With over 80 information-packed chapters, Handbook for Clinical Research delivers the practical insights and expert tips necessary for successful research design, analysis, and implementation. Using clear language and an accessible bullet point format, the authors present the knowledge and expertise developed over time and traditionally shared from mentor to mentee and colleague to colleague. Organized for quick access to key topics and replete with practical examples, the book describes a variety of research designs and statistical methods and explains how to choose the best design for a particular project. Research implementation, including regulatory issues and grant writing, is also covered. The book opens with a section on the basics of research design, discussing the many ways in which studies can be organized, executed, and evaluated. The second section is devoted to statistics and explains how to choose the correct statistical approach and reviews the varieties of data types, descriptive and inferential statistics, methods for demonstrating associations, hypothesis testing and prediction, specialized methods, and considerations in epidemiological studies and measure construction. The third section covers implementation, including how to develop a grant application step by step, the project budget, and the nuts and bolts of the timely and successful completion of a research project and documentation of findings: procedural manuals and case report forms; collecting, managing and securing data; operational structure and ongoing monitoring and evaluation; and ethical and regulatory concerns in research with human subjects. With a concise presentation of the essentials for successful research, the Handbook for Clinical Research is a valuable addition to the library of any student, research professional, or clinician interested in expanding the knowledge base of his or her field. Key Features: Delivers the essential elements, practical insights, and trade secrets for ensuring successful research design, analysis, and implementation Presents the nuts and bolts of statistical analysis Organized for quick access to a wealth of information Replete with practical examples of successful research designs ó from single case designs to meta-analysis - and how to achieve them Addresses research implementation including regulatory issues and grant writing

This handbook is a definitive, up-to-date, and succinct text covering the legislative requirements, scientific foundations, and clinical good practice necessary for clinical, academic, and healthcare research.

Law/Ethics

The aim of this unique volume is to help medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease. Written in a user-friendly step-by-step format, this work enables the researcher-with no background in statistics-to determine sample size and write statistical considerations for their protocols. It provides critical language which can help with FDA submissions and/or research grants. It also provides the mathematical justification of the material at a level consistent with one year of undergraduate mathematical statistics. It presents survival analysis methods at a more elementary level than any known text. Filled with tables, figures, plus an extensive appendix, this one-of-a-kind reference is an absolute must for all clinical researchers and biostatisticians.

The Oxford Handbook of Research Strategies for Clinical Psychology has recruited some of the field's foremost experts to explicate the essential research strategies currently used across the modern clinical psychology landscape that maximize both scientific rigor and clinical relevance.

The Handbook of Research Methods in Clinical Psychology presents a comprehensive and contemporary treatment of research methodologies used in clinical psychology. Topics discussed include experimental and quasi-experimental designs, statistical analysis, validity, ethics, cultural diversity, and the scientific process of publishing. Written by leading researchers, the chapters focus on specific applications of research into psychopathology, assessment and diagnosis, therapy, and interventions for both child and adult populations. Special attention is also given to research into professional issues, prevention, and promotion. Research vignettes describe exemplary projects illustrating the essential elements of the research topics. In addition, the editors outline a research agenda for clinical psychologists that demonstrates the exciting future for the field. This handbook coherently illustrates the range of research methodologies used in clinical psychology and is a vital resource for both students and scholars who wish to expand their knowledge. Covers basic methodologies as well as specific applications of research designs. Includes research vignettes that describe exemplary studies and illustrate the essential elements of the research topics. Contains chapters written by active researchers in the field. Outlines a research agenda for clinical psychologists that demonstrates the exciting future for the field. Now available in full text online via xreferplus, the award-winning reference library on the web from xrefer. For more information, visit www.xreferplus.com

In this fully revised and expanded fourth edition of the essential reference for clinical research coordinators, Deborrah Norris provides expanded coverage of CRC duties and regulatory requirements, including new sections on investigator responsibilities, data clarification, and adverse event reporting. The book s five appendices include a directory of CRC resources, updated forms and checklists, state regulatory requirements and contact information, conversion charts and tables, and a glossary.

With the increasing emphasis on evidence-based practice, there is a need for all health and social care professionals to understand the principles of general and clinical research. In the United Kingdom and several other countries, this had led to a proliferation of advanced programs, including for those seeking doctorate degrees. In this book, the editors introduce readers to the principles and practice of clinical research. Eighteen chapters and three appendices provide guidance on the different stages of a research project, from inception to the dissemination of results. Topics include: • steps to engage in practice-based research; • ethical questions surrounding research; • sources of funding; • collecting and collating data. Contributing authors emphasize the need to critically appraise literature before carrying out a research project. They also explain the stages of a research project and share insights on where to go for more information. The book includes an index, a glossary, and charts and figures to promote learning. Discussion questions reinforce critical material.

The Handbook of Orthodontics offers a concise and accessible overview of the scientific and clinical basis of orthodontics.This popular textbook explores the concepts of occlusion and malocclusion, craniofacial development, postnatal growth and development of the dentition. It takes the reader through the principles of patient examination, orthodontic diagnosis and treatment planning - with detailed chapters on the management of malocclusion, dentofacial orthopaedics, fixed appliances, skeletal anchorage, aligner systems and orthognathic surgery. There is a strong emphasis on evidence-based medicine throughout, with a dedicated chapter outlining the theoretical basis of good clinical research and critical appraisal, with summaries of the latest clinical evidence throughout the book.A clear writing style and the inclusion of over 500 high-quality illustrations make the Handbook a defining text for postgraduate students training for specialist exams and dental undergraduates wanting to learn more about clinical orthodontics. - Covers the theoretical basis of orthodontics in detail, including definitive chapters on craniofacial development, postnatal growth, development of the dentition and craniofacial syndromes. - Full coverage of clinical orthodontics including examination, diagnosis and the use of contemporary removable, fixed and clear aligner appliance systems. - Evidence-based updates are present throughout – ideal for students wanting a comprehensive overview of the latest clinical research. - Controversies and areas of special interest are covered in standalone text boxes. - Consolidated bibliography with short summaries of important papers so you can easily keep up to date. - More than 500 illustrations and photographs to help explain and illustrate specific points. - Easy to read and navigate – helps you to understand the complex concepts. - Small enough to carry around with you as a quick reference guide. - New chapters on Dentofacial orthopaedics, Skeletal anchorage and Clear aligner systems. - Over 150 new figures