other tissues associated with the oral cavity. A full description is provided of regenerative approaches in dentistry including regenerative endodontics and tooth repair, regenerative periodontics, regenerative assisted orthodontics, regenerative approaches in oral medicine, and dental tissue derived stem cells and their potential applications. The book is written by an international team of leading experts. It will be beneficial for students, practitioners and researchers in the fields of endodontics, periodontics and implantology.