This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.

CHAPEL AND HAENEY’S ESSENTIALS OF CLINICAL IMMUNOLOGY The Essentials are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wiley.com for further details. The fully updated new edition of the classic textbook, introducing the pathophysiology and management of immunological disorders Chapel and Haeney’s Essentials of Clinical Immunology contains the knowledge necessary to understand the diagnosis and treatment of immunological disorders. With easy-to-read text and a wealth of colour clinical images and diagrams, this well-regarded textbook introduces complex concepts using effective pedagogical tools such as bulleted lists, key point boxes, real-life case studies, practical examples, figures and tables, chapter introductions, and keywords in bold integrated in each chapter. Fully updated throughout, the seventh edition provides up-to-date coverage of the clinical relevance that immunology has in medicine. These new and revised sections examine current research trends, the implementation of automation in laboratories, the emerging field of neuro-psychiatric disorders such as NMDA receptor encephalitis and more. This edition includes new end-of-chapter summaries, updated clinical information, additional real-life case histories illustrating key concepts, and linking immunological testing to diseases. The new edition also includes: Covers the investigations required for diagnosis of immunological disorders and for management of patients Describes what occurs when diagnosing conditions in real-world laboratories Features case studies highlighting the connections between immunological theory and clinical cases Includes an updated companion website that features: case studies, interactive questions, photographs, illustrations, web links and review articles from the journal Clinical and Experimental Immunology Chapel and Haeney’s Essentials of Clinical Immunology is an ideal resource for clinical medical students, junior doctors, medical residents and other medical professionals who are looking to expand or refresh their knowledge in clinical immunology, as well as being an excellent introductory textbook for undergraduate courses in the subject. For more information on the complete range of Wiley medical student and junior doctor publishing, please visit: www.wiley.com To receive automatic updates on Wiley books and journals, join our email list. Sign up today at www.wiley.com/email All content reviewed by students for students Wiley Medical Education books are designed exactly for their intended audience. All of our books are developed in collaboration with students. This means that our books are always published with you, the student, in mind If you would like to be one of our student reviewers, go to www.reviewmedicalbooks.com to find out more. This title is also available as an e-book. For more details, please see www.wiley.com/buy/9781119542384

Apoptosis Regulatory Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Apoptosis Regulatory Proteins. The editors have built Apoptosis Regulatory Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Apoptosis Regulatory Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Apoptosis Regulatory Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The definitive guide to putting spinal cord injury research into practice Essentials of Spinal Cord Injury is written for the spinal cord injury (SCI) team and reflects the multidisciplinary nature of treating patients with SCI. It integrates emerging medical and surgical approaches to SCI with neuroanatomy, neurophysiology, neuroimaging, neuroplasticity, and cellular transplantation. This comprehensive yet concise reference will enable neurosurgeons, orthopedic surgeons, neurologists, and allied health professionals caring for SCI patients to translate research results into patient care. It is also an excellent resource for those preparing for the board exam in SCI medicine. Key Features: Material is cross-referenced to highlight relationships between the different areas of SCI Chapters are concise, focused, and include key points, pearls, and pitfalls An Overview of the Literature table is provided in most chapters, giving readers a meaningful distillation of each publication referenced Each editor is a world-renowned expert in one of these core disciplines involved in the management of SCI patients: neurosurgery, orthopedic surgery, spinal cord science, and rehabilitative medicine This is a must-have guide that all neurosurgeons, orthopedic surgeons, neurologists, and allied health professionals involved in the care of spinal cord injury patients should have on their bookshelf.

GIVING NURSES THE PATHOPHYSIOLOGY KNOWLEDGE TO THRIVE IN MODERN PRACTICE Combining all the benefits of traditional textbook learning with additional videos and online resources that take you further. Using the person-centred practice framework as its guiding principle, the book explores the scientific principles that underpin health, illness and the main causes of disease. It covers specific disorders, including a new section on the pathology of Covid-19, and applies theory to practice throughout. Key features: See and learn: over 100 integrated video links providing insights and short explanations Full-colour diagrams and figures: all chapters supported by colourful, reader-friendly illustrations. Person-centred bioscience: a fictional family woven through the book encourages students to think holistically about pathophysiology and consider the lived-experiences of different conditions and illnesses. Online resources: access to online materials for lecturers and students, including multiple choice questions, video links, flashcards, a lecturer test bank, image bank and a media teaching guide.

Key Benefit: Known for its focus on problem-solving, conceptual understanding, and practical applications, this best-seller is 32 pages shorter than its previous edition. New features of the Seventh Edition include new “Exploring Genomics” exercises for selected chapters, in-chapter summaries that follow concept introductions for efficient review, engaging case studies in each chapter, an expanded Companion Website with myeBook, and a new chapter on Behavioral Genetics. Key Topics: Introduction to Genetics, Mitosis and Meiosis, Mendelian Genetics, Modifications of Mendelian Ratios, Sex Determination and Sex Chromosomes, Chromosome Mutations: Variation in Number and Arrangement, Linkage and Mapping in Eukaryotes, Genetic Analysis and Mapping in Bacteria and Phage, DNA Structure and Analysis, DNA Replication and Recombination, Chromosome Structure and DNA Sequence Organization, The Genetic Code and Transcription, Translation and Proteins, Gene Mutation, DNA Repair, and Transposable, Regulation of Genetic Expression, Cancer and the Regulation of the Cell Cycle, Recombinant DNA Technology and Gene Cloning, Genomics and Proteomics, Applications and Ethics of Genetic Engineering and Biotechnology, Developmental Genetics, Genetics and Behavior, Quantitative Genetics, Population and Evolutionary Genetics, Conservation Genetics Market: Intended for those interested in learning the basics of genetics

Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This book presents research from around the world.

This book introduces readers to the molecules involved in apoptosis and genomal integrity and considers the gain or loss of the functions that lead to cancer.

Essential Orthopedics: Principles & Practice is an extensive, illustrated guide to the field of orthopaedics. Principles and practice for shoulder, hip, spine, hand, foot and ankle are covered, including anatomy, physiology, pathology and diseases. Essential Orthopedics: Principles & Practice includes all modern research methodologies, such as biostatistics, advanced imaging and gene therapy. Enhanced by 2000 full colour illustrations this is a comprehensive resource for all interns, residents and orthopaedic surgeons.