This book provides evidence-based information in the field of regenerative dentistry discussing the most recent advances, current clinical applications, limitations and future directions. The coverage encompasses the regeneration of alveolar bone, the dentine-pulp complex, enamel, the periodontium and other tissues associated with the oral cavity. A full description is provided of regenerative approaches in dentistry including regenerative endodontics and tooth repair, regenerative periodontics, regenerative assisted orthodontics, regenerative approaches in oral medicine, and dental tissue derived stem cells and their potential applications. The book is written by an international team of leading experts. It will be beneficial for students, practitioners and researchers in the fields of endodontics, periodontics and implantology.

This book provides evidence-based information in the field of regenerative dentistry discussing the most recent advances, current clinical applications, limitations and future directions. The coverage encompasses the regeneration of alveolar bone, the dentine-pulp complex, enamel, the periodontium and other tissues associated with the oral cavity. A full description is provided of regenerative approaches in dentistry including regenerative endodontics and tooth repair, regenerative periodontics, regenerative assisted orthodontics, regenerative approaches in oral medicine, and dental tissue derived stem cells and their potential applications. The book is written by an international team of leading experts. It will be beneficial for students, practitioners and researchers in the fields of endodontics, periodontics and implantology.

Sequential and reciprocal interactions between oral epithelial and cranial neural crest-derived mesenchymal cells give rise to the teeth and periodontium. Teeth are vital organs containing a rich number of blood vessels and nerve fibers within the dental pulp and periodontium. Teeth are composed by unique and specific collagenous (dentin, fibrillar cementum) and non-collagenous (enamel) highly mineralized extracellular matrices. Alveolar bone is another collagenous hard tissue that supports tooth stability and function through its close interaction with the periodontal ligament. Dental hard tissues are often damaged after infection or traumatic injuries that lead to the partial or complete destruction of the functional dental and supportive tissues. Well-established protocols are routinely used in dental clinics for the restoration or replacement of the damaged tooth and alveolar bone areas. Recent progress in the fields of cell biology, tissue engineering, and nanotechnology offers promising opportunities to repair damaged or missing dental tissues. Indeed, pulp and periodontal tissue regeneration is progressing rapidly with the application of stem cells, biodegradable scaffolds, and growth factors. Furthermore, methods that enable partial dental hard tissue repair and regeneration are being evaluated with variable degrees of success. However, these cell-based therapies are still incipient and many issues need to be addressed before any clinical application. The understanding of tooth and periodontal tissues formation would be beneficial for improving regenerative attempts in dental clinics. In the present e-book we have covered the various aspects dealing with dental and periodontal tissues physiology and regeneration in 6 chapters: 1. General principles on the use of stem cells for regenerating craniofacial and dental tissues 2. The roles of nerves, vessels and stem cell niches in tissue regeneration 3. Dental pulp regeneration and mechanisms of various odontoblast functions 4. Dental root and periodontal physiology, pathology and regeneration 5. Physiology and regeneration of the bone using various scaffolds and stem cell populations 6. Physiology, pathology and regeneration of enamel using dental epithelial stem cells

In this issue of Dental Clinics, guest editors Alpdogan Kantarci, Andreas Stavropoulos, and Anton Sculean bring their considerable expertise to the topic of Biologics and Biology-based Regenerative Treatment Approaches in Periodontics. - Provides in-depth, clinical reviews on the latest updates in Biologics and Biology-based Regenerative Treatment Approaches in Periodontics, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.

Essential Techniques of Alveolar Bone Augmentation in Implant Dentistry A clinically focused manual of the most important surgical techniques in alveolar bone augmentation, providing key information for managing cases in implant dentistry The second edition of Essential Techniques of Alveolar Bone Augmentation in Implant Dentistry: A Surgical Manual, Second Edition presents a variety of key surgical bone augmentation techniques for ensuring proper bone width and height for dental implant placement. Enabling clinicians and dental students to rapidly locate information for cases requiring bone augmentation, this highly practical reference covers ridge preservation, horizontal and vertical ridge augmentation, soft tissue grafting for implant site development, tissue engineering techniques, and surgical alternatives to bone grafting in implant dentistry. Succinct chapters written by a panel of more than 40 international leading clinicians, scientists, and teachers include step-by-step descriptions of each surgical procedure—supported by information on diagnosis and treatment planning and more than 1,000 high-quality clinical images and illustrations. This fully up to date second edition includes new coverage of 3D alveolar ridge defect reconstruction, procedures for vertical bone augmentation in the posterior maxilla, complete arch dental implant treatment using photogrammetry, metal-ceramic transitional maxillary implant rehabilitation, ridge-split expansion using piezoelectric surgery, and more. Presents the main techniques for horizontal and vertical alveolar ridge augmentation Contains essential clinical knowledge on bone biology, radiographic and prosthetic evaluation, incision designs, and wound closure Introduces alternative techniques such as zygomatic implants, pterygoid implants, and All-on-4 procedure for placement of dental implants that circumvent bone grafting Combines the most practical and efficient techniques from the First Edition of Horizontal Augmentation of the Alveolar Ridge in Implant Dentistry and Vertical Augmentation of the Alveolar Ridge in Implant Dentistry in a single and concise book Essential Techniques of Alveolar Bone Augmentation in Implant Dentistry: A Surgical Manual, Second Edition is a must-have for both novice and experienced dental clinicians, implant dentists, oral surgeons, prosthodontists, and periodontists, and an invaluable resource for dental students and trainees.

This richly illustrated book combines explanation of the scientific base underpinning vital pulp treatment with description of current and emerging trends in clinical practice. It guides the reader through modern views on pulp diagnostics, deep caries, and pulp exposure management, leading to an analysis of the biological aspects of regenerative techniques such as angiogenesis, neurogenesis, inflammation, and epigenetics. In the later chapters, practical considerations relating to bioengineering, biomaterial choice, revitalization, and stem cell-based procedures are discussed and their likely therapeutic impact considered. Aimed at dental students, postgraduates, and research-minded dental practitioners, this translational book summarizes state-of-the-art scientific knowledge on dentin–pulp interactions and regenerative endodontics, while highlighting the opportunities to incorporate recent developments into everyday practice. Readers will also find extensive discussion of potential future developments and research avenues relating to each aspect of this exciting and rapidly developing field.

Dental and craniofacial treatments are actually based on advances in biomaterials, tissue engineering and nanotechnology sciences. These developments brought considerable improvements on biomaterials commonly used in dental clinics. However, there is still a medical need for innovative techniques and materials for a controllable and efficient regeneration/repair of damaged craniofacial tissues and teeth. The novel biomaterials, imaging techniques, diagnostic and technological tools may offer thrilling perspectives for alternative treatments in dentistry.

The concept of scaffolds in tissue engineering has revolutionized the approach to periodontal therapy. This book delves into the various types of scaffolds, their biological and mechanical properties, and the innovative materials being utilized to enhance their effectiveness. This book addresses the integration of scaffold technology with other regenerative modalities such as growth factors, stem cells, and gene therapy. The synergistic effects of these combined approaches hold immense promise for the future of periodontal regeneration. This book covers topics related to the biological and mechanical aspects of scaffold use in regeneration .