Seminal resource on state-of-the-art flow diversion techniques from leading neurointerventional experts From detachable balloons and GDC coils to the recent advent of flow diversion, practitioners of endovascular neurosurgery have been fortunate to work in an era of rapid and exciting advances. The first commercially available flow diverter in the U.S. was approved specifically for a small subset of cerebral aneurysms. Recent experience has demonstrated its utility in treating challenging or otherwise untreatable aneurysms, safely and efficaciously. The design of these devices requires learning radically different methods than those used in the deployment of other, non-braided stents. Flow Diversion of Cerebral Aneurysms by Min Park, Philipp Taussky, Felipe Albuquerque, and Cameron McDougall provides step-by-step guidance on utilization of flow diversion technology in clinical practice. Reflecting the combined experience and knowledge of pioneers in neurointerventional surgery, this comprehensive book fills a gap in available resources. Twenty-one chapters cover fundamentals to advanced concepts – historical perspective to future developments. Key Features More than 100 high quality graphics and illustrative case studies reinforce key concepts Techniques and nuances of Pipeline, Silk (Balt Extrusion), Surpass Streamline, and Flow-Redirection Endoluminal Device (FRED) deployment An overview of current flow diversion devices, discussion of coil embolization versus flow diversion, off-label uses, adjuvant approaches, and hemodynamic modifications Pharmacology, flow diversion grading scales, and post-procedure radiographic imaging Clinical pearls on ruptured aneurysms, intraprocedural/postprocedural complications, and management of aneurysm residuals The ultimate goal of incorporating cutting-edge flow diversion techniques into the aneurysm treatment paradigm is improved efficacy and patient outcome. The knowledge gleaned from this outstanding resource will help residents and fellows learn to deploy flow diverters for the first time and enable seasoned clinicians to expand their neurointerventional radiology skills.

This book provides recent progress of neuroendovascular surgery, which is a minimally invasive treatment of cerebral aneurysms. Great advances have been made in the techniques, devices and large randomized clinical trials showing striking therapeutic benefit for cerebral aneurysms. The treatment of cerebral aneurysms has also seen substantial evolution, increasing the number of aneurysms that can be treated successfully with minimally invasive therapy. In the 17 chapters, authors introduce the techniques, devices, device structures and therapeutic concepts. Attendings, fellows, residents, medical students or anyone interested in sharpening their diagnostic and therapeutic skill set will benefit from reading this text. This book will include many clinical cases and skills and clinical concepts, which will benefit professional /practitioner.

With the publications of the International subarachnoid aneurysm trial (ISAT), endovascular treatment has become one of the most important treatments of intracranial aneurysms, and was used more and more in clinic settings. However, intracranial complex aneurysms (such as giant aneurysms, wide-necked aneurysms, fusiform aneurysms and dissecting aneurysms) still impose a huge challenge for clinicians. Flow diverter (FD) is a novel device for the treatment of aneurysms based on the understanding of hemodynamic mechanism of aneurysm occlusion. It could divert the blood flow from the aneurysm neck, and promote aneurysm occlusion without inserting coils into the aneurysms. In addition, the FDs had the advantage of simplifying the procedure and relieving the mass effect.

Intracranial aneurysm result from complex interactions between cerebrovascular anatomy, vascular injury, and adaptive remodeling of the arterial wall and represent a cerebrovascular disorder with the potential for substantial morbidity and mortality. Most intracranial aneurysms occur in the larger arteries near the skull base, in or around the circle of Willis, but variants may appear virtually anywhere in the cerebral vasculature. The aneurysm can leak or rupture, causing life-threatening bleeding, and is the most common cause of spontaneous subarachnoid hemorrhage, the third most common form of stroke. Intracranial aneurysms affect about 1 in 10,000 people per year in the United States (approximately 27,000). Intracranial Aneurysms will address the natural history, biology, and basic management principles and treatment of aneurysms. The chapters also explore the unique features of each type or location of aneurysm while considering the medical, surgical, and endovascular options. Contributions are by members of the Endovascular Neurosurgery Research Group, a group of recognized expert neurosurgeons who specialize in cerebrovascular and endovascular management of aneurysms. - Comprehensively covers the basic mechanisms, history, management and treatment of intracranial aneurysms - Written for researchers, residents and clinical practitioners in clinical neuroscience, neurology and neurosurgery - Contains contributions by expert neurosurgeons of the Endovascular Neurosurgery Research Group

This atlas focuses on the imaging and treatment options available for giant intracranial aneurysms since 1990s in the beginning of the so-called modern endovascular era. During this period, there were significant advances made in the therapy of small intracranial aneurysms though the treatment of giant aneurysms continued to pose an insurmountable challenge. At the turn of this century, this grim scenario gradually improved with better understanding of the pathophysiology of giant intracranial aneurysms. This changed scenario in giant intracranial aneurysm therapy has been illustrated with the aid of informative clinical case studies. The clinical presentation of giant aneurysms in adults and children is described as are the merits of different imaging modalities explained and illustrated. Extensive consideration has been given to modern fusion imaging that has improved our insight into the nature of the disease. Endovascular treatment approaches (including illustrative open surgical approaches) and reconstructive and deconstructive strategies are fully documented, with careful attention given to factors that influence management strategies, treatment choice and complications.The atlas will be a valuable reference and practical aid for neuroradiologists, neurosurgeons, neurologists, fellowship trainees, postgraduate & graduate students.

This fourth edition offers a practical guide to endovascular treatment of cerebrovascular disease and provides a comprehensive reference for the related neurovascular anatomy and the various disorders that affect the vascular system. Chapters cover fundamental principles underlying cerebral and spinal angiography; interventional techniques, devices, and practice guidelines; and commonly encountered cerebrovascular disorders for which interventional and endovascular methods are appropriate Building on the previous edition, the text is presented similarly in style and scope to emphasize accessibility and ease of reading. All chapters are fully updated to include more recent data, and obsolete products and techniques are replaced with the most current technology. Some key updates include: A greater emphasis on the use of radial artery access for the discussed endovascular techniques. The associations of COVID-19 with ischemic stroke and the implications of providing care for cerebrovascular patients during a pandemic. An extensive update to the acute ischemic stroke chapter with new references and format to more closely follow the format of other chapters in that section. Expansion of the pediatric sections of disease chapters, including discussions of genetic associations with disease. This is an ideal guide for clinicians and trainees in neurology, neurosurgery and neuroradiology, as well as practicing clinicians in related fields caring for patients with cerebrovascular disease.

This book introduces the basic tenets and technique skills for endovascular embolization and provides the most up-to-date technical advancements, treatment strategy evolution, and literature review related to the endovascular treatment of brain aneurysms. The most special feature of this book is how the content is organized. The morphology, instead of the location, dictates the treatment strategy applied and procedure skills required for the endovascular treatment of brain aneurysms. Hence, the book is structured with a new conceptual way of classifying aneurysms into eight different types based on the morphological characteristics of brain aneurysms. The specific technical skills and treatment strategies for these different aneurysm categories are described separately in their own chapters. Another important feature of the book is the combination of detailed technical descriptions of the skills, strategies, and advancement in the field accompanied with case presentations. The large and comprehensive collection of the case presentations further enhances the points in the text. This book can be used as a handbook on endovascular treatment of brain aneurysms. It can also help physicians in the early careers of these subspecialties for their daily practice and board preparation. The text will provide the most up-to-date knowledge for more experienced endovascular neurosurgeons and interventionalists on the topics of new techniques and endovascular products. Additionally, it can also serve as a practice guidance resource for nurse practitioners and physician assistants of the above subspecialties.

This updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors — Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong — head the sixth edition of this classic text, which is authored by the world’s foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use.